Robert Konkel
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View article: Combating Toxic Blooms of Prymnesium parvum: Hydrogen Peroxide Influence on the Haptophyte, Other Phytoplankton Taxa, and Concentrations of Prymnesins Under Experimental Conditions
Combating Toxic Blooms of Prymnesium parvum: Hydrogen Peroxide Influence on the Haptophyte, Other Phytoplankton Taxa, and Concentrations of Prymnesins Under Experimental Conditions Open
In the summer of 2022, massive blooms of the toxic haptophyte Prymnesium parvum triggered one of the most significant ecological disasters ever recorded in the Odra River, resulting in massive fish and mollusk kills and severe economic dam…
View article: Cytotoxic Activity of the Baltic Cyanobacterium Pseudanabaena galeata CCNP1313
Cytotoxic Activity of the Baltic Cyanobacterium Pseudanabaena galeata CCNP1313 Open
While tropical regions have traditionally been the focus of studies on natural bioactive products, works published within the last decade demonstrate that cyanobacteria from the Baltic Sea also possess significant biotechnological and phar…
View article: Unlocking the biotechnological potential of Baltic microorganisms
Unlocking the biotechnological potential of Baltic microorganisms Open
Marine microorganisms are increasingly recognized as valuable sources of bioactive compounds and enzymes with diverse applications in biotechnology. Despite its relatively low overall biodiversity, the Baltic Sea harbours a variety of diat…
View article: Aeruginosin 525 (AER525) from Cyanobacterium Aphanizomenon Sp. (KUCC C2): A New Serine Proteases Inhibitor
Aeruginosin 525 (AER525) from Cyanobacterium Aphanizomenon Sp. (KUCC C2): A New Serine Proteases Inhibitor Open
Aeruginosins (AERs) are one of the most common classes of cyanobacterial peptides synthesised through a hybrid non-ribosomal peptide synthase/polyketide synthase pathway. They have been found in Microcystis, Nodularia spumigena, Oscillator…
View article: S75 | CyanoMetDB | Comprehensive database of secondary metabolites from cyanobacteria
S75 | CyanoMetDB | Comprehensive database of secondary metabolites from cyanobacteria Open
CyanoMetDB is a comprehensive database of secondary metabolites from cyanobacteria manually curated from primary references described in Jones et al (2021), DOI: 10.1016/j.watres.2021.117017. Latest update: Sept. 2024 (V03). Dataset DOI: 1…
View article: Structural Diversity and Biological Activity of Cyanopeptolins Produced by Nostoc edaphicum CCNP1411
Structural Diversity and Biological Activity of Cyanopeptolins Produced by Nostoc edaphicum CCNP1411 Open
Cyanopeptolins (CPs) are one of the most commonly occurring class of cyanobacterial nonribosomal peptides. For the majority of these compounds, protease inhibition has been reported. In the current work, the structural diversity of cyanope…
View article: S75 | CyanoMetDB | Comprehensive database of secondary metabolites from cyanobacteria
S75 | CyanoMetDB | Comprehensive database of secondary metabolites from cyanobacteria Open
This is the collection associated with list S75 CyanoMetDB Comprehensive database of secondary metabolites from cyanobacteria on the NORMAN Suspect List Exchange. https://www.norman-network.com/nds/SLE/ CyanoMetDB is a comprehensive databa…
View article: Anabaenopeptins from Nostoc edaphicum CCNP1411
Anabaenopeptins from Nostoc edaphicum CCNP1411 Open
Cyanobacteria of the Nostoc genus belong to the most prolific sources of bioactive metabolites. In our previous study on Nostoc edaphicum strain CCNP1411, the occurrence of cyanopeptolins and nostocyclopeptides was documented. In the curre…
View article: Antiviral Cyanometabolites—A Review
Antiviral Cyanometabolites—A Review Open
Global processes, such as climate change, frequent and distant travelling and population growth, increase the risk of viral infection spread. Unfortunately, the number of effective and accessible medicines for the prevention and treatment …
View article: Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea
Luciferase reporter assay for small-molecule inhibitors of MIR92b-3p function: Screening cyanopeptolins produced by Nostoc from the Baltic Sea Open
We developed a cell sensor that detects the liver cancer-specific microRNA MIR92b-3p, involved in hepatocellular carcinoma development and hepatitis C virus infection. To validate our small-molecule screen that employs a Huh7 human hepatom…
View article: Blooms of Toxic Cyanobacterium Nodularia spumigena in Norwegian Fjords During Holocene Warm Periods
Blooms of Toxic Cyanobacterium Nodularia spumigena in Norwegian Fjords During Holocene Warm Periods Open
In paleoecological studies, molecular markers are being used increasingly often to reconstruct community structures, environmental conditions and ecosystem changes. In this work, nodularin, anabaenopeptins and selected DNA sequences were a…
View article: Bioactive Peptides Produced by Cyanobacteria of the Genus Nostoc: A Review
Bioactive Peptides Produced by Cyanobacteria of the Genus Nostoc: A Review Open
Cyanobacteria of the genus Nostoc are widespread in all kinds of habitats. They occur in a free-living state or in association with other organisms. Members of this genus belong to prolific producers of bioactive metabolites, some of which…