Robert K. Yu
YOU?
Author Swipe
View article: Coptisine alleviates MNNG-induced GES-1 cell damage and chronic atrophic gastritis in rats by modulating apoptosis-related proteins, amino acid metabolism, and the PI3K/Akt signaling pathway
Coptisine alleviates MNNG-induced GES-1 cell damage and chronic atrophic gastritis in rats by modulating apoptosis-related proteins, amino acid metabolism, and the PI3K/Akt signaling pathway Open
View article: The mediating role of resilience in the relationship between empowerment and benefit finding among Chinese colorectal cancer patients
The mediating role of resilience in the relationship between empowerment and benefit finding among Chinese colorectal cancer patients Open
View article: Regional hyperconnectivity in the medial temporal lobes as a maladaptive mechanism for colorectal cancer-related cognitive decline
Regional hyperconnectivity in the medial temporal lobes as a maladaptive mechanism for colorectal cancer-related cognitive decline Open
View article: Pantothenic acid plays an important role in reducing body weight
Pantothenic acid plays an important role in reducing body weight Open
Background: Obesity is characterized by excessive fat accumulation. Strategies to effectively curb the prevalence of obesity have always garnered significant attention. If reducing fat can be achieved by altering the content of certain nut…
View article: Targeting Mutant Protein Kinase B with Lysine-Selective Salicylaldehyde Inhibitors and Zn2⁺ Chelation: A Novel Therapeutic Strategy
Targeting Mutant Protein Kinase B with Lysine-Selective Salicylaldehyde Inhibitors and Zn2⁺ Chelation: A Novel Therapeutic Strategy Open
View article: Vid-SME: Membership Inference Attacks against Large Video Understanding Models
Vid-SME: Membership Inference Attacks against Large Video Understanding Models Open
Multimodal large language models (MLLMs) demonstrate remarkable capabilities in handling complex multimodal tasks and are increasingly adopted in video understanding applications. However, their rapid advancement raises serious data privac…
View article: The structure of human sweetness
The structure of human sweetness Open
In humans, the detection and ultimately the perception of sweetness begin in the oral cavity, where taste receptor cells (TRCs) dedicated to sweet-sensing interact with sugars, artificial sweeteners, and other sweet-tasting chemicals. Huma…
View article: Digital and artificial intelligence-assisted cephalometric training effectively enhanced students’ landmarking accuracy in preclinical orthodontic education
Digital and artificial intelligence-assisted cephalometric training effectively enhanced students’ landmarking accuracy in preclinical orthodontic education Open
Digital cephalometric training effectively enhances students' landmarking accuracy in preclinical orthodontic education. AI-assisted cephalometry has the potential to minimize performance disparities among students with varying levels of c…
View article: Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP‐mediated transrepression pathway
Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP‐mediated transrepression pathway Open
The accumulation of lactate in tissue microenvironments is associated with atherosclerosis, but its precise role in atherogenesis remains largely unknown. This study demonstrated that lactate accumulation in aortic tissues and blood is cor…
View article: Development and Evaluation of a P. Multocida A-M. Haemolytica A6-Rlkt Combined Vaccine for Enhanced Control of Bovine Respiratory Disease Complex
Development and Evaluation of a P. Multocida A-M. Haemolytica A6-Rlkt Combined Vaccine for Enhanced Control of Bovine Respiratory Disease Complex Open
View article: Pantothenic Acid Plays an Important Role in Weight Loss
Pantothenic Acid Plays an Important Role in Weight Loss Open
View article: Research on the English Translation of Urumqi Municipal Museum’s Introduction in the Perspective of Ecological Rationality
Research on the English Translation of Urumqi Municipal Museum’s Introduction in the Perspective of Ecological Rationality Open
The Urumqi Municipal Museum boasts a rich collection of resources, including 16 first-class cultural relics, 29 second-class relics, and 102 third-class relics, embodying the historical and cultural memories of Urumqi and narrating its cap…
View article: Microstructural Alterations of White Matter Associated With Colorectal Cancer-Related Cognitive Impairment
Microstructural Alterations of White Matter Associated With Colorectal Cancer-Related Cognitive Impairment Open
PURPOSE Colorectal cancer survivors exhibit impairments in information processing and working memory with no significantly added effects from adjuvant therapy (PMID: 26527785). Little is known regarding its neural mechanism, which greatly …
View article: Scalable Bayesian optimization with randomized prior networks
Scalable Bayesian optimization with randomized prior networks Open
