Robert W. Hu
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View article: Survival and treatment in older patients with ewing sarcoma: an analysis of the national cancer database
Survival and treatment in older patients with ewing sarcoma: an analysis of the national cancer database Open
Background Ewing sarcoma (EWS) is a malignancy which primarily arises in adolescence and has been studied extensively in this population. Much less is known about the rare patient cohort over the age of 40 at diagnosis. In this study, we d…
View article: Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia
Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia Open
Preeclampsia is the most common placental pathology in pregnant females, with increased morbidity and mortality incurred on the mother and the fetus. There is a need for improved biomarkers for diagnosis and monitoring of this condition. P…
View article: Circulating exosomes derived from transplanted progenitor cells aid the functional recovery of ischemic myocardium
Circulating exosomes derived from transplanted progenitor cells aid the functional recovery of ischemic myocardium Open
Liquid biopsy of circulating exosomes can be used to monitor recovery of ischemic myocardium after transplanting cardiac progenitor cells.
View article: Noninvasive diagnosis of recurrent autoimmune type 1 diabetes after islet cell transplantation
Noninvasive diagnosis of recurrent autoimmune type 1 diabetes after islet cell transplantation Open
Islet cell transplantation is curative therapy for patients with complicated autoimmune type 1 diabetes (T1D). We report the diagnostic potential of circulating transplant islet-specific exosomes to noninvasively distinguish pancreatic β c…
View article: Curcumin in Hepatobiliary Disease: Pharmacotherapeutic Properties and Emerging Potential Clinical Applications
Curcumin in Hepatobiliary Disease: Pharmacotherapeutic Properties and Emerging Potential Clinical Applications Open
Curcumin, an aromatic phytoextract from the turmeric (Curcuma longa) rhizome, has been used for centuries for a variety of purposes, not the least of which is medicinal. A growing body of evidence suggests that curcumin has a broad range o…
View article: HDAC3 mediates smoking-induced pancreatic cancer
HDAC3 mediates smoking-induced pancreatic cancer Open
Smoking is a major risk factor for developing pancreatic adenocarcinoma (PDAC); however, little is known about the mechanisms involved. Here we employed a genetic animal model of early stages of PDAC that overexpresses oncogenic Kras in th…