Robert H. Roth
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View article: Frailty and associated healthcare expenditures among patients undergoing total hip and knee arthroplasty
Frailty and associated healthcare expenditures among patients undergoing total hip and knee arthroplasty Open
View article: Central Sleep Apnea in Patients With Coronary Heart Disease Taking P2Y12 Inhibitors
Central Sleep Apnea in Patients With Coronary Heart Disease Taking P2Y12 Inhibitors Open
Central sleep apnea (CSA) is common in patients with heart failure. Recent studies link ticagrelor use with CSA. We aimed to evaluate CSA prevalence in patients with coronary heart disease (CHD) and whether ticagrelor use is associated wit…
View article: Delayed esophageal anastomotic complication and ramucirumab therapy: A case report
Delayed esophageal anastomotic complication and ramucirumab therapy: A case report Open
Current NCCN guidelines for second‐line therapy in recurrent or metastatic esophago‐gastric cancers recommend the use of VEGF inhibitors such as ramucirumab. VEGF inhibitors have been shown to be associated with gastrointestinal perforatio…
View article: 0720 Accuracy of WatchPat Portable Sleep Monitoring and Sleep Assessment in Patients with Atrial Fibrillation
0720 Accuracy of WatchPat Portable Sleep Monitoring and Sleep Assessment in Patients with Atrial Fibrillation Open
Introduction Obstructive sleep apnea(OSA) is an established risk factor for atrial fibrillation(AF), necessitating early diagnosis and management. Home-based sleep-monitoring technology has become a mainstream diagnostic modality. Peripher…
View article: 0723 Elucidation of Obstructive Sleep Apnea-Related Heart Rate Response Using a Novel Continuous Beat to Beat Blood Pressure Monitoring Technology
0723 Elucidation of Obstructive Sleep Apnea-Related Heart Rate Response Using a Novel Continuous Beat to Beat Blood Pressure Monitoring Technology Open
Introduction Obstructive sleep apnea (OSA) episode related sympathetic surge may mediate the association of OSA with cardiovascular disease. Heart rate (HR) response (HRR) to OSA events may reflect magnitude of sympathetic surge but is exp…
View article: Sleep time and efficiency in patients undergoing laboratory-based polysomnography
Sleep time and efficiency in patients undergoing laboratory-based polysomnography Open
View article: Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate Brain
Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate Brain Open
Vectors derived from adeno-associated virus (AAV) are promising candidates for neural cell transduction in vivo because they are nonpathogenic and achieve long-term transduction in the central nervous system. AAV serotype 2 (AAV2) is the m…
View article: Comparison of Fetal Mesencephalic Grafts, AAV-delivered GDNF, and Both Combined in an MPTP-induced Nonhuman Primate Parkinson’s Model
Comparison of Fetal Mesencephalic Grafts, AAV-delivered GDNF, and Both Combined in an MPTP-induced Nonhuman Primate Parkinson’s Model Open
We combined viral vector delivery of human glial-derived neurotrophic factor (GDNF) with the grafting of dopamine (DA) precursor cells from fetal ventral mesencephalon (VM) to determine whether these strategies would improve the anti-Parki…
View article: Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism
Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism Open
View article: Cognitive performance of juvenile monkeys after chronic fluoxetine treatment
Cognitive performance of juvenile monkeys after chronic fluoxetine treatment Open
Potential long term effects on brain development are a concern when drugs are used to treat depression and anxiety in childhood. In this study, male juvenile rhesus monkeys (three-four years of age) were dosed with fluoxetine or vehicle (N…
View article: Hydrothermal Dissolution of Opal in Sodium Hydroxide Lyes for the Synthesis of Water Glass
Hydrothermal Dissolution of Opal in Sodium Hydroxide Lyes for the Synthesis of Water Glass Open
Common opal was dissolved in NaOH lyes in rotating autoclaves. The starting material was characterized by X-ray diffraction and adsorption spectroscopy, thermal and chemical analysis, electron and atomic force microscopy. The opal proved t…
View article: A Potential Compensatory Role for Endogenous Striatal Tyrosine Hydroxylase-Positive Neurons in a Nonhuman Primate Model of Parkinson's Disease
A Potential Compensatory Role for Endogenous Striatal Tyrosine Hydroxylase-Positive Neurons in a Nonhuman Primate Model of Parkinson's Disease Open
The possibility of enhancing endogenous brain repair following neurological disorders, such as Parkinson's disease (PD), is of considerable recent interest. One such mechanism may exist in the striatum as an upregulated population of tyros…
View article: Influence of Temperature and Water Vapour Pressure on Drying Kinetics and Colloidal Microstructure of Dried Sodium Water Glass
Influence of Temperature and Water Vapour Pressure on Drying Kinetics and Colloidal Microstructure of Dried Sodium Water Glass Open
Industrially produced sodium water glasses were dried in climates with controlled temperature and humidity to transparent amorphous water containing sodium silicate materials. The water glasses had molar SiO2:Na2O ratios of 2.2, 3.3 and 3.…