View article: Ganglioside <scp>GD3</scp> regulates neural stem cell quiescence and controls postnatal neurogenesis
Ganglioside <span>GD3</span> regulates neural stem cell quiescence and controls postnatal neurogenesis Open
The postnatal neural stem cell (NSC) pool hosts quiescent and activated radial glia‐like NSCs contributing to neurogenesis throughout adulthood. However, the underlying regulatory mechanism during the transition from quiescent NSCs to acti…
View article: Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
Supplementary Tables 5-8. Supplementary Table 5. Unconditional and conditional analyses of 4 low LD SNPs after clump analysis using overall SCCHN data, conditioning on any three other SNPs in the table. Supplementary Table 6. Unconditional…
View article: Supplementary Table 1 from Cigarette Experimentation in Mexican Origin Youth: Psychosocial and Genetic Determinants
Supplementary Table 1 from Cigarette Experimentation in Mexican Origin Youth: Psychosocial and Genetic Determinants Open
XLS - 104K
View article: Supplementary Methods from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Methods from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 133K, Additional methods describing the segregation-linkage analysis approach with variable age at onset.
View article: Data from Cigarette Experimentation in Mexican Origin Youth: Psychosocial and Genetic Determinants
Data from Cigarette Experimentation in Mexican Origin Youth: Psychosocial and Genetic Determinants Open
Background: Established psychosocial risk factors increase the risk for experimentation among Mexican origin youth. Now, we comprehensively investigate the added contribution of select polymorphisms in candidate genetic pathways ass…
View article: Supplementary Figure 2 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Figure 2 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 102K, Linkage locations suggested by Loki on chromosome 17 by batches of 100K iterations and over all 500K iterations.
View article: Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
Supplementary Tables 5-8. Supplementary Table 5. Unconditional and conditional analyses of 4 low LD SNPs after clump analysis using overall SCCHN data, conditioning on any three other SNPs in the table. Supplementary Table 6. Unconditional…
View article: Data from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Data from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
Background: We propose a 2-step model-based approach, with correction for ascertainment, to linkage analysis of a binary trait with variable age of onset and apply it to a set of multiplex pedigrees segregating for adult glioma.M…
View article: Supplementary Figure 4 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Figure 4 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 89K, L-scores for three prior settings, after discarding the beginning 5K iterations
View article: Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
To identify genetic variants for risk of squamous cell carcinoma of the head and neck (SCCHN), we conducted a two-phase genome-wide association study consisting of 7,858,089 SNPs in 2,171 cases and 4,493 controls of non-Hispanic white, of …
View article: Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
To identify genetic variants for risk of squamous cell carcinoma of the head and neck (SCCHN), we conducted a two-phase genome-wide association study consisting of 7,858,089 SNPs in 2,171 cases and 4,493 controls of non-Hispanic white, of …
View article: Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
Supp Figures 1-7. Supplementary Figure 1: Workflow of the two-phase study (discovery and replication). Supplementary Figure 2: Proportion of ancestry inference using first and second principal component (PC) score in the discovery study (i…
View article: Supplementary Figure 3 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Figure 3 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 302K, Scatter plot of the visits at possible linked QTL locations on chromosome 17 vs. iteration.
View article: Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck Open
Supp Figures 1-7. Supplementary Figure 1: Workflow of the two-phase study (discovery and replication). Supplementary Figure 2: Proportion of ancestry inference using first and second principal component (PC) score in the discovery study (i…
View article: Supplementary Table 1 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Table 1 from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 34K, Typical assumptions in model-based vs. model-free multipoint linkage analysis.
View article: Supplementary Methods from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma
Supplementary Methods from A Variable Age of Onset Segregation Model for Linkage Analysis, with Correction for Ascertainment, Applied to Glioma Open
PDF file, 133K, Additional methods describing the segregation-linkage analysis approach with variable age at onset.