Robert H. Coker
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View article: Dietary proteins, amino acids and insulin resistance: a mini review
Dietary proteins, amino acids and insulin resistance: a mini review Open
The influence of protein intake on insulin resistance, has garnered an increasing amount of interest over the past few decades. Increased provisions of dietary protein during weight loss helps preserve skeletal muscle, which as the largest…
View article: Sex-specific energy expenditure during the Alaska mountain wilderness ski classic; insights from an Arctic winter expedition
Sex-specific energy expenditure during the Alaska mountain wilderness ski classic; insights from an Arctic winter expedition Open
Purpose The Alaska Mountain Wilderness Ski Classic (AMWSC) is a self-supported and self-oriented winter expedition that occurs in the remote North American Brooks Range, ∼200 km north of the Arctic Circle. Few investigations have evaluated…
View article: Acute changes in urinary metabolites: vinyasa yoga compared to cycle ergometer exercise
Acute changes in urinary metabolites: vinyasa yoga compared to cycle ergometer exercise Open
Introduction Increased interest in unconventional exercise such as vinyasa yoga has outpaced our understanding of the physiological response to yoga exercise. The objective of the current study was to evaluate changes in urinary metabolite…
View article: Preliminary comparisons between a point-of-care ketometer and reference method using Steller sea lion pup whole blood and plasma
Preliminary comparisons between a point-of-care ketometer and reference method using Steller sea lion pup whole blood and plasma Open
We evaluated the Precision Xtra™ ketometer as part of a larger study categorizing fasting status of free-ranging Steller sea lion (Eumetopias jubatus; SSL) pups which necessitated the identification of plasma β-hydroxybutyrate concentratio…
View article: Alaska Backcountry Expeditionary Hunting Promotes Sustained Muscle Protein Synthesis
Alaska Backcountry Expeditionary Hunting Promotes Sustained Muscle Protein Synthesis Open
Introduction We have previously described negative energy balance (ie, −9.7±3.4 MJ/d) and weight loss (Δ−1.5 ± 0.7 kg) influenced by high levels of energy expenditure (ie, 17.4±2.6 MJ/d) during remote expeditionary hunting in Alaska. Despi…
View article: Fasting durations of Steller sea lion pups vary among subpopulations—evidence from two plasma metabolites
Fasting durations of Steller sea lion pups vary among subpopulations—evidence from two plasma metabolites Open
Geographic differences in population growth trends are well-documented in Steller sea lions (Eumetopias jubatus), a species of North Pacific pinniped listed under the U.S. Endangered Species Act in 1990 following a marked decline in popula…
View article: Adiponectin, leptin, cortisol, neuropeptide Y and profile of mood states in athletes participating in an ultramarathon during winter: An observational study
Adiponectin, leptin, cortisol, neuropeptide Y and profile of mood states in athletes participating in an ultramarathon during winter: An observational study Open
Background: The Montane ® Yukon Arctic Ultra (YAU) is one of the longest (690 km) and coldest (+10.6°C–43.9°C) ultramarathons worldwide. Taking part in an ultramarathon is associated with great physiological and psychological stress, which…
View article: Essential amino acid enriched meal replacement improves body composition and physical function in obese older adults: A randomized controlled trial
Essential amino acid enriched meal replacement improves body composition and physical function in obese older adults: A randomized controlled trial Open
View article: Once/Day Provision of Essential Amino Acid Enriched Meal Replacement Improves Body Composition and Physical Function in Obese Elderly
Once/Day Provision of Essential Amino Acid Enriched Meal Replacement Improves Body Composition and Physical Function in Obese Elderly Open
We have previously demonstrated that the acute ingestion of essential amino acids may augment net protein balance in the elderly. Using a double blind, randomized controlled trial, our objective was to compare an experimental meal replacem…
View article: Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef
Equivalent servings of free-range reindeer promote greater net protein balance compared to commercial beef Open
Wild game consumption has been associated with health benefits but the acute influence on human protein metabolism remains unknown. We compared feeding-induced responses of equivalent amounts of free-range reindeer (FR) and commercial beef…
View article: Alaska backcountry expeditionary hunting promotes rapid improvements in metabolic biomarkers in healthy males and females
Alaska backcountry expeditionary hunting promotes rapid improvements in metabolic biomarkers in healthy males and females Open
We have previously reported negative energy balance and health benefits during an Alaska backcountry expeditionary hunting (ABEH) immersion in two males. The purpose of our present study was to increase the number of participants, include …
View article: Physical Activity Levels in Alaska Native Children Participating in the SkiKu/AK Nordic Program
Physical Activity Levels in Alaska Native Children Participating in the SkiKu/AK Nordic Program Open
Background: Physical activity is recommended to mitigate the incidence of obesity, but delivery of community wide initiatives is cumbersome. The challenges met by such programs are magnified when implementation transpires in the remote vil…
View article: Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels
Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels Open
View article: Higher Net Protein Balance Following the Ingestion of Free Range Reindeer Compared to Commercial Beef
Higher Net Protein Balance Following the Ingestion of Free Range Reindeer Compared to Commercial Beef Open
Wild game consumption has been associated with health benefits, but the influence on protein metabolism remains unknown. We compared the feeding-induced response to 2 oz of free-range reindeer (FR) versus commercial beef (CB) using stable …
View article: Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption
Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption Open
Excess alcohol consumption is a top risk factor for death and disability. Fatty liver will likely develop and the risk of liver disease increases. We have previously demonstrated that an essential amino acid supplement (EAAS) improved prot…
View article: Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption
Essential Amino Acid Supplement Lowers Intrahepatic Lipid despite Excess Alcohol Consumption Open
Excess alcohol consumption is a top risk factor for death and disability. Fatty liver will likely develop and the risk of liver disease increases. We have previously demonstrated that an essential amino acid supplement (EAAS) improved prot…
View article: Feasibility of connecting regional research programs to national multisite trials emanating from the CTSA Trial Innovation Network
Feasibility of connecting regional research programs to national multisite trials emanating from the CTSA Trial Innovation Network Open
A collaborative research model was developed and tested to enable regional healthcare systems to join multisite clinical trials emanating from the Clinical and Translational Science Award (CTSA) Trial Innovation Network (TIN) by the Instit…
View article: Wildland Firefighting
Wildland Firefighting Open
The observed maladaptive changes in adipose tissue, blood lipids, and hepatic function may reflect adaptations/consequences to occupational demands/conditions and warrant evaluation of appropriate countermeasures.
