Robert V. Moquin
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View article: Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P<sub>1</sub>): Discovery and SAR of a Novel Isoxazole Based Series
Potent and Selective Agonists of Sphingosine 1-Phosphate 1 (S1P<sub>1</sub>): Discovery and SAR of a Novel Isoxazole Based Series Open
Sphingosine 1-phosphate (S1P) is the endogenous ligand for the sphingosine 1-phosphate receptors (S1P1-5) and evokes a variety of cellular responses through their stimulation. The interaction of S1P with the S1P receptors plays a fundament…