Reginald M. Penner
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View article: Selectivity in Chemiresistive Gas Sensors: Strategies and Challenges
Selectivity in Chemiresistive Gas Sensors: Strategies and Challenges Open
The demand for highly functional chemical gas sensors has surged due to the increasing awareness of human health to monitor metabolic disorders or noncommunicable diseases, safety measures against harmful greenhouse and/or explosive gases,…
View article: Inflammatory Bowel Disease Uncovered in Fecal Immunochemical Test Positive Patients in a Canadian Provincial Colon Cancer Screening Program
Inflammatory Bowel Disease Uncovered in Fecal Immunochemical Test Positive Patients in a Canadian Provincial Colon Cancer Screening Program Open
Objectives: Inflammatory Bowel Disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory condition that usually affects younger adults but has a second incidence peak in the older population. Mos…
P107 Comparing the Colonic Tissue Proteome of Active and Inactive Ulcerative Colitis Open
Background Ulcerative colitis (UC) is an inflammatory bowel disease that begins at the rectum and can advance proximally and continuously throughout the colon. In this pilot study, we aim to differentiate the protein expression between act…
Enhanced cycle lifetime with gel electrolyte for MnO<sub>2</sub> nanowire capacitors Open
A nanowire energy storage device such as a nanowire battery or a capacitor having a cathode comprising a plurality of nanowires and an anode comprising a plurality of nanowires interlaced with the plurality of nanowires of the cathode, and…
View article: Electrodeposition-enabled, electrically-transduced sensors and biosensors
Electrodeposition-enabled, electrically-transduced sensors and biosensors Open
Electrodeposition and electropolymerization have emerged as versatile tools for the fabrication of chemical and biosensors. The literature in this area, published since 2017, is the main focus of this review. Electropolymerization has play…
Enhancing the Sensitivity of the Virus BioResistor by Overoxidation: Detecting IgG Antibodies Open
The Virus BioResistor (VBR) is a biosensor capable of rapid and sensitive detection of small protein disease markers using a simple dip-and-read modality. For example, the bladder cancer-associated protein DJ-1 (22 kDa) can be detected in …
A60 SIGNIFICANCE OF IBD DIAGNOSIS IN THE BC COLON SCREENING PROGRAM Open
Background There has been evidence of incidental inflammatory bowel disease (IBD) diagnosis in otherwise asymptomatic patients during colonoscopy to follow-up a positive fecal immunochemical test (FIT). Little is known about the significan…
Viruses Masquerading as Antibodies in Biosensors: The Development of the Virus BioResistor Open
The 2018 Nobel Prize in Chemistry recognized in vitro evolution, including the development by George Smith and Gregory Winter of phage display, a technology for engineering the functional capabilities of antibodies into viruses. Such bacte…
View article: Moving Electrons Purposefully through Single Molecules and Nanostructures: A Tribute to the Science of Professor Nongjian Tao (1963–2020)
Moving Electrons Purposefully through Single Molecules and Nanostructures: A Tribute to the Science of Professor Nongjian Tao (1963–2020) Open
Electrochemistry intersected nanoscience 25 years ago when it became possible to control the flow of electrons through single molecules and nanostructures. Many surprises and a wealth of understanding were generated by these experiments. P…
Correction to Virus Bioresistor (VBR) for the Detection of the Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute Open
The author list contained an error: Gregory A. Weiss was not identified as a corresponding author. Both of the corresponding authors, Gregory A. Weiss and Reginald M. Penner, are indicated in this Addition and Correction.
Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute Open
DJ-1, a 20.7 kDa protein, is overexpressed in people who have bladder cancer (BC). Its elevated concentration in urine allows it to serve as a marker for BC. However, no biosensor for the detection of DJ-1 has been demonstrated. Here, we d…
View article: Electrode Degradation in Lithium-Ion Batteries
Electrode Degradation in Lithium-Ion Batteries Open
Although Li-ion batteries have emerged as the battery of choice for electric vehicles and large-scale smart grids, significant research efforts are devoted to identifying materials that offer higher energy density, longer cycle life, lower…
The 15th Anniversary of the U.S. National Nanotechnology Initiative Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTThe 15th Anniversary of the U.S. National Nanotechnology InitiativeWarren C. W. ChanWarren C. W. ChanMore by Warren C. W. Chanhttp://orcid.org/0000-0001-5435-4785, Manish ChhowallaManish ChhowallaM…
The Virus Bioresistor: Wiring Virus Particles for the Direct, Label-Free Detection of Target Proteins Open
The virus bioresistor (VBR) is a chemiresistor that directly transfers information from virus particles to an electrical circuit. Specifically, the VBR enables the label-free detection of a target protein that is recognized and bound by fi…
Supercharging a MnO<sub>2</sub> Nanowire: An Amine-Altered Morphology Retains Capacity at High Rates and Mass Loadings Open
The influence of hexamethylenetetraamine (HMTA) on the morphology of δ-MnO2 and its properties for electrical energy storage are investigated-specifically for ultrathick δ-MnO2 layers in the micron scale. Planar arrays of gold@δ-MnO2, core…
Collateral Advantages of a Gel Electrolyte for MnO<sub>2</sub> Nanowire Capacitors: Higher Voltage and Reduced Volume Open
Recently we demonstrated that symmetric, all Au@δ-MnO2 core@shell nanowire capacitors can achieve cycle stability to 100 000 cycles and beyond in a poly(methyl methacrylate) (PMMA) gel electrolyte. Here we examine the limits of the PMMA ge…
View article: Diverse Applications of Nanomedicine
Diverse Applications of Nanomedicine Open
The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine de…
Solid-State Ionic Diodes Demonstrated in Conical Nanopores Open
Ionic transport at the nanoscale features phenomena that are not observed in larger systems. Nonlinear current–voltage curves characteristic of ionic diodes as well as ion selectivity are examples of effects observed at the nanoscale. Many…
Ion transport in gel and gel–liquid systems for LiClO<sub>4</sub>-doped PMMA at the meso- and nanoscales Open
Ionic transport in gel electrolytes at the nano- and mesoscales is explored experimentally using single pores.
View article: Nanoscience and Nanotechnology Impacting Diverse Fields of Science, Engineering, and Medicine
Nanoscience and Nanotechnology Impacting Diverse Fields of Science, Engineering, and Medicine Open
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTNanoscience and Nanotechnology Impacting Diverse Fields of Science, Engineering, and MedicineWarren W. C. Chan, Manish Chhowalla, Sharon Glotzer, Yury Gogotsi, Jason H. Hafner, Paula T. Hammond, Ma…
Nano Day: Celebrating the Next Decade of Nanoscience and Nanotechnology Open
Nanoscience and nanotechnology are poised to contribute to a wide range of fields, from health and medicine to electronics, energy, security, and more. These contributions come both directly in the form of new materials, interfaces, tools,…
Impedance-Based Biosensing Using Virus-Poly(3,4-ethylenedioxythiophene) Open
Urinary bladder cancer is a worldwide issue that calls for critical attention of effective biosensors for early cancer detection. The advent of virus-biosensor technology presents a promising and non-invasive solution by quantitatively det…