Roberto Mai
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View article: Foraging in conceptual spaces: hippocampal oscillatory dynamics underlying searching for concepts in memory
Foraging in conceptual spaces: hippocampal oscillatory dynamics underlying searching for concepts in memory Open
How does the brain access stored knowledge? It has been proposed that conceptual search engages neurocognitive processes similar to foraging in physical space. We tested this idea using intracranial EEG in patients performing a verbal flue…
View article: High-resolution electrophysiological mapping of effective connectivity of lateral prefrontal cortex
High-resolution electrophysiological mapping of effective connectivity of lateral prefrontal cortex Open
The lateral prefrontal cortex (LPFC) serves as a critical hub for higher-order cognitive and executive functions in the human brain, coordinating brain networks whose disruption has been implicated in many neurological and psychiatric diso…
View article: UM-YOLOv10: Underwater Object Detection Algorithm for Marine Environment Based on YOLOv10 Model
UM-YOLOv10: Underwater Object Detection Algorithm for Marine Environment Based on YOLOv10 Model Open
In order to address the challenges of a low detection accuracy, missed detections, and false detections in marine precious biological target detection within complex marine environments, this paper presents a novel residual attention modul…
View article: Effects of Postoperative Telerehabilitation in Patients with Rotator Cuff Tear: A Systematic Review and Meta-Analysis (Preprint)
Effects of Postoperative Telerehabilitation in Patients with Rotator Cuff Tear: A Systematic Review and Meta-Analysis (Preprint) Open
BACKGROUND Rotator cuff (RC) disorders are the most common cause of shoulder pain, with a prevalence that increases with age. RC tears significantly impact patients' quality of life and pose a substantial economic burden due to high surgi…
View article: Cortical Connectivity Response to Hyperventilation in Focal Epilepsy: A Stereo-EEG Study
Cortical Connectivity Response to Hyperventilation in Focal Epilepsy: A Stereo-EEG Study Open
Hyperventilation (HV) is an activation technique performed during clinical practices to trigger epileptiform activities, supporting the neurophysiological evaluation of patients with epilepsy. Although the role of HV has often been questio…
View article: Desynchronization Index: a New Connectivity Approach for Exploring Epileptogenic Networks
Desynchronization Index: a New Connectivity Approach for Exploring Epileptogenic Networks Open
Objective: This work presents a new computational framework to assist neurophysiologists in Stereoelectroencephalography (SEEG) analysis, with the goal of improving the definition of the Epileptogenic Zone (EZ) in patients with drug-resist…
View article: NLP-based tools for localization of the epileptogenic zone in patients with drug-resistant focal epilepsy
NLP-based tools for localization of the epileptogenic zone in patients with drug-resistant focal epilepsy Open
Epilepsy surgery is an option for people with focal onset drug-resistant (DR) seizures but a delayed or incorrect diagnosis of epileptogenic zone (EZ) location limits its efficacy. Seizure semiological manifestations and their chronologica…
View article: A case of clinical worsening after stereo-electroencephalographic-guided radiofrequency thermocoagulation in a patient with polymicrogyria
A case of clinical worsening after stereo-electroencephalographic-guided radiofrequency thermocoagulation in a patient with polymicrogyria Open
Radiofrequency thermocoagulation (RF-TC) is a wide-used procedure for drug-resistant epilepsy. The technique is considered safe with an overall risk of 1.1% of permanent complications, mainly focal neurological deficits. We report the case…
View article: NLP-based tools for localization of the Epileptogenic Zone in patients with drug-resistant focal epilepsy
NLP-based tools for localization of the Epileptogenic Zone in patients with drug-resistant focal epilepsy Open
Background Drug-resistant focal epilepsy, defined by failure of two antiepileptic drugs, affects about 30% of patients with epilepsy. Epilepsy surgery may represent an alternative options for this population. However, defining the epilepto…
View article: Dataset related to article "IN REPLY FORECASTING SEIZURE FREEDOM AFTER EPILEPSY SURGERY ASSESSING CONCORDANCE BETWEEN NONINVASIVE AND STEREOEEG FINDINGS"
Dataset related to article "IN REPLY FORECASTING SEIZURE FREEDOM AFTER EPILEPSY SURGERY ASSESSING CONCORDANCE BETWEEN NONINVASIVE AND STEREOEEG FINDINGS" Open
.XLS DATASET CONTAINING CLINICAL AND NEUROIMAGING DATA
View article: Dataset related to article "IN REPLY FORECASTING SEIZURE FREEDOM AFTER EPILEPSY SURGERY ASSESSING CONCORDANCE BETWEEN NONINVASIVE AND STEREOEEG FINDINGS"
Dataset related to article "IN REPLY FORECASTING SEIZURE FREEDOM AFTER EPILEPSY SURGERY ASSESSING CONCORDANCE BETWEEN NONINVASIVE AND STEREOEEG FINDINGS" Open
.XLS DATASET CONTAINING CLINICAL AND NEUROIMAGING DATA
View article: Intracerebral electrical stimulations of the temporal lobe: A stereoelectroencephalography study
Intracerebral electrical stimulations of the temporal lobe: A stereoelectroencephalography study Open
The functional anatomy of the anteromesial portion of the temporal lobe and its involvement in epilepsy can be explored by means of intracerebral electrical stimulations. Here, we aimed to expand the knowledge of its physiological and path…
View article: Stereoelectroencephalography: retrospective analysis of 742 procedures in a single centre
Stereoelectroencephalography: retrospective analysis of 742 procedures in a single centre Open
This retrospective description of a surgical series is aimed at reporting on indications, methodology, results on seizures, outcome predictors and complications from a 20-year stereoelectroencephalography (SEEG) activity performed at a sin…
