Roberto Bernabei
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View article: Different Pattern in Circulating MicroRNA‐22‐3p Levels Between Patients With Primary Versus Secondary Sarcopenia
Different Pattern in Circulating MicroRNA‐22‐3p Levels Between Patients With Primary Versus Secondary Sarcopenia Open
Sarcopenia, characterized by decreased skeletal muscle mass and strength, is classified as “primary” (due to aging) or “secondary” (due to diseases). MicroRNA‐22‐3p (miR‐22) regulates muscle differentiation and function. We assessed the di…
View article: Influence of sex and gender-related factors on the knowledge of generic medicines among older patients and caregivers
Influence of sex and gender-related factors on the knowledge of generic medicines among older patients and caregivers Open
Generic medicines (GMs) are bioequivalent to brand-name medicines and more cost-effective, yet their use is limited. Gender-related factors may influence attitudes toward GMs, but data on older adults are scarce. This study aimed to explor…
View article: Knowledge and attitudes towards generic medicines: Point of view of older patients and their caregivers
Knowledge and attitudes towards generic medicines: Point of view of older patients and their caregivers Open
Knowledge about generic drugs remains limited; educational and promotional initiatives are necessary to dispel misconceptions regarding generic drugs.
Influence of Sex and Gender on Knowledge of Generic Medicines Among Older Patients and Caregivers Open
Purpose Generic medicines (GMs) are bioequivalent to brand-name drugs and more cost-effective, yet their use is limited. Gender-related factors may influence attitudes towards GMs, but data on older adults are scarce. This study aimed to e…
View article: Waist-to-calf circumference ratio as a potential indicator of diabetes risk: results from the Longevity Check-Up (Lookup) 8+
Waist-to-calf circumference ratio as a potential indicator of diabetes risk: results from the Longevity Check-Up (Lookup) 8+ Open
Diabetes is a prevalent metabolic condition with substantial health and economic impacts. Therefore, effective and accessible indicators are essential for early detection and prevention. This study investigates the link between the waist-t…
View article: Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy
Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy Open
Infectious diseases pose a significant burden on the general population, particularly older adults who are more susceptible to severe complications. Immunization plays a crucial role in preventing infections and securing a healthier aging,…
View article: Association of Delirium and Depression with Respiratory and Outcome Measures in COVID-19 Inpatients
Association of Delirium and Depression with Respiratory and Outcome Measures in COVID-19 Inpatients Open
Delirium (DEL) and depression (DEP) may impair the course and severity of acute respiratory illness. The impact of such syndromes on respiratory and outcome parameters in inpatients with COVID-19 needs clarification. To clarify the relatio…
Neuropsychological measures of post-COVID-19 cognitive status Open
Background COVID-19 may result in persistent symptoms in the post-acute phase, including cognitive and neurological ones. The aim of this study is to investigate the cognitive and neurological features of patients with a confirmed diagnosi…
View article: Routine immunization of older adults and frail people during the SARS-COV2-pandemic in Italy: a national survey by Italia Longeva
Routine immunization of older adults and frail people during the SARS-COV2-pandemic in Italy: a national survey by Italia Longeva Open
Despite the availability of safe and effective vaccines, older adults and frail people (OAFs) remain far from accomplishing the recommended coverage targets. The SARS-CoV-2 pandemics strongly affected the supply and coverage of routine vac…
View article: Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function
Effects of a 2‐year exercise training on neuromuscular system health in older individuals with low muscle function Open
Background Ageing is accompanied by a progressive loss of skeletal muscle mass and strength, potentially determining the insurgence of sarcopenia. Evidence suggests that motoneuron and neuromuscular junction (NMJ) degeneration contribute t…
A Case of Ralstonia pickettii Bloodstream Infection and the Growing Problem of Healthcare Associated Infections in Frail Older Adults Open
Frailty is a clinically measurable state of vulnerability to developing increased dependency and/or mortality when exposed to a stressor. Chronic diseases, aggressive treatments, antibiotic overuse, microbiota changes, immune senescence, a…
View article: Post-COVID-19 Psychiatric Symptoms in the Elderly: The Role of Gender and Resilience
Post-COVID-19 Psychiatric Symptoms in the Elderly: The Role of Gender and Resilience Open
COVID-19 represents an overwhelming stressor to mental health. Elderly individuals are particularly at risk, but it is still unclear whether the risk is equally distributed among men and women. The aim of this study was to define gender di…
Prolonged emesis as prodromal symptom and exacerbating factor of non-alcoholic Wernicke-Korsakoff Syndrome: a costly diagnostic delay Open
Background.Wernicke-Korsakoff syndrome (WKS) is a serious neurological disorder caused by thiamine (vitamin B1) deficiency.The term refers to two different conditions.Wernicke encephalopathy (WE) is an acute syndrome related to the deficie…
View article: Severe Acquired Brain Injury: Prognostic Factors of Discharge Outcome in Older Adults
Severe Acquired Brain Injury: Prognostic Factors of Discharge Outcome in Older Adults Open
Severe Acquired Brain Injury (sABI) is a leading cause of disability and requires intensive rehabilitation treatment. Discharge from the rehabilitation ward is a key moment in patient management. Delays in patient discharge can adversely a…
Falls among Older Adults: Screening, Identification, Rehabilitation, and Management Open
A fall is an event where a person unintentionally and traumatically finds themselves on the floor or a lower level. Falls are very common, especially in the older adult population. One in four people falls at least once a year after age 65…
Multicomponent intervention to prevent mobility disability in frail older adults: randomised controlled trial (SPRINTT project) Open
Objective To determine whether a multicomponent intervention based on physical activity with technological support and nutritional counselling prevents mobility disability in older adults with physical frailty and sarcopenia. Design Evalua…
Challenges in the Development of Drugs for Sarcopenia and Frailty - Report from the International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force Open
Sarcopenia and frailty represent two burdensome conditions, contributing to a broad spectrum of adverse outcomes. The International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force met virtually in September 2021 to discuss…
Models of hospital care during COVID-19 pandemic in Italy: results from a survey of physicians Open
During COVID-19 pandemic, COVID Hospitals were created throughout Italy and several different models of care for COVID-19 patients were implemented. Methods. We conducted a survey on physicians dedicated to the care of COVID-19 patients wi…
Gait characteristics in community-dwelling older persons with low skeletal muscle mass and low physical performance Open
Background Demographic changes in the western world entail new clinical approaches and challenges in older persons. Low skeletal muscle mass and low physical performance in older persons are both predisposing conditions for disability and …
Developing Pulmonary Rehabilitation for COVID-19: Are We Linked with the Present Literature? A Lexical and Geographical Evaluation Study Based on the Graph Theory Open
The Coronavirus Disease 2019 (COVID-19) pandemic is a severe ongoing global emergency. Despite high rates of asymptomatic patients, in many cases, the infection causes a rapid decline in pulmonary function due to an acute respiratory distr…
Construction and Validation of a Frailty Index in Primary Care in Italy: The Health-Search Frailty Index Open
Recognizing frailty in primary care is important to implement personalized care pathways and for prognostication. The aim of this study was to build and validate a frailty index based on routinely collected primary care data in Italy. We u…