Roberta Colicchio
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View article: Antibiofilm sustainable strategies: pomegranate extract from agri-food waste as a natural antifungal against emerging Candida pathogens
Antibiofilm sustainable strategies: pomegranate extract from agri-food waste as a natural antifungal against emerging Candida pathogens Open
Introduction Candida spp. infections are a leading cause of morbidity, particularly among immunocompromised and hospitalized patients. Their pathogenicity is driven by multiple virulence factors, including dimorphic transitions, germ tube …
View article: <i>In Vitro</i> Properties of WMRK-gH625, a Novel Hybrid Peptide against Multidrug-Resistant Pathogens
<i>In Vitro</i> Properties of WMRK-gH625, a Novel Hybrid Peptide against Multidrug-Resistant Pathogens Open
Antimicrobial resistance (AMR) poses a critical global health threat, driven largely by the misuse of antibiotics and the emergence of multidrug-resistant (MDR) pathogens. Antimicrobial peptides (AMPs) have emerged as promising alternative…
View article: Case Report: Uncommon presentation of Schistosoma haematobium infection in a migrant patient: diagnostic and therapeutic challenges
Case Report: Uncommon presentation of Schistosoma haematobium infection in a migrant patient: diagnostic and therapeutic challenges Open
Schistosomiasis is a parasitic infection prevalent mainly in tropical and subtropical countries. We report a case of urinary infection caused by Schistosoma haematobium in a 16 years-old boy from Mali presented to our Institution with a on…
View article: VALIDATION OF SURGICAL MASKS DURING COVID19 EMERGENCY: ACTIVITIES AT THE UNIVERSITY OF NAPOLI FEDERICO II
VALIDATION OF SURGICAL MASKS DURING COVID19 EMERGENCY: ACTIVITIES AT THE UNIVERSITY OF NAPOLI FEDERICO II Open
During COVID-19 pandemic crisis, Italian Government has approved Law Decree no. 18 of 17 march 2020, in which art. 15 allows enterprises to produce, import and commercialize surgical masks notwithstanding the current rules of product certi…
View article: Thyme Essential Oil as a Potential Tool Against Common and Re-Emerging Foodborne Pathogens: Biocidal Effect on Bacterial Membrane Permeability
Thyme Essential Oil as a Potential Tool Against Common and Re-Emerging Foodborne Pathogens: Biocidal Effect on Bacterial Membrane Permeability Open
Over the past decade, foodborne diseases have become a significant public health concern, affecting millions of people globally. Major pathogens like Salmonella spp., Escherichia coli, Listeria monocytogenes, and Staphylococcus aureus cont…
View article: <i>Pneumocystis jirovecii</i> pneumonia infections in HIV-uninfected patients hospitalized for COVID-19
<i>Pneumocystis jirovecii</i> pneumonia infections in HIV-uninfected patients hospitalized for COVID-19 Open
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View article: Neisseria meningitidis activates pyroptotic pathways in a mouse model of meningitis: role of a two-partner secretion system
Neisseria meningitidis activates pyroptotic pathways in a mouse model of meningitis: role of a two-partner secretion system Open
There is evidence that in infected cells in vitro the meningococcal HrpA/HrpB two-partner secretion system (TPS) mediates the exit of bacteria from the internalization vacuole and the docking of bacteria to the dynein motor resulting in th…
View article: Pomegranate Peel and Olive Leaf Extracts to Optimize the Preservation of Fresh Meat: Natural Food Additives to Extend Shelf-Life
Pomegranate Peel and Olive Leaf Extracts to Optimize the Preservation of Fresh Meat: Natural Food Additives to Extend Shelf-Life Open
Quality and safety are one of the main concerns of the European Union in food preservation. Using chemical additives extends the shelf-life of fresh foods but raises consumer’s concerns about the potential long-term carcinogenic effects. U…
View article: Modulation of innate immunity related genes resulting in prophylactic antimicrobial and antiviral properties