View article: Clinical features of sleep‐related hypermotor epilepsy in relation to the seizure‐onset zone: A review of 135 surgically treated cases
Clinical features of sleep‐related hypermotor epilepsy in relation to the seizure‐onset zone: A review of 135 surgically treated cases Open
Summary Objectives Sleep‐related hypermotor epilepsy ( SHE ), formerly nocturnal frontal lobe epilepsy, is characterized by abrupt and typically sleep‐related seizures with motor patterns of variable complexity and duration. They seizures …
View article: Stereotactic electroencephalography in humans reveals multisensory signal in early visual and auditory cortices
Stereotactic electroencephalography in humans reveals multisensory signal in early visual and auditory cortices Open
Unequivocally demonstrating the presence of multisensory signals at the earliest stages of cortical processing remains challenging in humans. In our study, we relied on the unique spatio-temporal resolution provided by intracranial stereot…
View article: Motor and emotional behaviours elicited by electrical stimulation of the human cingulate cortex
Motor and emotional behaviours elicited by electrical stimulation of the human cingulate cortex Open
The cingulate cortex is a mosaic of different anatomical fields, whose functional characterization is still a matter of debate. In humans, one method that may provide useful insights on the role of the different cingulate regions, and to t…
View article: Seizure duration and latency of hypermotor manifestations distinguish frontal from extrafrontal onset in sleep‐related hypermotor epilepsy
Seizure duration and latency of hypermotor manifestations distinguish frontal from extrafrontal onset in sleep‐related hypermotor epilepsy Open
Summary Sleep‐related hypermotor epilepsy ( SHE ) is an epilepsy syndrome that is characterized by the occurrence of sleep‐related hypermotor seizures of variable complexity and duration. Seizures usually arise in the frontal lobe, but ext…
View article: EPINETLAB: A Software for Seizure-Onset Zone Identification From Intracranial EEG Signal in Epilepsy
EPINETLAB: A Software for Seizure-Onset Zone Identification From Intracranial EEG Signal in Epilepsy Open
The pre-operative workup of patients with drug-resistant epilepsy requires in some candidates the identification from intracranial EEG (iEEG) of the seizure-onset zone (SOZ), defined as the area responsible of the generation of the seizure…
View article: Kurtosis-Based Detection of Intracranial High-Frequency Oscillations for the Identification of the Seizure Onset Zone
Kurtosis-Based Detection of Intracranial High-Frequency Oscillations for the Identification of the Seizure Onset Zone Open
Pathological High-Frequency Oscillations (HFOs) have been recently proposed as potential biomarker of the seizure onset zone (SOZ) and have shown superior accuracy to interictal epileptiform discharges in delineating its anatomical boundar…
View article: Multicenter clinical assessment of improved wearable multimodal convulsive seizure detectors
Multicenter clinical assessment of improved wearable multimodal convulsive seizure detectors Open
Summary Objective New devices are needed for monitoring seizures, especially those associated with sudden unexpected death in epilepsy ( SUDEP ). They must be unobtrusive and automated, and provide false alarm rates (FARs) bearable in ever…
View article: Multi-center clinical assessment of improved wearable multimodal convulsive seizure detectors
Multi-center clinical assessment of improved wearable multimodal convulsive seizure detectors Open
Objective
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\nNew devices are needed for monitoring seizures, especially those associated with sudden unexpected death in epilepsy (SUDEP). They must be unobtrusive and automated, and provide false alarm rates (FARs) bearable in everyday …
View article: Decomposing Tool-Action Observation: A Stereo-EEG Study
Decomposing Tool-Action Observation: A Stereo-EEG Study Open
A description of the spatiotemporal dynamics of human cortical activity during cognitive tasks is a fundamental goal of neuroscience. In the present study, we employed stereo-EEG in order to assess the neural activity during tool-action ob…
View article: Unilobar surgery for symptomatic epileptic spasms
Unilobar surgery for symptomatic epileptic spasms Open
Objective To assess factors associated with favorable seizure outcome after surgery for symptomatic epileptic spasms and improve knowledge on pathophysiology of this seizure type. Methods Inclusion criteria were: (1) age between 6 months a…
View article: Surgical treatment of polymicrogyria‐related epilepsy
Surgical treatment of polymicrogyria‐related epilepsy Open
Summary Objective The role of resective surgery in the treatment of polymicrogyria ( PMG )–related focal epilepsy is uncertain. Our aim was to retrospectively evaluate the seizure outcome in a consecutive series of patients with PMG ‐relat…
View article: Four-dimensional maps of the human somatosensory system
Four-dimensional maps of the human somatosensory system Open
Significance Here, we show how anatomical and functional data recorded from patients undergoing stereo-EEG can be combined to generate highly resolved four-dimensional maps of human cortical processing. We used this technique, which provid…
View article: Reply: The dorsal cingulate cortex as a critical gateway in the network supporting conscious awareness
Reply: The dorsal cingulate cortex as a critical gateway in the network supporting conscious awareness Open
Sir,
We thank Herbet et al. for their interest in our recent article on the results of cortical stimulation of the parietal cortex. In their letter they highlight the importance of the cortical mapping of the medial posterior parietal cor…