Explanipedia

First Investigation of a Eustachian Tube Stent in Experimentally Induced Eustachian Tube Dysfunction Open

Katharina Schmitt, Malena Timm, Philipp Krüger, Niels Oppel, Alexandra Napp , et al. · 2024

Unmet needs in the treatment of chronic otitis media and Eustachian tube dysfunction (ETD) triggered the development of stents for the Eustachian tube (ET). In this study, for the first time, stents were placed in an artificially blocked E…

Long-Term Preclinical Evaluation of a Permanent Stent Developed for the Human Eustachian Tube Open

Katharina Schmitt, Malena Timm, Philipp Krüger, Niels Oppel, Alexandra Napp , et al. · 2024

The Eustachian tube (ET) is a bottleneck when it comes to middle ear (ME) health. If its function is impaired, this can lead to serious consequences for the patient, such as hearing problems or deafness. Therefore, this study investigated …

Investigation of Stent Prototypes for the Eustachian Tube in Human Donor Bodies Open

Lena Rosenbusch, Robert Schuon, T Wilfling, Philipp Krüger, Kerstin Lebahn , et al. · 2023

Chronic otitis media is often connected to Eustachian tube dysfunction. As successful treatment cannot be guaranteed with the currently available options, the aim is to develop a stent for the Eustachian tube (ET). Over the course of this …

Functional cleft palate surgery Open

U. Joos, A.F. Markus, Robert Schuon · 2023

Intravascular Ultrasonography (IVUS)—A Tool for Imaging the Eustachian Tube? Open

Niels Oppel, Gerrit Paasche, André Bleich, Thomas Lenarz, Robert Schuon · 2022

The Eustachian tube (ET) has a key role in the pathogenesis of otitis media. Until now, there has been a lack of meaningful imaging methods to investigate the ET and its surrounding tissue. The aim of the current study was to investigate t…

A new method for OCT Imaging of the Eustachian tube Open

Axel Boese, Holger Fritzsche, Gerrit Paasche, Thomas Lenarz, Robert Schuon · 2022

For treatment decision of Eustachian tube (ET) dysfunction, a reliable diagnosis of the reason for this dysfunction is of interest. Imaging methods like CT or MRI do not show enough details today. Endoscopy is challenging but can show at l…

Development of an In Vivo Model for Eustachian Tube Dysfunction Open

Niels Oppel, Malena Ezzat, Philipp Krüger, Katharina Schmitt, Alexandra Napp , et al. · 2022

Otitis media is often connected to Eustachian tube dysfunction (ETD). Until now, there was no large animal model available for the examination of new treatment methods such as stents for the Eustachian tube (ET). Thus, the aim of the study…

Cone beam CT with different prototypes of an Eustachian tube stent Open

Malena Ezzat, Gerrit Paasche, Philipp Krüger, Tobias Stein, K Schümann , et al. · 2022

Stenting the Eustachian tube (ET) might provide a new approach to treat obstructive ET dysfunction. Stents have to be positioned properly in the cartilaginous part of the ET. To control position of the stent after insertion, cone beam CT (…

Functional aspects of the Eustachian tube by means of 3D-modeling Open

Robert Schuon, Josef Schwarzensteiner, Gerrit Paasche, Thomas Lenarz, Samuel John · 2021

The extent of dysfunction of the Eustachian tube (ET) is relevant in understanding the pathogenesis of secondary otological diseases such as acute or chronic otitis media. The underlying mechanism of ET dysfunction remains poorly understoo…

Functional Aspects of the Eustachian Tube by Means of 3D-Modeling Open

Robert Schuon, Josef Schwarzensteiner, Gerrit Paasche, Thomas Lenarz, Samuel John · 2020

The extent of dysfunction of the Eustachian tube (ET) is relevant in understanding the pathogenesis of secondary otological diseases such as acute or chronic otitis media. The underlying mechanism of ET dysfunction remains poorly understoo…

Polymeric stents for the Eustachian tube: development and human cadaver study Open

K Schümann, T Wilfling, Gerrit Paasche, Robert Schuon, Thomas Lenarz , et al. · 2020

