Roberto Primi
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View article: Cangrelor in Patients with Percutaneous Coronary Intervention (PCI) After out-of-Hospital Cardiac Arrest (OHCA): A Propensity Score Matchig Analysis
Cangrelor in Patients with Percutaneous Coronary Intervention (PCI) After out-of-Hospital Cardiac Arrest (OHCA): A Propensity Score Matchig Analysis Open
Introduction: Propensity Score Matching (PSM) is used in observational studies to measure the effect of a treatment by removing the bias of confounders, as randomisation is not possible. A multivariable logistic regression is performed to …
View article: Risk Scores Validation: An Example in Cardiology
Risk Scores Validation: An Example in Cardiology Open
Introduction: Clinicians often make important decisions about patient care by estimating the likelihood of a particular disease, condition or event occurring. Prediction models are useful in this context. Development studies aim to develop…
View article: The REVIVE Project: From Survival to Holistic Recovery—A Prospective Multicentric Evaluation of Cognitive, Emotional, and Quality-of-Life Outcomes in Out-of-Hospital Cardiac Arrest Survivors
The REVIVE Project: From Survival to Holistic Recovery—A Prospective Multicentric Evaluation of Cognitive, Emotional, and Quality-of-Life Outcomes in Out-of-Hospital Cardiac Arrest Survivors Open
Background/Objectives: Most survivors of out-of-hospital cardiac arrest (OHCA) may suffer from cognitive, mental difficulties, and fatigue, which negatively impact their quality of life, despite a good physical recovery. However, no defini…
View article: Cangrelor in Patients Undergoing Percutaneous Coronary Intervention After Out-of-Hospital Cardiac Arrest
Cangrelor in Patients Undergoing Percutaneous Coronary Intervention After Out-of-Hospital Cardiac Arrest Open
Background: Cangrelor provides rapid platelet inhibition, making it a potential option for out-of-hospital cardiac arrest (OHCA) survivors undergoing percutaneous coronary intervention (PCI). However, clinical data on its use after OHCA ar…
View article: Out of hospital cardiac arrest outcomes’ determinants: an Italian retrospective cohort study
Out of hospital cardiac arrest outcomes’ determinants: an Italian retrospective cohort study Open
Out-of-hospital cardiac arrest (OHCA) is the most time-critical and time-dependent medical emergency and is associated with low survival rates and poor neurological outcomes at the global level. This study aims at evaluating post-OHCA intr…
View article: Validation of utstein-based score to predict return of spontaneous circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest
Validation of utstein-based score to predict return of spontaneous circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest Open
Funding Acknowledgements None. Background and aims The Utstein Based-ROSC (UB-ROSC) score has been developed to predict ROSC in OHCA victims. Aim of the study was to validate the UB-ROSC score using two Utstein-based OHCA registries: the S…
View article: Perfusion index and mean arterial pressure after return of spontaneous circulation in out-of hospital cardiac arrest (OHCA) and their relationship with perfusion and survival
Perfusion index and mean arterial pressure after return of spontaneous circulation in out-of hospital cardiac arrest (OHCA) and their relationship with perfusion and survival Open
Funding Acknowledgements None. Background Current guidelines for post-cardiac arrest care recommend targeting mean arterial pressure (MAP) to restore adequate perfusion indicated by adequate urine output (UO) and normal or decreasing lacta…
View article: PERIPROCEDURAL ANTITHROMBOTIC THERAPY AND IN–HOSPITAL OUTCOMES IN OUT–OF–HOSPITAL CARDIAC ARREST PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
PERIPROCEDURAL ANTITHROMBOTIC THERAPY AND IN–HOSPITAL OUTCOMES IN OUT–OF–HOSPITAL CARDIAC ARREST PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Open
Background Myocardial Infarction (MI) is the leading cause of Out–of–Hospital Cardiac Arrest (OHCA). The management of periprocedural antithrombotic therapy in this setting is still challenging due to limited data available and given the h…
View article: ROLE OF ST–SEGMENT ELEVATION AT POST–ROSC ECG IN PATIENTS RESUSCITATED FROM OUT–OF–HOSPITAL CARDIAC ARREST
ROLE OF ST–SEGMENT ELEVATION AT POST–ROSC ECG IN PATIENTS RESUSCITATED FROM OUT–OF–HOSPITAL CARDIAC ARREST Open
