Roberto Contieri
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View article: Penile cancer and lymph node management: a call for standardization
Penile cancer and lymph node management: a call for standardization Open
Purpose This study aims to compare and organize recommendations from the most eminent international guidelines on the staging and treatment of lymph node (LN) involvement in penile cancer (PC). Early recognition and appropriate management …
View article: Refining Active Surveillance Eligibility in Intermediate-risk Non–muscle-invasive Bladder Cancer: The Impact of Time to First Recurrence
Refining Active Surveillance Eligibility in Intermediate-risk Non–muscle-invasive Bladder Cancer: The Impact of Time to First Recurrence Open
View article: The influence of immunocompromised status on recurrence and progression free survival among nonmuscle invasive bladder cancers (NMIBCs) undergoing transurethral resection of bladder tumor (TURBT) and adjuvant intravesical bacillus Calmette Guerin (BCG): Analysis of USA insurance claim data
The influence of immunocompromised status on recurrence and progression free survival among nonmuscle invasive bladder cancers (NMIBCs) undergoing transurethral resection of bladder tumor (TURBT) and adjuvant intravesical bacillus Calmette Guerin (BCG): Analysis of USA insurance claim data Open
BCG immunotherapy is safe in immunocompromised patients. Nevertheless, the efficacy of intravesical BCG in these patients might be suboptimal thus advocating the need for appropriate counselling and a possible lower threshold to consider r…
View article: Radical nephroureterectomy vs kidney sparing surgery for upper tract urothelial carcinoma in solitary kidney patients: a multi-institutional analysis of the ROBUUST 2.0 registry
Radical nephroureterectomy vs kidney sparing surgery for upper tract urothelial carcinoma in solitary kidney patients: a multi-institutional analysis of the ROBUUST 2.0 registry Open
Purpose Radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) in solitary kidney patients is a rare and underreported scenario. This study aims to compare the outcomes of UTUC solitary kidney patients becoming anephr…
View article: Impact of 3D virtual modeling on perioperative outcomes in robot-assisted partial nephrectomy
Impact of 3D virtual modeling on perioperative outcomes in robot-assisted partial nephrectomy Open
View article: Single port robot assisted post-chemotherapy unilateral retroperitoneal lymph node dissection: Feasibility and technical insights
Single port robot assisted post-chemotherapy unilateral retroperitoneal lymph node dissection: Feasibility and technical insights Open
View article: Single-Port Robot-Assisted Post-Chemotherapy Unilateral Retroperitoneal Lymph Node Dissection: Feasibility and Surgical Considerations
Single-Port Robot-Assisted Post-Chemotherapy Unilateral Retroperitoneal Lymph Node Dissection: Feasibility and Surgical Considerations Open
Introduction: Retroperitoneal lymph node dissection (RPLND) is indicated for testicular cancer patients with residual masses post-chemotherapy or stage I-II non-seminomatous germ cell tumors (NSGCT) (1, 2). Open RPLND remains the standard …
View article: Comparative Assessment of Chemotherapy Followed by Consolidative Radical Cystectomy Versus Chemoradiation for Clinically Node-Positive Urothelial Carcinoma of the Bladder
Comparative Assessment of Chemotherapy Followed by Consolidative Radical Cystectomy Versus Chemoradiation for Clinically Node-Positive Urothelial Carcinoma of the Bladder Open
Patients with cN+ bladder cancer who received CRT had a worse prognosis compared to those who underwent chemotherapy followed by RC. The incorporation of more effective systemic therapies is required to improve outcomes, as in our analysis…
View article: Enhanced prognostic value of four‐tier hybrid grading system in Ta non‐muscle‐invasive bladder cancer
Enhanced prognostic value of four‐tier hybrid grading system in Ta non‐muscle‐invasive bladder cancer Open
Objectives To compare the predictive performance of the World Health Organization (WHO) 1973, WHO 2004/2022, the three‐tier (low grade [LG]/Grade 1 [G1]–G2, high grade [HG]/G2, and HG/G3), and four‐tier (LG/G1, LG/G2, HG/G2, and HG/G3) hyb…
View article: Prognostic Impact of Adjuvant Immunotherapy in Patients with High-Risk Upper Tract Urothelial Cancer: Results from the ROBUUST 2.0 Collaborative Group
Prognostic Impact of Adjuvant Immunotherapy in Patients with High-Risk Upper Tract Urothelial Cancer: Results from the ROBUUST 2.0 Collaborative Group Open