Modulation of innate immunity related genes resulting in prophylactic antimicrobial and antiviral properties Open
View article: Eco-Friendly Sanitization of Indoor Environments: Effectiveness of Thyme Essential Oil in Controlling Bioaerosol Levels and Disinfecting Surfaces
Eco-Friendly Sanitization of Indoor Environments: Effectiveness of Thyme Essential Oil in Controlling Bioaerosol Levels and Disinfecting Surfaces Open
Bioaerosols and pathogens in indoor workplaces and residential environments are the primary culprits of several infections. Techniques for sanitizing air and surfaces typically involve the use of UV rays or chemical sanitizers, which may r…
View article: Antimicrobial efficacy of Punica granatum Lythraceae peel extract against pathogens belonging to the ESKAPE group
Antimicrobial efficacy of Punica granatum Lythraceae peel extract against pathogens belonging to the ESKAPE group Open
The improper use and abuse of antibiotics have led to an increase in multidrug-resistant (MDR) bacteria resulting in a failure of standard antibiotic therapies. To date, this phenomenon represents a leading public health threat of the 21st…
View article: Deciphering the Chemical Language of the Immunomodulatory Properties of <i>Veillonella parvula</i> Lipopolysaccharide
Deciphering the Chemical Language of the Immunomodulatory Properties of <i>Veillonella parvula</i> Lipopolysaccharide Open
Veillonella parvula , prototypical member of the oral and gut microbiota, is at times commensal yet also potentially pathogenic. The definition of the molecular basis tailoring this contrasting behavior is key for broadening our understand…
View article: Vine-Winery Byproducts as Precious Resource of Natural Antimicrobials: In Vitro Antibacterial and Antibiofilm Activity of Grape Pomace Extracts against Foodborne Pathogens
Vine-Winery Byproducts as Precious Resource of Natural Antimicrobials: In Vitro Antibacterial and Antibiofilm Activity of Grape Pomace Extracts against Foodborne Pathogens Open
Grape pomace is the main by-product of vine-winery chains. It requires adequate treatment and disposal but is also an economically underused source of bioactive plant secondary metabolites. This study aimed to investigate the antibacterial…
View article: Antibacterial and Antibiofilm Efficacy of Thyme (Thymus vulgaris L.) Essential Oil against Foodborne Illness Pathogens, Salmonella enterica subsp. enterica Serovar Typhimurium and Bacillus cereus
Antibacterial and Antibiofilm Efficacy of Thyme (Thymus vulgaris L.) Essential Oil against Foodborne Illness Pathogens, Salmonella enterica subsp. enterica Serovar Typhimurium and Bacillus cereus Open
Nowadays, the wide spread of foodborne illness and the growing concerns about the use of synthetic food additives have shifted the focus of researchers towards essential oils (EOs) as possible antimicrobials and preservatives of natural or…
View article: Towards Green Strategies of Food Security: Antibacterial Synergy of Essential Oils from Thymus vulgaris and Syzygium aromaticum to Inhibit Escherichia coli and Staphylococcus aureus Pathogenic Food Isolates
Towards Green Strategies of Food Security: Antibacterial Synergy of Essential Oils from Thymus vulgaris and Syzygium aromaticum to Inhibit Escherichia coli and Staphylococcus aureus Pathogenic Food Isolates Open
Foodborne diseases continue to represent an important public health issue. The control of food spoilage and pathogenic microorganisms is achieved mainly by synthetic chemicals, unfortunately associated to several undesirable aspects. The g…
View article: Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study
Molecular Epidemiology of Genital Infections in Campania Region: A Retrospective Study Open
This study provides updated information on the prevalence and co-infections caused by genital microorganisms and pathogens: Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma parvum, Ureaplasma urealyticum, Trichomonas vaginalis, and Ga…
View article: Alcohol-Based Hand Sanitizers: Does Gelling Agent Really Matter?