Background A 12–lead electrocardiogram (ECG), performed after return of spontaneous circulation (ROSC) in out–of–hospital cardiac arrest (OHCA), is essential for the identification of ST–segment elevation). The aim of the study is to inves…
View article: POST–ROSC ECG PREDICTS SURVIVAL AFTER OUT–OF HOSPITAL CARDIAC ARREST. THE PROGRESS SCORE
POST–ROSC ECG PREDICTS SURVIVAL AFTER OUT–OF HOSPITAL CARDIAC ARREST. THE PROGRESS SCORE Open
Background Prognostic assessment of patients following out–of–hospital cardiac arrest (OHCA) is critical to guide care after return of spontaneous circulation (ROSC). The ECG acquired after ROSC in patients with OHCA has proven to be cruci…
View article: COMPLETE VS CULPRIT–LESION–ONLY MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST: INSIGHTS FROM THE MULTICENTRIC LOMBARDIA CARE REGISTRY
COMPLETE VS CULPRIT–LESION–ONLY MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST: INSIGHTS FROM THE MULTICENTRIC LOMBARDIA CARE REGISTRY Open
Background Out–of–hospital Cardiac Arrest (OHCA) is an uncommon yet potentially devastating complication of patients with Myocardial Infarction (MI). Multivessel Disease (MVD) is a frequent occurrence in this setting, being present in near…
View article: Amplitude spectral area of ventricular fibrillation can discriminate survival of patients with out-of-hospital cardiac arrest
Amplitude spectral area of ventricular fibrillation can discriminate survival of patients with out-of-hospital cardiac arrest Open
Background Evidence of the association between AMplitude Spectral Area (AMSA) of ventricular fibrillation and outcome after out-of-hospital cardiac arrest (OHCA) is limited to short-term follow-up. In this study, we assess whether AMSA can…
View article: Electrical storm treatment by percutaneous stellate ganglion block: the STAR study
Electrical storm treatment by percutaneous stellate ganglion block: the STAR study Open
Background and Aims An electrical storm (ES) is a clinical emergency with a paucity of established treatment options. Despite initial encouraging reports about the safety and effectiveness of percutaneous stellate ganglion block (PSGB), ma…
View article: Validation of Utstein-Based score to predict return of spontaneous circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest
Validation of Utstein-Based score to predict return of spontaneous circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest Open
UB-ROSC score represents a reliable tool to predict ROSC probability in OHCA patients. Its application may help the medical decision-making process, providing a realistic stratification of the probability for ROSC.
View article: AMplitude Spectral Area (AMSA) is associated with one-year survival with good neurological outcome in out-of-hospital cardiac arrest
AMplitude Spectral Area (AMSA) is associated with one-year survival with good neurological outcome in out-of-hospital cardiac arrest Open
Background Patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) with shockable rhythms are reported to have better survival rates. Amplitude spectral area (AMSA) of ventricular fibrillation (VF), a surrogate for the metabolic s…
View article: Does the type of mechanical chest compressor affect resuscitation outcome of out of hospital cardiac arrest patients? A propensity-score based comparison of three devices
Does the type of mechanical chest compressor affect resuscitation outcome of out of hospital cardiac arrest patients? A propensity-score based comparison of three devices Open
Background Mechanical cardiopulmonary resuscitation (CPR) devices are currently recommended when high-quality CPR could not be provided and only if used by trained rescuers. Guidelines are against their routinely use since clinical trials …
View article: An innovative MedIcaL dEcision Support tool for neurological ouTcome predictiOn from post-resuscitatioN Electrocardiograms (MILESTONE)
An innovative MedIcaL dEcision Support tool for neurological ouTcome predictiOn from post-resuscitatioN Electrocardiograms (MILESTONE) Open
Background The prediction of poor neurological outcome after Out-of-Hospital Cardiac Arrest (OHCA) represents a major challenge in post-resuscitation care. This is currently based on a complex multiparametric prognostication approach and t…
View article: Validation of Utstein-Based score to predict Return Of Spontaneous Circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest
Validation of Utstein-Based score to predict Return Of Spontaneous Circulation (UB-ROSC) in patients with out-of-hospital cardiac arrest Open