Background/Objective: The impact of adjuvant immunotherapy (IO) on the prognosis of patients with upper tract urothelial carcinoma (UTUC) remains unclear. This study examines the association of adjuvant IO with oncologic outcomes in patien…
View article: Machine Learning Driven Diagnostic Pathway for Clinically Significant Prostate Cancer: The Role of Micro-Ultrasound
Machine Learning Driven Diagnostic Pathway for Clinically Significant Prostate Cancer: The Role of Micro-Ultrasound Open
Introduction & Objectives: Detecting clinically significant prostate cancer (csPCa) remains a top priority in delivering high-quality care, yet consensus on an optimal diagnostic pathway is constantly evolving. In this study, we present an…
View article: Rare case of urinary tract infection caused by Cedecea lapagei in a 93-year-old patient in southern Italy
Rare case of urinary tract infection caused by Cedecea lapagei in a 93-year-old patient in southern Italy Open
Cedecea lapagei is a rare Gram-negative bacterium that has been infrequently associated with human infections. It is a non-encapsulated, facultative anaerobic organism that grows well in nonselective laboratory media and exhibits va…
View article: Re: Ben-Max de Ruiter, Jan E. Freund, C. Dilara Savci-Heijink, et al. Prospective Analysis of Confocal Laser Endomicroscopy for Assessment of the Resection Bed for Bladder Tumor. Eur Urol Open Sci 2025;71:57–62
Re: Ben-Max de Ruiter, Jan E. Freund, C. Dilara Savci-Heijink, et al. Prospective Analysis of Confocal Laser Endomicroscopy for Assessment of the Resection Bed for Bladder Tumor. Eur Urol Open Sci 2025;71:57–62 Open
View article: New Insights into Upper Tract Urothelial Carcinoma: Lessons Learned from the ROBUUST Collaborative Study
New Insights into Upper Tract Urothelial Carcinoma: Lessons Learned from the ROBUUST Collaborative Study Open
Upper tract urothelial carcinoma (UTUC) is a rare malignancy, representing only 5–10% of urothelial carcinoma. The mainstay of treatment for high-risk patients is radical nephroureterectomy. Given the aggressive behavior of this disease, a…
View article: Advancing Surgical Management of Penile Cancer: Single Port Bilateral Inguinal Lymph Node Dissection
Advancing Surgical Management of Penile Cancer: Single Port Bilateral Inguinal Lymph Node Dissection Open
Introduction: Penile cancer is a rare but aggressive malignancy, with inguinal lymph node involvement representing a key prognostic indicator (1, 2). NCCN guidelines recommend prophylactic inguinal lymph node dissection (ILND) for intermed…
View article: Feasibility and safety of da Vinci single-port robot-assisted retroperitoneal redo partial nephrectomy
Feasibility and safety of da Vinci single-port robot-assisted retroperitoneal redo partial nephrectomy Open
View article: Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Re-pair in Adults.
Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Re-pair in Adults. Open
Single-stage pedicle preputial tube substitution urethroplasty with corpora cavernosa augmentation using BMG for primary peno-scrotal hypospadias repair in adults is safe and feasable surgery, despite a 30.4% complication rate. This is the…
View article: Biological and therapeutic implications of FGFR alterations in urothelial cancer: A systematic review from non-muscle-invasive to metastatic disease
Biological and therapeutic implications of FGFR alterations in urothelial cancer: A systematic review from non-muscle-invasive to metastatic disease Open
FGFR3 mutations are among the most frequent genomic alterations in urothelial cancer (UC) being mainly associated with the luminal papillary (LumP) subtype. With the establishment of fibroblast growth factor receptor (FGFR) inhibitors, the…
View article: Optimizing Prostate Cancer Diagnostic Work‐Up Through Micro‐Ultrasound: Minimizing Unnecessary Procedures and Reducing Overdiagnoses
Optimizing Prostate Cancer Diagnostic Work‐Up Through Micro‐Ultrasound: Minimizing Unnecessary Procedures and Reducing Overdiagnoses Open
Introduction We aim to critically assess Microultrasound (mUS) clinical performance in an outpatient setting, focusing on its ability to reduce unnecessary diagnostic procedures, potentially reshape prostate cancer (PCa) diagnostic protoco…
View article: The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single‐centre prospective observational cohort study protocol
The Global RAdical Cystectomy Evaluation and Management (GRACEM) pathway: single‐centre prospective observational cohort study protocol Open
Background Despite guideline recommendations, few institutions have implemented clinical pathways that incorporate frailty into routine decision‐making for patients undergoing radical cystectomy (RC). This paper presents an integrated clin…
