Robert B. Wallace
YOU?
Author Swipe
View article: The Relationship between Occupation and Lung Cancer Incidence in the Women’s Health Initiative Observational Study
The Relationship between Occupation and Lung Cancer Incidence in the Women’s Health Initiative Observational Study Open
Background. Lung cancer remains the foremost cause of cancer mortality among US women, with a notable proportion arising in never-smokers. While occupational exposures contribute to lung cancer risk, women have been underrepresented in occ…
View article: Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles
Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles Open
Objective The Apolipoprotein ( APOE ) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular …
View article: Racial/Ethnic Disparities in Alzheimer’s Disease Risk: Role of Exposure to Ambient Fine Particles
Racial/Ethnic Disparities in Alzheimer’s Disease Risk: Role of Exposure to Ambient Fine Particles Open
BACKGROUND: Whether racial/ethnic disparities in Alzheimer's disease (AD) risk may be explained by ambient fine particles (PM2.5) has not been studied. METHOD: We conducted a prospective, population-based study on a cohort of Black (n = 48…
View article: Genetic interleukin-6 receptor blockade, chronic disease risk and longevity
Genetic interleukin-6 receptor blockade, chronic disease risk and longevity Open
Introduction Interleukin-6 (IL-6) levels have been related to increased risk of chronic disease and mortality (1-5). Whether genetic IL-6 receptor (IL6R) blockade is associated with lower chronic disease risk or greater longevity is unknow…
View article: Epigenetic entropy, social disparity, and health and lifespan in the Women’s Health Initiative
Epigenetic entropy, social disparity, and health and lifespan in the Women’s Health Initiative Open
The pace of aging varies between individuals and is marked by changes in DNA methylation (DNAm) including an increase in randomness or entropy. Here, we computed epigenetic scores of aging and entropy using DNAm datasets from the Women’s H…
View article: Pathways From Socioeconomic Factors to Major Cardiovascular Events Among Postmenopausal Veteran and Nonveteran Women: Findings From the Women's Health Initiative
Pathways From Socioeconomic Factors to Major Cardiovascular Events Among Postmenopausal Veteran and Nonveteran Women: Findings From the Women's Health Initiative Open
Background Cardiovascular disease (CVD) remains a leading cause of death for women in the United States, with veterans being at potentially higher risk than their nonveteran counterparts due to accelerated aging and distinct biopsychosocia…
View article: Secondary causal mediation analysis of a pragmatic clinical trial to evaluate the effect of chiropractic care for US active-duty military on biopsychosocial outcomes occurring through effects on low back pain interference and intensity
Secondary causal mediation analysis of a pragmatic clinical trial to evaluate the effect of chiropractic care for US active-duty military on biopsychosocial outcomes occurring through effects on low back pain interference and intensity Open
Objective We evaluate change in low back pain (LBP) intensity and interference as the mechanism by which chiropractic care affects other biopsychosocial factors in US active-duty military members. Design We conducted secondary, exploratory…
View article: Effect of chiropractic care on low back pain for active-duty military members: Mediation through biopsychosocial factors
Effect of chiropractic care on low back pain for active-duty military members: Mediation through biopsychosocial factors Open
This study evaluates biopsychosocial factors as mediators of the effect of chiropractic care on low back pain (LBP) intensity and interference for active-duty military members. Data from a multi-site, pragmatic clinical trial comparing six…
View article: Investigating Predictors of Preserved Cognitive Function in Older Women Using Machine Learning: Women's Health Initiative Memory Study
Investigating Predictors of Preserved Cognitive Function in Older Women Using Machine Learning: Women's Health Initiative Memory Study Open
Background: Identification of factors that may help to preserve cognitive function in late life could elucidate mechanisms and facilitate interventions to improve the lives of millions of people. However, the large number of potential fact…
View article: Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease
Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease Open
Among postmenopausal women with IBD, risk of ischemic stroke may be higher than in non-IBD women.
