Roberta Bilardo
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View article: N-isopropylacrylamide based nanogels crossing the blood-brain barrier: evidence of high in vitro internalization in human endothelial cells and in vivo permeation in zebrafish
N-isopropylacrylamide based nanogels crossing the blood-brain barrier: evidence of high in vitro internalization in human endothelial cells and in vivo permeation in zebrafish Open
The development of effective neurological treatments remains a challenge due to the low permeation across the blood-brain barrier (BBB). The use of nanoparticles for brain drug delivery is promising, but the level of BBB crossing remains l…
View article: N-isopropylacrylamide based nanogels crossing the blood-brain barrier: evidence of high in vitro internalization in human endothelial cells and in vivo permeation in zebrafish
N-isopropylacrylamide based nanogels crossing the blood-brain barrier: evidence of high in vitro internalization in human endothelial cells and in vivo permeation in zebrafish Open
The development of effective neurological treatments remains a challenge due to the low permeation across the blood-brain barrier (BBB). The use of nanoparticles for brain drug delivery is promising, but the level of BBB crossing remains l…
View article: The Role of Crosslinker Content of Positively Charged NIPAM Nanogels on the In Vivo Toxicity in Zebrafish
The Role of Crosslinker Content of Positively Charged NIPAM Nanogels on the In Vivo Toxicity in Zebrafish Open
Polymeric nanogels as drug delivery systems offer great advantages, such as high encapsulation capacity and easily tailored formulations; however, data on biocompatibility are still limited. We synthesized N-isopropylacrylamide nanogels, w…
View article: Influence of surface chemistry and morphology of nanoparticles on protein corona formation
Influence of surface chemistry and morphology of nanoparticles on protein corona formation Open
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in response to the demand for better therapeutics and diagnostics. However, the limited understanding of the interaction between nanoparticles and biologic…
View article: A Triple Culture Cell System Modeling the Human Blood-Brain Barrier
A Triple Culture Cell System Modeling the Human Blood-Brain Barrier Open
The delivery of drugs to the brain remains a challenge due to the blood-brain barrier's (BBB) highly specific and restrictive properties, which controls and restrict access to the brain parenchyma. However, with the development of nanotech…