Robert M. Hughes
YOU?
Author Swipe
View article: Living through the heat: How urban children and young people experience and envision healthier cities
Living through the heat: How urban children and young people experience and envision healthier cities Open
Climate change is driving more frequent and intense heatwaves, posing growing risks to urban populations, particularly children and young people (CYP). This study examined how heatwaves affect the health, well-being, and daily lives of CYP…
View article: Zooplankton species indicate water quality and land use changes in Amazonian streams and ponds
Zooplankton species indicate water quality and land use changes in Amazonian streams and ponds Open
View article: The climate change crisis: A call for action by Past Presidents of the American Fisheries Society
The climate change crisis: A call for action by Past Presidents of the American Fisheries Society Open
We, AFS Past Presidents, assert human- caused climate change must be combatted now if we wish to conserve the world’s aquatic ecosystems and fisheries. Failing to respond to efforts restricting climate change research, scientific knowledge…
View article: The Influence of Spatial Extent and Distance on Macroinvertebrate‐Environment Relationships in Conterminous <scp>USA</scp> Stream Sites
The Influence of Spatial Extent and Distance on Macroinvertebrate‐Environment Relationships in Conterminous <span>USA</span> Stream Sites Open
Aim The relationships between environmental variables and macroinvertebrate assemblages depend on spatial extent, but the relative importance of local and regional factors remains unclear. Understanding these scale‐dependent relationships …
View article: Charting a course for freshwater biomonitoring: The grand challenges identified by the global scientific community
Charting a course for freshwater biomonitoring: The grand challenges identified by the global scientific community Open
View article: The longitudinal gradient prevails over local characteristics in shaping fish species distributions in a large neotropical reservoir
The longitudinal gradient prevails over local characteristics in shaping fish species distributions in a large neotropical reservoir Open
View article: Key Landscape Factors Influencing Stream Physical Habitats Across the Brazilian Neotropical Savanna
Key Landscape Factors Influencing Stream Physical Habitats Across the Brazilian Neotropical Savanna Open
Improved management of small headwater streams in the Cerrado (Neotropical Savanna) biome in Brazil is necessary given the significant landscape transformations caused by anthropogenic activities in recent decades. Thus, we aimed to determ…
View article: A new predictive model (MINASPACS) for spatially extensive biological assessments of southeastern Brazilian streams
A new predictive model (MINASPACS) for spatially extensive biological assessments of southeastern Brazilian streams Open
View article: Unconventional Nanopatterning Techniques for Gold Nanostructures
Unconventional Nanopatterning Techniques for Gold Nanostructures Open
View article: The impacts of alien species on river bioassessment
The impacts of alien species on river bioassessment Open
The extent of alien taxa impacts on river ecosystem health is unclear, but their frequency continues to rise. We investigated 1) the prevalence of including alien taxa in common bioindicators used in river bioassessment, 2) the effect of a…
View article: Waterbody connectivity: Linking science and policy for improved waterbody protection
Waterbody connectivity: Linking science and policy for improved waterbody protection Open
Connectivity—the flows and exchanges of organisms, materials, and energy within and among watersheds—is a central paradigm in ecosystem science. Changes in those connections have consequences for ecosystem functioning and water quality dow…
View article: City bug, country bug: How do benthic macroinvertebrate assemblages respond to an urbanization gradient taxonomically and functionally?
