Explanipedia

Polymeric micelle mediated follicular delivery of spironolactone: Targeting the mineralocorticoid receptor to prevent glucocorticoid-induced activation and delayed cutaneous wound healing Open

Naoual Dahmana, Thibault Mugnier, Doris Gabriel, Tatiana Favez, Laura Kowalczuk , et al. · 2021

Impaired wound healing in patients receiving glucocorticoid therapy is a serious clinical concern: mineralocorticoid receptor (MR) antagonists can counter glucocorticoid-induced off-target activation of MR receptors. The aim of this study …

Fatigue criteria for short fiber-reinforced thermoplastic validated over various fiber orientations, load ratios and environmental conditions Open

Prashanth Santharam, Yann Marco, V. Le Saux, Matthieu Le Saux, Robert Gurny , et al. · 2020

A mixed strain rate and energy based fatigue criterion for short fiber reinforced thermoplastics Open

Ilan Raphael, Nicolas Saintier, H. Rolland, Robert Gurny, Lucien Laiarinandrasana · 2019

On the role of the spherulitic microstructure in fatigue damage of pure polymer and glass-fiber reinforced semi-crystalline polyamide 6.6 Open

Ilan Raphael, Nicolas Saintier, Robert Gurny, J. Béga, Lucien Laiarinandrasana · 2019

Thermo-mechanical coupling of a viscoelastic-viscoplastic model for thermoplastic polymers: Thermodynamical derivation and experimental assessment Open

Anouar Krairi, Issam Doghri, Joanna Schalnat, Robert Gurny, Wim Van Paepegem · 2018

Fatigue damage mechanisms of short fiber reinforced PA66 as observed by in-situ synchrotron X-ray microtomography Open

H. Rolland, Nicolas Saintier, Ilan Raphael, Nicolas Lenoir, Andrew King , et al. · 2018

Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts Open

Frédéric Lallemand, Mathieu Schmitt, Jean‐Louis Bourges, Robert Gurny, Simon Benita , et al. · 2017

Local ocular delivery of cyclosporine A (CsA) is the preferred method for CsA delivery as a treatment for ocular inflammatory diseases such as uveitis, corneal healing, vernal keratoconjunctivitis and dry eye disease. However, due to the l…

Scaffolds for alternative delivery Open

Ilaria Bonetti, Olivier Kitten, Mathieu Cinier, Nadege Prel, Nghiep Truong Tan , et al. · 2016

In situ X-ray tomography investigation on damage mechanisms in short glass fibre reinforced thermoplastics: Effects of fibre orientation and relative humidity Open

H. Rolland, Nicolas Saintier, P. Wilson, Jonathan Merzeau, Robert Gurny · 2016

Therapeutic effect of topical treatment with everolimus-loaded nanocarriers in murine experimental autoimmune uveoretinitis (EAU). Open

Maren Kasper, Dirk Bauer, Lena Wildschuetz, Doris Gabriel, Herve Courthion , et al. · 2016

Histologic Assessment of Drug-Eluting Grafts Related to Implantation Site Open

Jean‐Christophe Tille, Sarra de Valence, Delia Mandracchia, Benjamin Nottelet, Francesco Innocente , et al. · 2016

Drug-eluting vascular prostheses represent a new direction in vascular surgery to reduce early thrombosis and late intimal hyperplasia for small calibre grafts. Subcutaneous implantation in rats is a rapid and cost-effective screening mode…

Damage mechanisms in short glass fibre reinforced thermoplastic during in situ microtomography tensile tests Open

H. Rolland, Nicolas Saintier, Robert Gurny · 2016

Fatigue mechanisms description in short glass fibre reinforced thermoplastic by microtomographic observations Open

H. Rolland, Nicolas Saintier, Nicolas Lenoir, Andrew King, Robert Gurny · 2016

Short glass fibre reinforced thermoplastics are promising materials for weight reduction of structures thanks to its very good specific mechanical properties. The current challenge is to provide experimental data concerning damage mechanis…

Micromechanical Fatigue Visco‐Damage Model for Short Glass Fiber Reinforced Polyamide‐66 Open

Nicolas Despringre, Yves Chemisky, Robert Gurny, Fodil Meraghni · 2015

This work presents a micromechanical fatigue damage model developed for short glass fiber reinforced PA66. It has been developed to predict the high cycle fatigue behavior of PA66/GF30. The model is based on an extended Mori-Tanaka method …

Moisture sorption in polyamide 6.6: Experimental investigation and comparison to four physical-based models Open

Morgane Broudin, V. Le Saux, Pierre‐Yves Le Gac, Clément Champy, Robert Gurny , et al. · 2015

Self-assembled polymeric nanocarriers for the targeted delivery of retinoic acid to the hair follicle Open

Maria Lapteva, Michael Möller, Robert Gurny, Yogeshvar N. Kalia · 2015

Acne vulgaris is a highly prevalent dermatological disease of the pilosebaceous unit (PSU). An inability to target drug delivery to the PSU results in poor treatment efficacy and the incidence of local side-effects. Cutaneous application o…

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