Roberta Vazzana
YOU?
Author Swipe
View article: An integrated phenotypic and genomic approach to characterize MBL-producing Enterobacterales strains circulating in a Sicilian transplant center
An integrated phenotypic and genomic approach to characterize MBL-producing Enterobacterales strains circulating in a Sicilian transplant center Open
Metallo-β-lactamases (MBLs)-producing Enterobacterales infections represent a serious threat in clinical practice due to high mortality rates associated and the limited therapeutic options available. Given their increased dissemination acr…
View article: Attenuated Molecular Response to SARS-CoV-2 in MDMs Isolated from Immunosuppressed Transplanted Patients
Attenuated Molecular Response to SARS-CoV-2 in MDMs Isolated from Immunosuppressed Transplanted Patients Open
Immunosuppressive therapies used in clinics to reduce the risk of rejection in transplanted patients unfortunately also decrease the response of the immune system to the pathogens. Previous data has shown that the most diffuse SARS-CoV-2 v…
View article: Shotgun metagenomics detects the human pegivirus complete genome in a pediatric patient with acute hepatitis of unknown etiology: a case report
Shotgun metagenomics detects the human pegivirus complete genome in a pediatric patient with acute hepatitis of unknown etiology: a case report Open
Human pegivirus (HPgV) is a positive-sense, single-strand RNA virus belonging to the Flaviviridae family. Although not conclusively linked to a specific disease, an increasing number of studies have recently reported an association between…
View article: Whole-genome sequencing characterisation of a new KPC-245 variant-carrying Klebsiella pneumoniae strain isolated from a transplanted patient and resistant to ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam
Whole-genome sequencing characterisation of a new KPC-245 variant-carrying Klebsiella pneumoniae strain isolated from a transplanted patient and resistant to ceftazidime/avibactam, meropenem/vaborbactam and imipenem/relebactam Open
In our study, by using WGS analysis on a clinical isolate, we identified a new blaKPC variant within the Tn4401 transposon. Our results confirm the importance of continuous surveillance of multidrug-resistant K. pneumoniae in th…
View article: Exposure of monocyte-derived macrophages to the UV-inactivated SARS-CoV-2 VOCs shows similar effects on the transcriptomic profile as active virus: a comparative analysis
Exposure of monocyte-derived macrophages to the UV-inactivated SARS-CoV-2 VOCs shows similar effects on the transcriptomic profile as active virus: a comparative analysis Open
View article: Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta
Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta Open
The SARS-CoV-2-dependent alteration of the transcriptome of monocyte-derived macrophage (MDM)-infected cells can be linked to the chronological order of the variants' appearance in the human population. Our data suggest an evolution of VOC…
View article: Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale
Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale Open
View article: In situ cryo-electron tomograms #1-#2 of human brain organoid from SOLIST procedure.
In situ cryo-electron tomograms #1-#2 of human brain organoid from SOLIST procedure. Open
View article: Motion-corrected tilt series of native mouse liver using SOLIST procedure. (Minimal dataset for 8.3 Å ribosome)
Motion-corrected tilt series of native mouse liver using SOLIST procedure. (Minimal dataset for 8.3 Å ribosome) Open
View article: In situ cryo-electron tomograms of S. cerevisiae from SOLIST procedure.
In situ cryo-electron tomograms of S. cerevisiae from SOLIST procedure. Open
View article: In situ cryo-electron tomograms #1-#3 of native mouse heart muscle from SOLIST procedure.
In situ cryo-electron tomograms #1-#3 of native mouse heart muscle from SOLIST procedure. Open
View article: In situ cryo-electron tomograms #1-#2 of native mouse corpus callosum from SOLIST procedure.
In situ cryo-electron tomograms #1-#2 of native mouse corpus callosum from SOLIST procedure. Open
View article: Serialized On-grid Lift-In Sectioning for Tomography (SOLIST)
Serialized On-grid Lift-In Sectioning for Tomography (SOLIST) Open
Cryo-focused ion beam milling has enabled groundbreaking structural discoveries in native cells. Progress toward medically relevant applications, however, has been slow. We here present an adaptation of the cryo-lift out procedure for Seri…
View article: Lipid Droplets Define a Sub-Population of Breast Cancer Stem Cells
Lipid Droplets Define a Sub-Population of Breast Cancer Stem Cells Open
Tumor recurrence is now the leading cause of breast cancer-related death. These recurrences are believed to arise from residual cancer stem cells that survive initial therapeutic intervention. Therefore, a comprehensive understanding of ca…