Robert Desborough
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View article: Cystatin C vs creatinine eGFR in advanced CKD: an analysis of the STOP-ACEi trial
Cystatin C vs creatinine eGFR in advanced CKD: an analysis of the STOP-ACEi trial Open
Background In this secondary analysis of the STOP-ACEi trial, we explored the impact of discontinuing or continuing renin–angiotensin system inhibitor therapy in people with advanced chronic kidney disease on cystatin C estimated glomerula…
View article: Cystatin C as a Marker of Kidney Function in Children
Cystatin C as a Marker of Kidney Function in Children Open
This review examines the reliability of cystatin C as a biomarker for kidney function in paediatric populations. Chronic kidney disease (CKD) affects a significant number of children globally, leading to severe health complications such as…
View article: WCN24-398 REPORT ON STOP-ACEi TRIAL: REVIEWING CYSTATIN C LEVELS IN CKD PATIENTS
WCN24-398 REPORT ON STOP-ACEi TRIAL: REVIEWING CYSTATIN C LEVELS IN CKD PATIENTS Open
In this pre-specified secondary analysis of the STOP-ACEi trial (1-2), we explored the impact of stopping or continuing renin angiotensin system (RAS) inhibitor therapy in people with advanced CKD on serum cystatin C levels.
View article: Unveiling the Untapped Potential: Cystatin C Testing in Kidney Function Assessment
Unveiling the Untapped Potential: Cystatin C Testing in Kidney Function Assessment Open
The burden of Chronic Kidney Disease (CKD) remains a growing public health problem. In 2019, the worldwide prevalence was estimated at 7.2 to 13.4%, with CKD incidence, prevalence, mortality and disability-adjusted life years having risen …
View article: Should Cystatin C eGFR Become Routine Clinical Practice?
Should Cystatin C eGFR Become Routine Clinical Practice? Open
Kidney function assessment is crucial for diagnosing and managing kidney diseases. Glomerular filtration rate (GFR) is widely used as an indicator of kidney function, but its direct measurement is challenging. Serum creatinine, a commonly …
View article: Clinical and biochemical characteristics of adults with hypophosphatasia attending a metabolic bone clinic
Clinical and biochemical characteristics of adults with hypophosphatasia attending a metabolic bone clinic Open
This study supported the use of ALP and PLP measurements as predictive of HPP diagnosis along with certain demographic and clinical characteristics (younger age, metatarsal or femoral fractures without low mean BMD T- and Z-scores on a DXA…