Robert S. Lee
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View article: Insulin regulates POMC neuronal plasticity to control glucose metabolism
Insulin regulates POMC neuronal plasticity to control glucose metabolism Open
Hypothalamic neurons respond to nutritional cues by altering gene expression and neuronal excitability. The mechanisms that control such adaptive processes remain unclear. Here we define populations of POMC neurons in mice that are activat…
View article: Timing of surgery and radiotherapy in the management of metastatic spine disease: expert opinion
Timing of surgery and radiotherapy in the management of metastatic spine disease: expert opinion Open
There appeared to be no significant difference in practice with the use of stereotactic radiotherapy though surgeons tend to accept a shorter interval in this subset of patients. We recommend that the interval between radiotherapy and surg…
View article: TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding
TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding Open
Insulin regulates glucose metabolism by eliciting effects on peripheral tissues as well as the brain. Insulin receptor (IR) signaling inhibits AgRP-expressing neurons in the hypothalamus to contribute to the suppression of hepatic glucose …
View article: Statement of Retraction. Hepatic Glucagon Action Is Essential for Exercise-Induced Reversal of Mouse Fatty Liver. Diabetes 2011;60:2720–2729. DOI: 10.2337/db11-0455
Statement of Retraction. Hepatic Glucagon Action Is Essential for Exercise-Induced Reversal of Mouse Fatty Liver. Diabetes 2011;60:2720–2729. DOI: 10.2337/db11-0455 Open
The corresponding author wishes to retract the above-listed article. Representative Western blots in Fig. 4 K were previously published as independent …
View article: Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-μ knockout mice
Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-μ knockout mice Open
Nitric oxide influences intramuscular signaling that affects skeletal muscle glucose uptake during exercise. The role of the main NO-producing enzyme isoform activated during skeletal muscle contraction, neuronal nitric oxide synthase-μ (n…