Robert S. Sheldon
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View article: A Community-Based Trial of Commercially Available Compression Tights in Patients With Postural Orthostatic Tachycardia Syndrome
A Community-Based Trial of Commercially Available Compression Tights in Patients With Postural Orthostatic Tachycardia Syndrome Open
Commercially available compression tights reduced heart rate and symptoms both acutely and after several hours of use. This additional benefit persisted whether concomitant medications were used. (Compression Garments in the Community With…
View article: Symptoms of postural orthostatic tachycardia syndrome in pregnancy: a cross‐sectional, community‐based survey
Symptoms of postural orthostatic tachycardia syndrome in pregnancy: a cross‐sectional, community‐based survey Open
Objective To evaluate the relationship between postural orthostatic tachycardia syndrome (POTS) and pregnancy. Design Cross‐sectional survey. Setting International. Sample A total of 8941 female patients with a diagnosis of POTS. Methods D…
View article: An Adaptive Management Framework Concept for the Sustainable Use of the Saker Falcon
An Adaptive Management Framework Concept for the Sustainable Use of the Saker Falcon Open
The Saker Falcon (Falco cherrug) is listed on the International Union for Conservation of Nature (IUCN) Red List as Globally Endangered. It breeds across continental middle latitudes, with its range spanning over 7,000 km from Central Euro…
View article: Syncope recurrence and long-term heart rate variability after cardioneuroablation for vasovagal syncope: a systematic review and meta-analysis
Syncope recurrence and long-term heart rate variability after cardioneuroablation for vasovagal syncope: a systematic review and meta-analysis Open
Background Cardioneuroablation (CNA) has emerged as a promising therapy in patients with refractory vasovagal syncope (VVS). Well-designed randomized clinical trials (RCT) are lacking. Purpose To provide an estimate of the procedural succe…
View article: Patients with POTS fear that data on abnormal haemodynamic physiology have been ignored
Patients with POTS fear that data on abnormal haemodynamic physiology have been ignored Open
Journal Article Patients with POTS fear that data on abnormal haemodynamic physiology have been ignored Get access Kate M Bourne, Kate M Bourne Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB,…
View article: A Cost-Utility Analysis of the Syncope: Pacing or Recording in The Later Years (SPRITELY) Trial
A Cost-Utility Analysis of the Syncope: Pacing or Recording in The Later Years (SPRITELY) Trial Open
The PM strategy was dominant-that is, less costly and estimated to result in a greater number of QALYs. For patients with unexplained syncope, bifascicular block, and age > 50 years, a PM is more likely to be cost-effective than an ICM.
View article: Effector mechanisms in the baroreceptor control of blood pressure
Effector mechanisms in the baroreceptor control of blood pressure Open
While the effects of changing heart rate and systemic vascular resistance have been generally understood and appreciated, the effects of changes in left ventricular contractility on end-systolic volume may have been less understood and app…
View article: Midodrine for the prevention of vasovagal syncope: a systematic review and meta-analysis
Midodrine for the prevention of vasovagal syncope: a systematic review and meta-analysis Open
Aims Vasovagal syncope (VVS) is a common clinical condition that lacks effective medical therapies despite being associated with significant morbidity. Current guidelines suggest that midodrine, a prodrug for an α1-adrenergic receptor agon…
View article: Symptom Presentation and Access to Medical Care in Patients With Postural Orthostatic Tachycardia Syndrome: Role of Sex
Symptom Presentation and Access to Medical Care in Patients With Postural Orthostatic Tachycardia Syndrome: Role of Sex Open
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily impacts female patients of childbearing age. The role of sex differences in POTS is not well understood. We sought to …
View article: Modeling Peer Selection and Influence in Youth Social Networks: A Case Study for U.S. Marine Corps Recruiting and Training
Modeling Peer Selection and Influence in Youth Social Networks: A Case Study for U.S. Marine Corps Recruiting and Training Open
Youth currently entering the job market are part of Generation Z. Research suggests that this generation is different from others in their values and life priorities and will challenge organizations who wish to attract, develop, and retain…
View article: Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss
Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss Open
Background Postural orthostatic tachycardia syndrome (POTS) is a debilitating form of chronic orthostatic intolerance that primarily affects women and causes substantial impairment in quality of life and function. Yet, there is minimal lit…
View article: Low-blood pressure phenotype underpins the tendency to reflex syncope
Low-blood pressure phenotype underpins the tendency to reflex syncope Open
Background: We hypothesized that cardiovascular physiology differs in reflex syncope patients compared with the general population, predisposing such individuals to vasovagal reflex. Methods: In this multicohort cross-sectional study, we c…
View article: Low blood pressure phenotype underpins the tendency to reflex syncope
Low blood pressure phenotype underpins the tendency to reflex syncope Open
BACKGROUND We hypothesized that cardiovascular physiology differs in reflex syncope patients compared with general population, predisposing such subjects to vasovagal reflex. METHODS In this multicohort cross-sectional study, we compared r…
View article: Frequency of injuries associated with syncope in the prevention of syncope trials
Frequency of injuries associated with syncope in the prevention of syncope trials Open
Aims Syncope can lead to injuries. We determined the frequency, severity, and predictors of injuries due to syncope in cohorts of syncope patients. Methods and results Participants were enrolled in the POST2 (fludrocortisone) and POST4 (mi…
View article: The Search for the Genes of Vasovagal Syncope
The Search for the Genes of Vasovagal Syncope Open
Only humans faint, and not all do so. Syncope tends to recur, and the predisposition to syncope can persist over many decades. Observations such as these have suggested that there may be a genetic predisposition to vasovagal syncope. It se…