R. Porter
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View article: Accidental pediatric death: a ten year retrospective cohort
Accidental pediatric death: a ten year retrospective cohort Open
Accident incidence differed significantly between NL provincial regions with rural areas manifesting more accidents per capita than urban areas. NL data was similar to MB and lower than NB in overall accidental death, cause specific death …
View article: Characterising tropical oyster reefs: invertebrate-environment associations and a newly documented reef building species
Characterising tropical oyster reefs: invertebrate-environment associations and a newly documented reef building species Open
Oyster reefs were once widespread across the global tropics but have often been excluded from global assessments of historical distributions, declines and conservation needs. Consequently, little is known about tropical oyster reefs, inclu…
View article: Multi-site desmoplastic small round cell tumors are genetically related and immune-cold
Multi-site desmoplastic small round cell tumors are genetically related and immune-cold Open
Desmoplastic small round cell tumor (DSRCT) is a highly aggressive soft tissue sarcoma that is characterized by the EWSR1-WT1 fusion protein. Patients present with hundreds of tumor implants in their abdominal cavity at various sites. To d…
View article: Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients
Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients Open
Osteosarcoma (OS) is a genetically diverse bone cancer that lacks a consistent targetable mutation. Recent studies suggest the IGF/PI3K/mTOR pathway and YAP/TAZ paralogs regulate cell fate and proliferation in response to biomechanical cue…
View article: Dissociation Protocols used for Sarcoma Tissues Bias the Transcriptome observed in Single-cell and Single-nucleus RNA sequencing
Dissociation Protocols used for Sarcoma Tissues Bias the Transcriptome observed in Single-cell and Single-nucleus RNA sequencing Open
Background Single-cell RNA-seq has emerged as an innovative technology used to study complex tissues and characterize cell types, states, and lineages at a single-cell level. Classification of bulk tumors by their individual cellular const…
View article: The Androgen Receptor: A Therapeutic Target in Desmoplastic Small Round Cell Sarcoma
The Androgen Receptor: A Therapeutic Target in Desmoplastic Small Round Cell Sarcoma Open
Desmoplastic small round cell tumor (DSRCT) is an aggressive, usually incurable sarcoma subtype that predominantly occurs in post-pubertal young males. Recent evidence suggests that the androgen receptor (AR) can promote tumor progression …
View article: Modelling and Daisy Chaining Control Allocation of a Multirotor Helicopter with a Single Tilting Rotor
Modelling and Daisy Chaining Control Allocation of a Multirotor Helicopter with a Single Tilting Rotor Open
This paper presents the development and implementation of a single tilting rotor multirotor helicopter. A single tilting rotor multirotor helicopter is proposed that allows for decoupled lateral acceleration and attitude states. A dynamics…