Scott C. Weaver
YOU?
Author Swipe
View article: Mosquito host background impacts microbiome-Zika virus interactions in field- and laboratory-reared Aedes aegypti
Mosquito host background impacts microbiome-Zika virus interactions in field- and laboratory-reared Aedes aegypti Open
Mosquito microbiota abundance and composition are modulated by a variety of factors, including pathogen exposure. The microbiome can also influence pathogen infection of the host and thus harbours considerable potential to impact transmiss…
View article: A Multiplex Serological Assay for Quantification of Arbovirus Antibody Kinetics and Neutralizing Antibodies
A Multiplex Serological Assay for Quantification of Arbovirus Antibody Kinetics and Neutralizing Antibodies Open
Arboviruses such as dengue virus (DENV) and chikungunya virus (CHIKV) pose major global health threats. To support serological surveillance and study cross-reactivity, an in-house multiplex bead-based immunoassay was developed to measure I…
View article: Rhesus macaques model human Mayaro virus disease and transmit to Aedes aegypti mosquitoes
Rhesus macaques model human Mayaro virus disease and transmit to Aedes aegypti mosquitoes Open
Background Mayaro virus (MAYV) is a mosquito-borne alphavirus endemic to Latin America that causes fever and arthritis. Unlike the related chikungunya virus, MAYV has not caused widespread, human-amplified epidemics. One possible explanati…
View article: Entomological surveys and insecticide resistance in the dengue vector Aedes aegypti in Dakar, Senegal: First detection of the kdr mutation
Entomological surveys and insecticide resistance in the dengue vector Aedes aegypti in Dakar, Senegal: First detection of the kdr mutation Open
Aedes aegypti is the primary vector of arboviruses in Senegal, yet this species is not typically targeted by routine vector control programs. Through entomological surveillance, we investigated over a one-year (2022–2023) the risk of arbov…
View article: Arthropod-borne disease challenges from planetary warming, urbanization, and migration
Arthropod-borne disease challenges from planetary warming, urbanization, and migration Open
View article: Active West Nile virus transmission in Brazil: an epidemiological study
Active West Nile virus transmission in Brazil: an epidemiological study Open
View article: Genomic characterization of arboviruses discovered between the 1950s and 1980s
Genomic characterization of arboviruses discovered between the 1950s and 1980s Open
Arthropod-borne viruses (arboviruses) pose a major threat to global public health, impacting both human and animal health. Genomic characterization is important for arboviruses because it allows for an understanding of their evolution and …
View article: Eastern Equine Encephalitis Virus Exhibits More Charged Amino Acids in Its Envelope Proteins, Compared to Madariaga Virus
Eastern Equine Encephalitis Virus Exhibits More Charged Amino Acids in Its Envelope Proteins, Compared to Madariaga Virus Open
Given the importance of eastern equine encephalitis virus (EEEV; complex lineage I) in veterinary and public health in North America, there is limited knowledge about lineages II, III, and IV, also known as Madariaga virus (MADV), which ar…
View article: International Multi-site Implementation of Local Cell-Free Protein Biomanufacturing to Advance Health and Research Equity
International Multi-site Implementation of Local Cell-Free Protein Biomanufacturing to Advance Health and Research Equity Open
Limitations in global access to research and healthcare capacity undermine equity, sustainability, and resilience, particularly in resource-limited settings. Molecular diagnostics and biologic therapeutics are set to revolutionize medicine…
View article: Challenging the notion of Aedes aegypti as the primary chikungunya virus vector: insights from Kédougou, Southeastern Senegal
Challenging the notion of Aedes aegypti as the primary chikungunya virus vector: insights from Kédougou, Southeastern Senegal Open
Background Chikungunya fever (CHIK) caused by the mosquito-borne chikungunya virus (CHIKV) and transmitted by Aedes mosquitoes, remains a public health burden throughout the tropics. During the CHIK outbreak in the southeastern Senegal in …
View article: Proceedings from the Fourth Mesoamerican Symposium “Dr. Roberto Navarro López” on Emerging Zoonotic Disease and Arboviruses: Commenting Insights and Research Findings
Proceedings from the Fourth Mesoamerican Symposium “Dr. Roberto Navarro López” on Emerging Zoonotic Disease and Arboviruses: Commenting Insights and Research Findings Open
Zoonotic pathogens such as arboviruses, arenaviruses, filoviruses, coronaviruses, highly pathogenic Avian Influenza A (H5N1) viruses, vesiculoviruses, and many others are emerging and reemerging worldwide, jeopardizing global veterinary an…
View article: Survey of Fleas and Ticks for Rickettsia rickettsii and Rickettsia typhi in the El Paso Community and Other Areas in Texas, New Mexico, and Ciudad Juarez, Mexico
Survey of Fleas and Ticks for Rickettsia rickettsii and Rickettsia typhi in the El Paso Community and Other Areas in Texas, New Mexico, and Ciudad Juarez, Mexico Open
This survey was conducted with the aim of determining the public health risk of Rocky Mountain spotted fever and murine typhus in the urban and peri-urban areas of El Paso, as well as other areas in Texas, southern New Mexico, and Ciudad J…
View article: Correction: Long-term persistence of serum IgM antibodies against chikungunya virus in patients with chronic arthralgia
Correction: Long-term persistence of serum IgM antibodies against chikungunya virus in patients with chronic arthralgia Open
View article: Chikungunya virus and other emerging arthritogenic alphaviruses
Chikungunya virus and other emerging arthritogenic alphaviruses Open
View article: Mosquito-Based Detection of Endogenous Jaagsiekte Sheep Retrovirus in Senegal: Expanding the Scope of Xenosurveillance
Mosquito-Based Detection of Endogenous Jaagsiekte Sheep Retrovirus in Senegal: Expanding the Scope of Xenosurveillance Open