View article: Xpert Bladder Cancer Detection in Emergency Setting Assessment (XESA Project): A Prospective, Single-centre Trial
Xpert Bladder Cancer Detection in Emergency Setting Assessment (XESA Project): A Prospective, Single-centre Trial Open
Xpert Bladder Cancer Detection is a simple urine test that detects the presence of five genes associated with bladder cancer. We found that for patients visiting the emergency department because of blood in their urine, use of this test co…
View article: Staging Accuracy and Prognostic Value of Prostate-Specific Membrane Antigen PET/CT Strongly Depends on Lymph Node Tumor Burden
Staging Accuracy and Prognostic Value of Prostate-Specific Membrane Antigen PET/CT Strongly Depends on Lymph Node Tumor Burden Open
Objectives: To explore the factors affecting the lymph node metastasis (LNM) detection performance of prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) and to evaluate its prognostic value fo…
View article: Ex Vivo Real-time Assessment of Detrusor Muscle Sampling via Confocal Microscopy During Endoscopic Resection of Bladder Tumor
Ex Vivo Real-time Assessment of Detrusor Muscle Sampling via Confocal Microscopy During Endoscopic Resection of Bladder Tumor Open
View article: Impact of Mayo Adhesive Probability score and BMI on renal functional decline after robotic assisted partial nephrectomy
Impact of Mayo Adhesive Probability score and BMI on renal functional decline after robotic assisted partial nephrectomy Open
Purpose The purpose of this study is to investigate the impact of Mayo Adhesive Probability (MAP) score and body mass index (BMI) on renal function decline after robotic assisted partial nephrectomy (RAPN). Methods We queried our prospecti…
View article: The International Bladder Cancer Group Intermediate-Risk Non-muscle Invasive Bladder Cancer Scoring System Predicts the Need for Intervention for Patients on Active Surveillance
The International Bladder Cancer Group Intermediate-Risk Non-muscle Invasive Bladder Cancer Scoring System Predicts the Need for Intervention for Patients on Active Surveillance Open
View article: Variation in Follow-Up after Radical Cystectomy for Bladder Cancer—An Inventory Roundtable and Literature Review
Variation in Follow-Up after Radical Cystectomy for Bladder Cancer—An Inventory Roundtable and Literature Review Open
Background: Follow-up after radical cystectomy (RC) for bladder cancer can be divided into oncological and functional surveillance. It remains unclear how follow-up after RC should ideally be scheduled. The aim of this report was to gain i…
View article: A Comparative Evaluation of Multiparametric Magnetic Resonance Imaging and Micro-Ultrasound for the Detection of Clinically Significant Prostate Cancer in Patients with Prior Negative Biopsies
A Comparative Evaluation of Multiparametric Magnetic Resonance Imaging and Micro-Ultrasound for the Detection of Clinically Significant Prostate Cancer in Patients with Prior Negative Biopsies Open
Background: The diagnostic process for prostate cancer after a negative biopsy is challenging. This study compares the diagnostic accuracy of micro-ultrasound (mUS) with multiparametric magnetic resonance imaging (mpMRI) for such cases. Me…
View article: Influence of lamina propria invasion extension on T1 high‐grade non‐muscle‐invasive bladder cancer in patients undergoing BCG or radical cystectomy
Influence of lamina propria invasion extension on T1 high‐grade non‐muscle‐invasive bladder cancer in patients undergoing BCG or radical cystectomy Open
Objective To evaluate the prognostic value of T1 substaging in patients treated with bacillus Calmette‐Guérin (BCG) or immediate radical cystectomy (iRC). Materials and Methods We performed an institutional review board‐approved retrospect…
View article: Outcomes and Techniques of Robotic-Assisted Partial Nephrectomy (RAPN) for Renal Hilar Masses: A Comprehensive Systematic Review
Outcomes and Techniques of Robotic-Assisted Partial Nephrectomy (RAPN) for Renal Hilar Masses: A Comprehensive Systematic Review Open
Background: Robot-assisted partial nephrectomy (RAPN) is increasingly being employed in the management of renal cell carcinoma (RCC) and it is expanding in the field of complex renal tumors. The aim of this systematic review was to consoli…
View article: Association of Age with Non–muscle-invasive Bladder Cancer: Unearthing a Biological Basis for Epidemiological Disparities?
Association of Age with Non–muscle-invasive Bladder Cancer: Unearthing a Biological Basis for Epidemiological Disparities? Open