Roberto Badaró
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View article: New Proposed Classification for Psychodermatosis Based on the Complex Interaction Between the Brain and Skin
New Proposed Classification for Psychodermatosis Based on the Complex Interaction Between the Brain and Skin Open
The literature describes several dermatological conditions that are not caused by external agents but result from the complex interaction between the brain and the skin. This interaction gives rise to a variety of dermatological lesions, w…
View article: Transforming the Health Research Workforce in Mozambique: Achievements of the Mozambique Institute for Health Education and Research (MIHER) over a 13‑Year Journey
Transforming the Health Research Workforce in Mozambique: Achievements of the Mozambique Institute for Health Education and Research (MIHER) over a 13‑Year Journey Open
Background: African research capacity is challenged by insufficient infrastructure to solicit and manage grants from local and international funding agencies. Objective: The manuscript provides an overview and discusses lessons learned abo…
View article: Impact of Stressors on The Mental and Physical Health of Professionals Working in Intensive Care Units During The COVID-19 Pandemic
Impact of Stressors on The Mental and Physical Health of Professionals Working in Intensive Care Units During The COVID-19 Pandemic Open
Stress-inducing factors experienced by professionals working in intensive care units (ICUs) during the COVID-19 pandemic have detrimental effects on their mental and physical well-being. The COVID-19 outbreak led to a surge in the number o…
View article: Analysis of COVID-19 diagnostic test implementation in Brazil: strategies in place at the beginning of the pandemic
Analysis of COVID-19 diagnostic test implementation in Brazil: strategies in place at the beginning of the pandemic Open
The World Health Organization considers the mass testing one of the main tools for controlling the COVID-19 pandemic. The aim of this study was to evaluate the strategies adopted by the Brazilian Federal Government to promote population te…
View article: High-Content Imaging-Based Assay for SARS-CoV-2-Neutralizing Antibodies
High-Content Imaging-Based Assay for SARS-CoV-2-Neutralizing Antibodies Open
The COVID-19 pandemic and the consequent emergence of new SARS-CoV-2 variants of concern necessitates the determination of populational serum potency against the virus. Here, we standardized and validated an imaging-based method to quantif…
View article: The Use of Artificial Intelligence (AI) is Customer Service Process in the Pharmaceutical Industry: A Case Study in Public Laboratories
The Use of Artificial Intelligence (AI) is Customer Service Process in the Pharmaceutical Industry: A Case Study in Public Laboratories Open
The Consumer Service (SAC) is an important communication and relationship channel with the customer. This study sought automated data collection and analysis techniques to trace profiles and strategies that are part of the SAC 4.0 model in…
View article: 2773. Brazilian Bacteriophage Activity Against Multidrug-Resistant (MDR) Klebsiella pneumoniae Isolated from Patients with Severe Nosocomial Infection
2773. Brazilian Bacteriophage Activity Against Multidrug-Resistant (MDR) Klebsiella pneumoniae Isolated from Patients with Severe Nosocomial Infection Open
Background Phage therapy has re-emerged as a promising strategy for combatting antimicrobial resistance. Phages are ubiquitous viruses that infect and destroy bacteria and are easily isolated from environmental samples. An impressive reser…
View article: Evaluation of a low-cost trap on capture and possible control of the Aedes aegypti mosquito population
Evaluation of a low-cost trap on capture and possible control of the Aedes aegypti mosquito population Open
The Aedes aegypti mosquito is the primary vector of Zika, Chikungunya and Dengue in Brazil and other parts of the world. Thus, its control is essential, but also a challenge for public health. This study aims to evaluate the performance of…
View article: A randomized clinical trial to evaluate the efficacy of L-carnitine L-tartrate to modulate the effects of SARS-CoV-2 infection
A randomized clinical trial to evaluate the efficacy of L-carnitine L-tartrate to modulate the effects of SARS-CoV-2 infection Open
Introduction L-carnitine (LC) has been associated with inflammatory mediator reduction and with downregulating the angiotensin-converting enzyme-2 (ACE2) receptor, which is the target of SARS-CoV-2 attachment. Methods This pilot phase 2 ra…