City bug, country bug: How do benthic macroinvertebrate assemblages respond to an urbanization gradient taxonomically and functionally? Open
View article: Striving for consistency in a national lake assessment: Defining reference status and littoral macroinvertebrate condition in lakes across the conterminous United States
Striving for consistency in a national lake assessment: Defining reference status and littoral macroinvertebrate condition in lakes across the conterminous United States Open
Benthic macroinvertebrates are widely used for assessing lotic ecosystems, however, their use in assessing lake condition has been more limited-especially at large, continental extents. We used data collected during the U.S. EPA's National…
View article: Monitoring and Conservation of Freshwater and Marine Fishes: Synopsis
Monitoring and Conservation of Freshwater and Marine Fishes: Synopsis Open
Globally, native migratory and resident fishes are declining from aquatic and terrestrial ecosystem degradation resulting from physicochemical habitat alteration, migration barriers, over-exploitation, hatchery supplementation, non-native …
View article: Habitat Diversity Mitigates the Impacts of Human Pressure on Stream Biodiversity
Habitat Diversity Mitigates the Impacts of Human Pressure on Stream Biodiversity Open
Recent decades have witnessed substantial changes in freshwater biodiversity worldwide. Although research has shown that freshwater biodiversity can be shaped by changes in habitat diversity and human‐induced pressure, the potentials for i…
View article: Environmental impact assessments should include rigorous scientific peer review
Environmental impact assessments should include rigorous scientific peer review Open
Twenty USA states or jurisdictions and 125 nations have modeled national environmental policies after the National Environmental Policy Act. That act mandates that federal agencies initiate environmental impact statements (EISs) when subst…
View article: Habitat complexity mediates the impacts of human land-use on stream biodiversity
Habitat complexity mediates the impacts of human land-use on stream biodiversity Open
Urban and cropland intensifications are persistent drivers of declines in biodiversity globally. Yet, it is poorly understood how habitat complexity can mitigate the negative impacts of such human pressures. Using a comprehensive dataset o…
View article: Predicting climate heating impacts on riverine fish species diversity in a biodiversity hotspot region
Predicting climate heating impacts on riverine fish species diversity in a biodiversity hotspot region Open
Co-occurring biodiversity and global heating crises are systemic threats to life on Earth as we know it, especially in relatively rare freshwater ecosystems, such as in Iran. Future changes in the spatial distribution and richness of 131 r…
View article: Science to support conservation action in a large river system: The Willamette River, Oregon, USA
Science to support conservation action in a large river system: The Willamette River, Oregon, USA Open
Management and conservation efforts that support the recovery and protection of large rivers are daunting, reflecting the complexity of the challenge and extent of effort (in terms of policy, economic investment, and spatial extent) needed…
View article: Global concerns related to water biology and security: The need for language and policies that safeguard living resources versus those that dilute scientific knowledge
Global concerns related to water biology and security: The need for language and policies that safeguard living resources versus those that dilute scientific knowledge Open
Increasingly, scientists and non-scientists, especially employees of government agencies, tend to use weak or
\nequivocal language when making statements related to science policy and governmental regulation. We use recent
\npublications t…
View article: Tropical and subtropical streams: A synthesis
Tropical and subtropical streams: A synthesis Open
Tropical and sub-tropical streams harbor great biodiversity and are responsible for crucial ecosystem services. Intending to contribute to the understanding of how anthropogenic stressors and pressures alter functional or taxonomic diversi…
View article: Supplementary Tables S2-4 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer
Supplementary Tables S2-4 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer Open
Supplementary Table S2 shows bivariate and multivariable analyses of germline ASPN D13/14 compared to ASPN D13/13 for lymph node involvement and metastatic recurrence. Supplementary Table S3 show bivariate analyses of ASPN D genotypes/alle…
View article: Supplementary Figure S4. from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer
Supplementary Figure S4. from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer Open
ASPN expression is associated with biochemical recurrence and metastatic recurrence.
View article: Combined Supplementary Data from FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models
Combined Supplementary Data from FS222, a CD137/PD-L1 Tetravalent Bispecific Antibody, Exhibits Low Toxicity and Antitumor Activity in Colorectal Cancer Models Open
All supplementary figures and tables within one powerpoint document
View article: Supplementary Tables S2-4 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer
Supplementary Tables S2-4 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer Open
Supplementary Table S2 shows bivariate and multivariable analyses of germline ASPN D13/14 compared to ASPN D13/13 for lymph node involvement and metastatic recurrence. Supplementary Table S3 show bivariate analyses of ASPN D genotypes/alle…
View article: Supplementary Figure S3. from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer
Supplementary Figure S3. from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer Open
ASPN expression is elevated in PCAFs.
View article: Supplementary Materials and Methods from Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression
Supplementary Materials and Methods from Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression Open
Supplementary Materials and Methods
View article: Supplementary Table S1 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer
Supplementary Table S1 from Germline Variants in Asporin Vary by Race, Modulate the Tumor Microenvironment, and Are Differentially Associated with Metastatic Prostate Cancer Open
Frequency of germline ASPN D-repeat-length in JHH prostate cancer cases and controls.
View article: Supplementary Figure S3. The tumor microenvironment in Sparcl1-/- models. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Supplementary Figure S3. The tumor microenvironment in Sparcl1-/- models. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression Open
Supplementary Figure S3
View article: Supplementary Figure S4. SPARCL1 inhibits cytoskeletal remodeling. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Supplementary Figure S4. SPARCL1 inhibits cytoskeletal remodeling. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression Open
Supplementary Figure S4