Impairment of Eustachian tube function with nonsufficient ventilation of the middle ear is a main cause for chronic otitis media. To provide an effective and safe therapy, the innovative concept of Eustachian tube stenting was established.…

Dimensions and position of the Eustachian tube in Humans Open

Ida Janzen-Senn, Robert Schuon, Frank Tavassol, Thomas Lenarz, Gerrit Paasche · 2020

Eustachian tube (ET) dysfunction is one of the causes for chronic otitis media. To develop new therapies such as stents to facilitate middle ear ventilation, a better knowledge on dimensions and positions of the ET in individual patients i…

Simulating an Eustachian Tube Dysfunktion in Sheep’s head cadaver Open

T Wilfling, Paul Krüger, Gerrit Paasche, Todd Stein, Mahmoud Ezzat , et al. · 2020

Introduction The Eustachian Tube (ET) is an organ that connects the nasopharynx with the middle ear cavity, whereas its primary function is the physiological regulation of pressure in the tympanum and drainage of mucous.

Implementierung einer simulierten Tubenventilationsstörung im Schafskopf Kadaver Open

T Wilfling, P Krüger, Gerrit Paasche, T Stein, Malena Ezzat , et al. · 2020

Einleitung Die Eustachische Röhre (ER) ist ein Organ das den Nasenrachen mit dem Mittelohr verbindet und physiologischer weise den Druckausgleich in der Pauke reguliert sowie Sekret daraus abtransportiert. Die Autoren unterschiedlicher Pub…

Eustachian tube stents – direct and indirect findings in CBCT Open

Robert Schuon, Thomas Lenarz, Gerrit Paasche, T Wilfling, Niels Grabow , et al. · 2019

Stenting of the Eustachian tube offers a possibility to decrease the opening resistance of the tube. Coming from balloon tuboplasty a catheter-based application has been developed. The goal of the study was to evaluate direct and indirect …

Stent-Therapie der Tuba Eustachii – Direkte und indirekte Merkmale im CBCT Open

Robert Schuon, Thomas Lenarz, G Paasche, T Wilfling, Niels Grabow , et al. · 2019

Die Stent-Therapie der Tuba Eustachii bietet einen möglichen Ansatz zum Herabsetzen des Tubenöffnungswiderstands. Aus der Erfahrung mit der Ballondilatation der Tube wurde eine katheterbasierte Applikation entwickelt. Inwieweit die Einlage…

Age dependent changes of the Eustachian tube Open

Gerrit Paasche, Ida Janzen-Senn, Frank Tavassol, Thomas Lenarz, Robert Schuon · 2019

To develop stents for the Eustachian tube (ET) to treat middle ear ventilation disorders, a better knowledge about anatomical variations is necessary. Stents have to be places atraumatically and shall not induce a permanently open ET.

Stent-Therapie der Eustachischen Röhre (ER) – Ein neues, innovatives Behandlungskonzept zur Therapie chronischer Mittelohrerkrankungen – Machbarkeitsuntersuchung am Humanen Präparat Open

T Wilfling, Robert Schuon, Gerrit Paasche, T Stein, Klaus Schümann , et al. · 2019

Die Dysfunktion der Eustachischen Röhre (ER) ist einer der zugrunde liegende Pathomechanismen von chronischen Mitteloherkrankungen. Die Fehlfunktion wird im knorpeligen Anteil der ER beschrieben. Unterschiedliche Behandlungskonzepte (Tuben…

Stenting the Eustachian Tube – a New Innovative Treatmentconcept for Chronic Otitis Media – Feasibility Study on Fresh Human Cadavers Open

T Wilfling, Robert Schuon, Gerrit Paasche, Thomas Stein, K Schümann , et al. · 2019

Impaired function of the Eustachian tube (ET) is the main underlying pathophysiology of chronic otitis media. The dysfunction is typically located in the cartilaginous part of the ET.

Stenting the Eustachian tube to treat chronic otitis media - a feasibility study in sheep Open

Friederike Pohl, Robert Schuon, Felicitas Miller, Andreas Kampmann, Eva Bültmann , et al. · 2018

Stenting of the Eustachian tube was successfully transferred from cadaver studies to an in-vivo application without complications. The stent was well tolerated, the middle ears were ventilated, and clearance of the auditory tube appeared p…

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