View article: Negative Energy Balance Does Not Alter Fat-Free Mass During the Yukon Arctic Ultra—The Longest and the Coldest Ultramarathon
Negative Energy Balance Does Not Alter Fat-Free Mass During the Yukon Arctic Ultra—The Longest and the Coldest Ultramarathon Open
Purpose: The objective of this study was to determine alterations in caloric balance, body composition, metabolites, and cytokines in athletes participating in the Yukon Arctic Ultra. Methods: Ten participants traveling on foot in the 2017…
View article: Essential amino acid-enriched meal replacement promotes superior net protein balance in older, overweight adults
Essential amino acid-enriched meal replacement promotes superior net protein balance in older, overweight adults Open
View article: The energy requirements and metabolic benefits of wilderness hunting in Alaska
The energy requirements and metabolic benefits of wilderness hunting in Alaska Open
The purported healthy aspects of subsistence foods have led to the popularity of the Paleo diet. There has been very little focus, surprisingly, on health benefits derived from the nomadic nature of humans during the Paleolithic era. The p…
View article: Cardiac Autonomic Modulations and Psychological Correlates in the Yukon Arctic Ultra: The Longest and the Coldest Ultramarathon
Cardiac Autonomic Modulations and Psychological Correlates in the Yukon Arctic Ultra: The Longest and the Coldest Ultramarathon Open
Studies on human physical performance in extreme environments have effectively approached the investigation of adaptation mechanisms and their physiological limits. As scientific interest in the interplay between physiological and psycholo…
View article: Weight Loss Strategies in the Elderly: A Clinical Conundrum
Weight Loss Strategies in the Elderly: A Clinical Conundrum Open
The age‐related concomitant loss of skeletal muscle and accumulation of excess adipose tissue have been commonly referred to as sarcopenic obesity. While weight loss may help mitigate the metabolic abnormalities linked to obesity, low fitn…
View article: Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial
Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial Open
View article: The Northwest Participant and Clinical Interactions Network: Increasing opportunities for patients to participate in research across the Northwestern United States
The Northwest Participant and Clinical Interactions Network: Increasing opportunities for patients to participate in research across the Northwestern United States Open
Introduction The Institute of Translational Health Sciences (ITHS) promotes and supports translational research collaboration between clinicians, communities, and investigators across the five-state Washington, Wyoming, Alaska, Montana, an…
View article: Feasibility of Conducting a 6-Months Long Home-based Exercise Program with Protein Supplementation in Elderly Community-dwelling Individuals with Heart Failure
Feasibility of Conducting a 6-Months Long Home-based Exercise Program with Protein Supplementation in Elderly Community-dwelling Individuals with Heart Failure Open
These findings suggest that with a larger cohort, this intervention may show significant positive effects for elderly patients who are at risk of developing cardiac cachexia.
View article: Metabolic Responses to the Yukon Arctic Ultra
Metabolic Responses to the Yukon Arctic Ultra Open
The influence of cold exposure and extreme physical exertion may promote substantial increases in serum irisin, and specific alterations in substrate metabolism that largely preserve skeletal muscle and physiological resilience.
View article: Nutritional Supplementation with Essential Amino Acids and Phytosterols May Reduce Risk for Metabolic Syndrome and Cardiovascular Disease in Overweight Individuals with Mild Hyperlipidemia.
Nutritional Supplementation with Essential Amino Acids and Phytosterols May Reduce Risk for Metabolic Syndrome and Cardiovascular Disease in Overweight Individuals with Mild Hyperlipidemia. Open
These findings suggest that a dietary supplementation of EAAs and phytosterols may promote favorable reductions of blood lipids as well as insulin resistance in individuals with hypertriglyceridemia. Future larger studies of SNPs and TG re…
View article: Exercise Training and Insulin Resistance: A Current Review
Exercise Training and Insulin Resistance: A Current Review Open
There is a general perception that increased physical activity will improve glucose homeostasis in all individuals. While this is an attractive concept, this conclusion may be overly simplistic and even misleading. The topic was reviewed e…