View article: Stressful life events, social support, and epigenetic aging in the Women's Health Initiative
Stressful life events, social support, and epigenetic aging in the Women's Health Initiative Open
Background Elevated psychosocial stress has been linked with accelerated biological aging, including composite DNA methylation (DNAm) markers that predict aging‐related outcomes (“epigenetic age”). However, no study has examined whether st…
View article: Hemodynamic Confirmation of Peripheral Pulmonary Stenosis Caused by Aortic Dissection
Hemodynamic Confirmation of Peripheral Pulmonary Stenosis Caused by Aortic Dissection Open
In aortic dissection, the intimal and medial tear most commonly is located in the ascending aorta. The ascending aorta and pulmonary trunk have a common adventitia, and therefore dissection into the adventitia of the ascending aorta common…
View article: Massive Calcification of a Porcine Bioprosthesis in the Aortic Valve Position and the Role of Calcium Supplements
Massive Calcification of a Porcine Bioprosthesis in the Aortic Valve Position and the Role of Calcium Supplements Open
The development of calcific deposits in porcine aortic valve cusps used in bioprostheses for cardiac valve replacement in humans is well recognized. Often the calcific deposits cause tearing of the porcine aortic valve cusps and the tearin…
View article: Acquired Cor Triatriatum (Left Ventricular False Aneurysm)
Acquired Cor Triatriatum (Left Ventricular False Aneurysm) Open
Cor triatriatum is a congenital anomaly in which the left atrium (LA) is essentially partitioned into two chambers with a small orifice between them. The cephalad chamber receives the pulmonary veins and the caudal chamber is connected to …
View article: Association of macular pigment optical density with retinal layer thicknesses in eyes with and without manifest primary open-angle glaucoma
Association of macular pigment optical density with retinal layer thicknesses in eyes with and without manifest primary open-angle glaucoma Open
Objective To investigate associations between baseline macular pigment optical density (MPOD) and retinal layer thicknesses in eyes with and without manifest primary open-angle glaucoma (POAG) in the Carotenoids in Age-Related Eye Disease …
View article: Preterm birth, birthweight, and subsequent risk for depression
Preterm birth, birthweight, and subsequent risk for depression Open
An individual’s birthweight, a marker of in utero exposures, was recently associated with certain psychiatric conditions. However, studies investigating the relationship between an individual’s preterm birth status and/or birthweight and r…
View article: The Scottish Medical Imaging Archive: 57.3 Million Radiology Studies Linked to Their Medical Records
The Scottish Medical Imaging Archive: 57.3 Million Radiology Studies Linked to Their Medical Records Open
Keywords: MRI, Imaging Sequences, Ultrasound, Mammography, CT, Angiography, Conventional Radiography Published under a CC BY 4.0 license. See also the commentary by Whitman and Vining in this issue.
View article: Association of type 2 diabetes mellitus with dementia‐related and non–dementia‐related mortality among postmenopausal women: A secondary competing risks analysis of the women's health initiative
Association of type 2 diabetes mellitus with dementia‐related and non–dementia‐related mortality among postmenopausal women: A secondary competing risks analysis of the women's health initiative Open
INTRODUCTION Alzheimer's disease (AD) and AD‐related dementias (ADRD) are leading causes of death among older adults in the United States. Efforts to understand risk factors for prevention are needed. METHODS Participants ( n = 146,166) en…
View article: Association Between the Healthy Lifestyle Index and Risk of Multimorbidity in the Women’s Health Initiative
Association Between the Healthy Lifestyle Index and Risk of Multimorbidity in the Women’s Health Initiative Open
Background Multimorbidity, defined as the presence of 2 or more chronic health conditions, is increasingly common among older adults. The combination of lifestyle characteristics such as diet quality, smoking status, alcohol intake, physic…
View article: Cognitive Function and Changes in Cognitive Function as Predictors of Incident Cardiovascular Disease: The Women's Health Initiative Memory Study
Cognitive Function and Changes in Cognitive Function as Predictors of Incident Cardiovascular Disease: The Women's Health Initiative Memory Study Open
Background Cognitive impairment and decline may signal the increased risk of incident cardiovascular disease (CVD). We examined associations of global cognitive function, as measured by the Modified Mini-Mental State Examination (3MS) and …