View article: An Overview of the Conventional and Novel Methods Employed for SARS-CoV-2 Neutralizing Antibody Measurement
An Overview of the Conventional and Novel Methods Employed for SARS-CoV-2 Neutralizing Antibody Measurement Open
SARS-CoV-2 is the etiological agent of the coronavirus disease-19 (COVID-19) and is responsible for the pandemic that started in 2020. The virus enters the host cell through the interaction of its spike glycoprotein with the angiotensin co…
View article: Current Clinical Landscape and Global Potential of Bacteriophage Therapy
Current Clinical Landscape and Global Potential of Bacteriophage Therapy Open
In response to the global spread of antimicrobial resistance, there is an increased demand for novel and innovative antimicrobials. Bacteriophages have been known for their potential clinical utility in lysing bacteria for almost a century…
View article: Myocardial infarction or myocarditis? A case report and review of a myocardial adverse event associated with mRNA vaccine
Myocardial infarction or myocarditis? A case report and review of a myocardial adverse event associated with mRNA vaccine Open
A 23-year-old man started with chest pain 8 h after his first Pfizer-BioNTech COVID-19 vaccination. ECG evaluation showed sinus tachycardia with ST-segment elevation in D1, AVL, V5, and V6, the findings compatible with acute subepicardial …
View article: An alphavirus-derived replicon polyvalent RNA vaccine induces neutralizing antibodies in mice against omicron SARS-CoV-2 variant of concern
An alphavirus-derived replicon polyvalent RNA vaccine induces neutralizing antibodies in mice against omicron SARS-CoV-2 variant of concern Open
Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fund…
View article: A high content image-based assay for detection and measurement of SARS-CoV-2 neutralizing antibodies
A high content image-based assay for detection and measurement of SARS-CoV-2 neutralizing antibodies Open
Os autores externos submeteram sua publicação para apresentação de trabalho no evento “International Symposium on Immunobiologicals”, que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fund…
View article: Leishmaniasis Vaccines: Applications of RNA Technology and Targeted Clinical Trial Designs
Leishmaniasis Vaccines: Applications of RNA Technology and Targeted Clinical Trial Designs Open
Leishmania parasites cause a variety of discrete clinical diseases that present in regions where their specific sand fly vectors sustain transmission. Clinical and laboratory research indicate the potential of immunization to prevent leish…
View article: Retrospective Cohort Study of COVID-19 in Patients of the Brazilian Public Health System with SARS-CoV-2 Omicron Variant Infection
Retrospective Cohort Study of COVID-19 in Patients of the Brazilian Public Health System with SARS-CoV-2 Omicron Variant Infection Open
Several vaccines against COVID-19 are now available, based on different techniques and made by different laboratories spread around the world. With the roll out of the vaccination process in an advanced stage in many countries, the reduced…
View article: Diagnostic Performance of Three ELISAs for Detection of Antibodies against SARS-CoV-2 in Human Samples
Diagnostic Performance of Three ELISAs for Detection of Antibodies against SARS-CoV-2 in Human Samples Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that causes coronavirus disease 2019 (COVID-19) is a disease with a high rate of transmission. Serological tests are important to perform surveys and to determine the i…
View article: Perception of Professionals from Different Healthcare Units Regarding the Use of Spray Technology for the Instantaneous Decontamination of Personal Protective Equipment during the Coronavirus Disease Pandemic: A Short Analysis
Perception of Professionals from Different Healthcare Units Regarding the Use of Spray Technology for the Instantaneous Decontamination of Personal Protective Equipment during the Coronavirus Disease Pandemic: A Short Analysis Open
Within the context of the coronavirus disease (COVID-19) pandemic, different disinfection technologies have been developed to efficiently exercise microbial control, especially to minimize the potential risks that are associated with trans…
View article: A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia Open
A large number of reports present artificial intelligence (AI) algorithms, which support pneumonia detection caused by COVID-19 from chest CT (computed tomography) scans. Only a few studies provided access to the source code, which limits …