View article: Rhesus macaques model human Mayaro virus disease and transmit to <i>Aedes aegypti</i> mosquitoes
Rhesus macaques model human Mayaro virus disease and transmit to <i>Aedes aegypti</i> mosquitoes Open
Background Mayaro virus (MAYV) is a mosquito-borne alphavirus endemic to Latin America that causes fever and arthritis. Unlike the related chikungunya virus, MAYV has not caused widespread, human-amplified epidemics. One possible explanati…
View article: Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs
Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs Open
Mosquito-borne viruses pose a significant, global threat to human and animal health. Traditionally, arthropod-borne virus (arbovirus) surveillance has been retroactive following an outbreak, which limits the ability to predict and prevent …
View article: Optimization of a panel of behavioral tests for use in containment using a golden Syrian hamster model
Optimization of a panel of behavioral tests for use in containment using a golden Syrian hamster model Open
View article: Cross-neutralizing activity of the chikungunya vaccine VLA1553 against three prevalent chikungunya lineages
Cross-neutralizing activity of the chikungunya vaccine VLA1553 against three prevalent chikungunya lineages Open
Cross-neutralization is generally a prerequisite for cross-protection of vaccines against diseases caused by heterologous viruses. Using sera obtained from a randomized clinical phase 3 trial in adults, we investigated the cross-neutraliza…
View article: Mosquito host background influences microbiome-ZIKV interactions in field and laboratory-reared <i>Aedes aegypti</i>
Mosquito host background influences microbiome-ZIKV interactions in field and laboratory-reared <i>Aedes aegypti</i> Open
The mosquito microbiota represents an intricate assemblage of microorganisms, comprising bacteria, fungi, viruses, and protozoa. Factors modulating microbiome abundance and composition include host genetic background, environmental paramet…
View article: High-resolution spatiotemporal analysis of chikungunya epidemics between 2019 and 2020 in Salvador, Brazil: a municipality-level transmission dynamics study
High-resolution spatiotemporal analysis of chikungunya epidemics between 2019 and 2020 in Salvador, Brazil: a municipality-level transmission dynamics study Open
Secretary of Health of Salvador, Federal University of Bahia, Oswaldo Cruz Foundation, National Council for Scientific and Technological Development, Foundation for Research Support of the Bahia State, Coordenação de Aperfeiçoamento de Pes…
View article: Molecular basis for shifted receptor recognition by an encephalitic arbovirus
Molecular basis for shifted receptor recognition by an encephalitic arbovirus Open
After decades of inactivity throughout the Americas, western equine encephalitis virus (WEEV) recently re-emerged in South America, causing a large-scale outbreak in humans and horses. WEEV binds protocadherin 10 (PCDH10) as a receptor; ho…
View article: Cache Valley virus isolation from a horse in Veracruz State, Mexico
Cache Valley virus isolation from a horse in Veracruz State, Mexico Open
Cache Valley virus (CVV) was isolated from a clinically presenting horse in the Mexican Gulf region. CVV is linked to neuroinvasive disease in humans and fetal demise and defects in sheep. This is the first association between CVV and dise…
View article: Potential role of heterologous flavivirus immunity in preventing urban transmission of yellow fever virus
Potential role of heterologous flavivirus immunity in preventing urban transmission of yellow fever virus Open
View article: Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection
Three positively charged binding sites on the eastern equine encephalitis virus E2 glycoprotein coordinate heparan sulfate- and protein receptor-dependent infection Open
SUMMARY Naturally circulating strains of eastern equine encephalitis virus (EEEV) bind heparan sulfate (HS) receptors and this interaction has been linked to its neurovirulence. Previous studies associated EEEV-HS interactions with three p…
View article: Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study
Re-emergence of Oropouche virus between 2023 and 2024 in Brazil: an observational epidemiological study Open
For the Portuguese translation of the abstract see Supplementary Materials section.
View article: Outbreak of Chikungunya Fever in the Central Valley of Chiapas, Mexico
Outbreak of Chikungunya Fever in the Central Valley of Chiapas, Mexico Open
Chikungunya virus (CHIKV) was isolated from humans in an outbreak of a febrile illness during July and August 2015 in the central valleys of Chiapas, Mexico. Sera obtained from 80 patients were tested for CHIKV RNA by reverse transcriptase…
View article: Molecular Epidemiology of Western Equine Encephalitis Virus, South America, 2023–2024
Molecular Epidemiology of Western Equine Encephalitis Virus, South America, 2023–2024 Open
Western equine encephalitis virus (WEEV) is a mosquitoborne virus that reemerged in December 2023 in Argentina and Uruguay, causing a major outbreak. We investigated the outbreak using epidemiologic, entomological, and genomic analyses, fo…
View article: Reemergence of Oropouche virus between 2023 and 2024 in Brazil
Reemergence of Oropouche virus between 2023 and 2024 in Brazil Open
Background Oropouche virus (OROV; species Orthobunyavirus oropoucheense ) is an arthropod-borne virus that has caused outbreaks of Oropouche fever in Central and South America since the 1950s. This study investigates virological factors co…
View article: Using one health training for interprofessional team building: implications for research, policy, and practice in Nigeria
Using one health training for interprofessional team building: implications for research, policy, and practice in Nigeria Open
In recent years, the concept of One Health (OH) has arisen as an approach that helps to catalyze the creation of transdisciplinary teams needed for surveillance and investigation of emerging disease dynamics. Besides a wealth of descriptio…