Background Prediction of probability of return of spontaneous circulation (ROSC) during out-of-hospital cardiac arrest (OHCA) is one of the biggest challenge in resuscitation science. The Utstein Based-ROSC (UB-ROSC) score has been develop…
View article: Use of Mechanical Chest Compression for Resuscitation in Out-Of-Hospital Cardiac Arrest—Device Matters: A Propensity-Score-Based Match Analysis
Use of Mechanical Chest Compression for Resuscitation in Out-Of-Hospital Cardiac Arrest—Device Matters: A Propensity-Score-Based Match Analysis Open
Background. Devices for mechanical cardiopulmonary resuscitation (CPR) are recommended when high quality CPR cannot be provided. Different devices are available, but the literature is poor in direct comparison studies. Our aim was to asses…
View article: aMplitude spectral area of ventricular fibrillation and amiOdarone Study in patients with out-of-hospital cArdIaC arrest. The MOSAIC study
aMplitude spectral area of ventricular fibrillation and amiOdarone Study in patients with out-of-hospital cArdIaC arrest. The MOSAIC study Open
Objective Antiarrhythmic drugs are recommended for out of hospital cardiac arrest (OHCA) with shock-refractory ventricular fibrillation (VF). Amplitude Spectral Area (AMSA) of VF is a quantitative waveform measure that describes the amplit…
View article: Association Between Postresuscitation 12‐Lead ECG Features and Early Mortality After Out‐of‐Hospital Cardiac Arrest: A Post Hoc Subanalysis of the PEACE Study
Association Between Postresuscitation 12‐Lead ECG Features and Early Mortality After Out‐of‐Hospital Cardiac Arrest: A Post Hoc Subanalysis of the PEACE Study Open
Background Once the return of spontaneous circulation after out‐of‐hospital cardiac arrest is achieved, a 12‐lead ECG is strongly recommended to identify candidates for urgent coronary angiography. ECG has no apparent role in mortality ris…
View article: C52 GENDER DIFFERENCES IN AMPLITUDE SPECTRAL AREA (AMSA) OF VENTRICULAR FIBRILLATION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST
C52 GENDER DIFFERENCES IN AMPLITUDE SPECTRAL AREA (AMSA) OF VENTRICULAR FIBRILLATION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST Open
Introduction Ventricular fibrillation (VF) Amplitude Spectral Area (AMSA) is a well–established predictor of successful defibrillation and return of spontaneous circulation (ROSC). Attending to the limited evidence on the topic, gender see…
View article: Amplitude of spectral area of ventricular fibrillation as a guide for low energy defibrillation level in patients with out-of-hospital cardiac arrest
Amplitude of spectral area of ventricular fibrillation as a guide for low energy defibrillation level in patients with out-of-hospital cardiac arrest Open
Funding Acknowledgements Type of funding sources: None. Introduction The optimal energy level for shock in biphasic waveform defibrillation represents a significant knowledge gap. Different energy regimens have been trialed; however, a sel…
View article: Vasoactive inotropic score (VIS) at ICU admission predicts neurological outcome and survival in patients resuscitated from an out of hospital cardiac arrest
Vasoactive inotropic score (VIS) at ICU admission predicts neurological outcome and survival in patients resuscitated from an out of hospital cardiac arrest Open
Funding Acknowledgements Type of funding sources: None. Background Since its proposal, Vasoactive Inotropic Score (VIS) was applied in different setting of acute critical care (e.g. pediatric population or post-cardiac surgery). It reflect…
View article: C6 VENTRICULAR FIBRILLATION SPECTRAL AREA (AMSA) AND LOW–ENERGY SHOCK SUCCESS PREDICTION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST
C6 VENTRICULAR FIBRILLATION SPECTRAL AREA (AMSA) AND LOW–ENERGY SHOCK SUCCESS PREDICTION IN PATIENTS WITH OUT–OF–HOSPITAL CARDIAC ARREST Open
Introduction In case of cardiac arrest due to ventricular fibrillation (VF) or pulseless ventricular tachycardia (pVT), the optimal energy level for defibrillation is that which achieves defibrillation and minimize the current–induced myoc…
View article: Mean value of Perfusion Index in patients resuscitated from an out-of-hospital cardiac arrest predict the incidence of lactic acidosis on ICU admission
Mean value of Perfusion Index in patients resuscitated from an out-of-hospital cardiac arrest predict the incidence of lactic acidosis on ICU admission Open
Funding Acknowledgements Type of funding sources: None. Backround Regional and general hypoperfusion cause hypoxia, resulting in excess production of lactate secondary to reduced mitochondrial oxidation. Peripheral perfusion index (PI) is …