View article: A Brief Analysis of a New Device to Prevent Early Intubation in Hypoxemic Patients: An Observational Study
A Brief Analysis of a New Device to Prevent Early Intubation in Hypoxemic Patients: An Observational Study Open
The need for mechanical ventilation is one of the main concerns related to the care of patients with COVID-19. The aim of this study is to evaluate the efficacy of a bubble device for oxygen supplementation. This device was implemented for…
View article: New Approaches of JBTH
New Approaches of JBTH Open
Due to the increase in the number of articles denied by the JBTH that included in their scope several areas related to engineering and bioengineering, chemistry, and technologies, but not directly linked to the health area, many highly rel…
View article: Retrospective cohort study of COVID-19 in patients of the Brazilian public health system with SARS-COV-2 Omicron variant infection
Retrospective cohort study of COVID-19 in patients of the Brazilian public health system with SARS-COV-2 Omicron variant infection Open
Several vaccines against COVID-19 are now available, based on different techniques and made by different laboratories spread around the world. With the roll out of the vaccination process in an advanced stage in many countries, and the red…
View article: The Importance of Vaccination in the Context of the COVID-19 Pandemic: A Brief Update Regarding the Use of Vaccines
The Importance of Vaccination in the Context of the COVID-19 Pandemic: A Brief Update Regarding the Use of Vaccines Open
The COVID-19 pandemic has led the world to undertake the largest vaccination campaign in human history. In record time, unprecedented scientific and governmental efforts have resulted in the acquisition of immunizers utilizing different te…
View article: Deep Learning Applied to Chest Radiograph Classification—A COVID-19 Pneumonia Experience
Deep Learning Applied to Chest Radiograph Classification—A COVID-19 Pneumonia Experience Open
Due to the recent COVID-19 pandemic, a large number of reports present deep learning algorithms that support the detection of pneumonia caused by COVID-19 in chest radiographs. Few studies have provided the complete source code, limiting t…
View article: Clinical Trials Using Mesenchymal Stem Cells for Spinal Cord Injury: Challenges in Generating Evidence
Clinical Trials Using Mesenchymal Stem Cells for Spinal Cord Injury: Challenges in Generating Evidence Open
Spinal cord injury (SCI) remains an important public health problem which often causes permanent loss of muscle strength, sensation, and function below the site of the injury, generating physical, psychological, and social impacts througho…
View article: The Importance of RNA-Based Vaccines in the Fight against COVID-19: An Overview
The Importance of RNA-Based Vaccines in the Fight against COVID-19: An Overview Open
In recent years, vaccine development using ribonucleic acid (RNA) has become the most promising and studied approach to produce safe and effective new vaccines, not only for prophylaxis but also as a treatment. The use of messenger RNA (mR…
View article: Potential application of novel technology developed for instant decontamination of personal protective equipment before the doffing step
Potential application of novel technology developed for instant decontamination of personal protective equipment before the doffing step Open
The use of personal protective equipment (PPE) has been considered the most effective way to avoid the contamination of healthcare workers by different microorganisms, including SARS-CoV-2. A spray disinfection technology (chamber) was dev…
View article: Numerical and experimental analyses for the improvement of surface instant decontamination technology through biocidal agent dispersion: Potential of application during pandemic
Numerical and experimental analyses for the improvement of surface instant decontamination technology through biocidal agent dispersion: Potential of application during pandemic Open
The transmission of SARS-CoV-2 through contact with contaminated surfaces or objects is an important form of transmissibility. Thus, in this study, we evaluated the performance of a disinfection chamber designed for instantaneous dispersio…
View article: Technological Advancements in Monoclonal Antibodies
Technological Advancements in Monoclonal Antibodies Open
Biopharmaceuticals are innovative solutions that have revolutionized the treatment of important chronic diseases and malignancies. The approval of biosimilar products has become a complex and balanced process, and there are versions of dru…