Roberto Chiletti
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View article: Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019–2023) and Melbourne (2016–2022)
Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019–2023) and Melbourne (2016–2022) Open
OBJECTIVES: To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed according t…
View article: Why do children not survive extracorporeal membrane oxygenation?
Why do children not survive extracorporeal membrane oxygenation? Open
Background Extracorporeal membrane oxygenation (ECMO) is used in critically ill children with cardiac and/or respiratory failure. Use is increasing in children with high‐risk comorbidities. Reasons children do not survive ECMO are poorly d…
View article: PB0254 Factor XI and XII in Children Undergoing Extracorporeal Membrane Oxygenation (ECMO)
PB0254 Factor XI and XII in Children Undergoing Extracorporeal Membrane Oxygenation (ECMO) Open
Figure: Serum TPO levels in pediatric patients with ITP. Conclusion(s):The preliminary results suggest that ITP patients presented with differences in serum TPO levels, while serum TPO levels do not appear to play a critical role in differ…
View article: ECMO for Neonatal Sepsis in 2019
ECMO for Neonatal Sepsis in 2019 Open
Sepsis and septic shock in newborns causes mortality and morbidity depending on the organism and primary site. ECMO provides cardiorespiratory support to allow adequate organ perfusion during the time for antibiotics and source control sur…
View article: Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study
Defining benefit threshold for extracorporeal membrane oxygenation in children with sepsis—a binational multicenter cohort study Open
Background The surviving sepsis campaign recommends consideration for extracorporeal membrane oxygenation (ECMO) in refractory septic shock. We aimed to define the benefit threshold of ECMO in pediatric septic shock. Methods Retrospective …
View article: Vancomycin is commonly under‐dosed in critically ill children and neonates
Vancomycin is commonly under‐dosed in critically ill children and neonates Open
Aims Vancomycin is frequently used in critically ill children in whom the drug pharmacokinetics are significantly altered as a result of changes in renal clearance and volume of distribution. Therapeutic drug monitoring (TDM) is recommende…
View article: Ventricular assist device support in patients with single ventricles: the Melbourne experience†
Ventricular assist device support in patients with single ventricles: the Melbourne experience† Open
VAD support in patients with a single ventricle has a high hospital mortality, with 1 of 3 patients surviving to discharge. Systemic VAD support is likely futile in the setting of early Fontan failure or when re-initiation of support is re…