Alcohol-Based Hand Sanitizers: Does Gelling Agent Really Matter? Open
Hand hygiene, social distancing, and face covering are considered the first protection against Coronavirus spreading. The high demand during the COVID-19 emergency has driven a frenetic production and marketing of hand sanitizer gels. Neve…
View article: The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221T
The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221T Open
Gram-negative bacteria experiencing marine habitats are constantly exposed to stressful conditions dictating their survival and proliferation. In response to these selective pressures, marine microorganisms adapt their membrane system to e…
View article: Microbiological Evaluation and Sperm DNA Fragmentation in Semen Samples of Patients Undergoing Fertility Investigation
Microbiological Evaluation and Sperm DNA Fragmentation in Semen Samples of Patients Undergoing Fertility Investigation Open
Fifteen percent of male infertility is associated with urogenital infections; several pathogens are able to alter the testicular and accessory glands’ microenvironment, resulting in the impairment of biofunctional sperm parameters. The pur…
View article: Estimating asymptomatic SARS-CoV-2 infections in a geographic area of low disease incidence
Estimating asymptomatic SARS-CoV-2 infections in a geographic area of low disease incidence Open
Background The SARS-CoV-2 infection has emerged as a rapidly spreading infection. Today it is relatively easy to isolate Covid-19 symptomatic cases, while remains problematic to control the disease spread by infected but symptom-free indiv…
View article: Testing Surgical Face Masks in an Emergency Context: The Experience of Italian Laboratories during the COVID-19 Pandemic Crisis
Testing Surgical Face Masks in an Emergency Context: The Experience of Italian Laboratories during the COVID-19 Pandemic Crisis Open
The first wave of the COVID-19 pandemic brought about a broader use of masks by both professionals and the general population. This resulted in a severe worldwide shortage of devices and the need to increase import and activate production …
View article: Phytocompounds vs. Dental Plaque Bacteria: In vitro Effects of Myrtle and Pomegranate Polyphenolic Extracts Against Single-Species and Multispecies Oral Biofilms
Phytocompounds vs. Dental Plaque Bacteria: In vitro Effects of Myrtle and Pomegranate Polyphenolic Extracts Against Single-Species and Multispecies Oral Biofilms Open
In the last decades, resistant microbial infection rate has dramatically increased, especially infections due to biofilm-producing strains that require increasingly complex treatments and are responsible for the increased mortality percent…
View article: The Role of Thermal Water in Chronic Skin Diseases Management: A Review of the Literature
The Role of Thermal Water in Chronic Skin Diseases Management: A Review of the Literature Open
The benefits of thermal water in different diseases have been known since ancient times. Over the past decades, a re-assessment of the use of mineral water for the treatment of several pathologic conditions has taken place around the world…
View article: Urinary Biomarkers: Diagnostic Tools for Monitoring Athletes’ Health Status
Urinary Biomarkers: Diagnostic Tools for Monitoring Athletes’ Health Status Open
Acute or intense exercise is sometimes related to infections of the urinary tract. It can also lead to incorrect hydration as well as incorrect glomerular filtration due to the presence of high-molecular-weight proteins that cause damage t…
View article: Viable microbial community composition of Agnano Thermal Spring Water
Viable microbial community composition of Agnano Thermal Spring Water Open
The Agnano thermal spring water (ATSW) is mainly a salso-bromo-iodic-bicarbonate-alkaline-sulphurous water. Since ancient time, the benefits of thermal spring water in the treatment of various diseases have been known. Today it is known th…
View article: In vitro Synergy of Polyphenolic Extracts From Honey, Myrtle and Pomegranate Against Oral Pathogens, S. mutans and R. dentocariosa
In vitro Synergy of Polyphenolic Extracts From Honey, Myrtle and Pomegranate Against Oral Pathogens, S. mutans and R. dentocariosa Open
The increasing incidence rate of oral diseases, the wide spread of antimicrobial resistance, and the adverse effects of conventional antibiotics mean alternative prevention and treatment options are needed to counteract oral pathogens. In …
View article: Methicillin-Resistant Staphylococcus aureus: Risk for General Infection and Endocarditis Among Athletes
Methicillin-Resistant Staphylococcus aureus: Risk for General Infection and Endocarditis Among Athletes Open
The first studies on Staphylococcus aureus (SA) infections in athletes were conducted in the 1980s, and examined athletes that perform in close physical contact, with particular attention to damaged or infected skin. Recent studies have us…
View article: HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes
HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes Open
Acute or strenuous exercise is sometimes related to upper respiratory tract infections in athletes. Practicing intense and regular exercise can lead to incorrect activation of the immune system, causing athletes to be excluded from trainin…
View article: Human Defensins: A Novel Approach in the Fight against Skin Colonizing Staphylococcus aureus
Human Defensins: A Novel Approach in the Fight against Skin Colonizing Staphylococcus aureus Open
Staphylococcus aureus is a microorganism capable of causing numerous diseases of the human skin. The incidence of S. aureus skin infections reflects the conflict between the host skin′s immune defenses and the S. aureus’ virulence elements…
View article: Celiac disease‐associated <i>Neisseria flavescens</i> decreases mitochondrial respiration in CaCo‐2 epithelial cells: Impact of <i>Lactobacillus paracasei</i> CBA L74 on bacterial‐induced cellular imbalance
Celiac disease‐associated <i>Neisseria flavescens</i> decreases mitochondrial respiration in CaCo‐2 epithelial cells: Impact of <i>Lactobacillus paracasei</i> CBA L74 on bacterial‐induced cellular imbalance Open
We previously identified a Neisseria flavescens strain in the duodenum of celiac disease (CD) patients that induced immune inflammation in ex vivo duodenal mucosal explants and in CaCo-2 cells. We also found that vesicular trafficking was …