Roberto Scacciavillani
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View article: Risk Stratification and Optimal Use of Implantable Cardioverter-Defibrillator Therapy in Primary Prevention of Sudden Cardiac Death in Genetic Cardiomyopathies, with Assessment of the Role of Genetic Variants in Guiding Therapeutic Decisions
Risk Stratification and Optimal Use of Implantable Cardioverter-Defibrillator Therapy in Primary Prevention of Sudden Cardiac Death in Genetic Cardiomyopathies, with Assessment of the Role of Genetic Variants in Guiding Therapeutic Decisions Open
Genetic background is a critical determinant of disease expression, arrhythmic vulnerability, and therapeutic response in inherited cardiomyopathies. Implantable cardioverter-defibrillators (ICD) remain the cornerstone for primary preventi…
View article: Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter
Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter Open
Background: This study aimed to evaluate the effectiveness of right and left atrial strain reservoir (RASr and LASr) in predicting the recurrence of atrial arrhythmias (AAs) following cavotricuspid isthmus ablation (CTIA) for typical atria…
View article: Right atrial strain in atrial fibrillation: the hidden side of the moon
Right atrial strain in atrial fibrillation: the hidden side of the moon Open
Introduction Left atrial (LA) remodeling in atrial fibrillation (AF) is well studied, whereas right atrial (RA) alterations remain poorly characterized. This study evaluates bi-atrial strain dynamics in patients with AF undergoing catheter…
View article: Ventricular substrate characteristics using omnipolar technology-derived vector disarray and peak frequency
Ventricular substrate characteristics using omnipolar technology-derived vector disarray and peak frequency Open
Background Three-dimensional electroanatomic mapping and ablation of ventricular tachycardias (VT) is a complex process that integrates data from multiple procedural steps, including substrate and activation mapping. Purpose To streamline …
View article: Multicenter comparative study of pulsed field ablation vs. radiofrequency balloon ablation for paroxysmal atrial fibrillation: a propensity score matched analysis
Multicenter comparative study of pulsed field ablation vs. radiofrequency balloon ablation for paroxysmal atrial fibrillation: a propensity score matched analysis Open
Introduction Pulsed Field Ablation (PFA) has emerged as a novel, non-thermal energy source to selectively ablate cardiac tissue. We performed a multicentre comparative study on Pulmonary Vein Isolation (PVI) with PFA or Radiofrequency Ball…
View article: Arrhythmic mitral valve Prolapse (MIVAP) Predict Protocol: preliminary results
Arrhythmic mitral valve Prolapse (MIVAP) Predict Protocol: preliminary results Open
Background and Aim Mitral valve prolapse (MVP) is a common valve disease affecting 0.6-3.1% of the general population, occasionally leading to severe complications, including malignant ventricular arrhythmias and sudden cardiac death as th…
View article: Focal lattice tip catheter toggling between pulsed field energy and radiofrequency vs. high power short duration for pulmonary vein isolation: a multicenter study
Focal lattice tip catheter toggling between pulsed field energy and radiofrequency vs. high power short duration for pulmonary vein isolation: a multicenter study Open
Introduction A novel focal 9mm lattice tip catheter, namely Sphere-9 (Affera Inc), has recently received regulatory approval and is part of a technology that allows the delivery of either pulsed electric field or radiofrequency energy and …
View article: Thermal- versus nonthermal-based pulmonary vein isolation in young adults with paroxysmal atrial fibrillation: 1-year results of a multicenter registry
Thermal- versus nonthermal-based pulmonary vein isolation in young adults with paroxysmal atrial fibrillation: 1-year results of a multicenter registry Open
Background Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation. When performed with thermal energy sources (cryoballoon, radiofrequency), PVI leads to collateral damage to major ganglionated plexi (GP); G…
View article: Ultrasound‐Guided Axillary Vein Puncture Versus Landmark‐Guided Approach for Cardiac Implantable Electronic Device Placement
Ultrasound‐Guided Axillary Vein Puncture Versus Landmark‐Guided Approach for Cardiac Implantable Electronic Device Placement Open
Introduction Ultrasound (US)‐guided axillary vein puncture is a safe and effective approach for cardiac implantable electronic device (CIED) implantation, and it is highly recommended by the current consensus document. However, only report…
View article: Noninvasive electrocardiographic imaging assessment of conduction system pacing: A novel algorithm to assess intraventricular synchrony
Noninvasive electrocardiographic imaging assessment of conduction system pacing: A novel algorithm to assess intraventricular synchrony Open
View article: Multielectrode catheter-based pulsed electric field vs. cryoballoon for atrial fibrillation ablation: a systematic review and meta-analysis
Multielectrode catheter-based pulsed electric field vs. cryoballoon for atrial fibrillation ablation: a systematic review and meta-analysis Open
Aims Pulsed field ablation (PFA) is an innovative technology recently adopted for the treatment of atrial fibrillation (AF). Preclinical and clinical studies have reported a remarkable safety profile, as a result of its tissue-specific eff…
View article: Multielectrode catheter-based pulsed field ablation of persistent and long-standing persistent atrial fibrillation
Multielectrode catheter-based pulsed field ablation of persistent and long-standing persistent atrial fibrillation Open
Aims Rhythm control of non-paroxysmal atrial fibrillation (AF) is significantly more challenging, as a result of arrhythmia perpetuation promoting atrial substrate changes and AF maintenance. We describe a tailored ablation strategy target…
View article: Permanent Pacing Reduces Blood Pressure in Older Patients with Drug-resistant Hypertension: A New Pacing Paradigm?
Permanent Pacing Reduces Blood Pressure in Older Patients with Drug-resistant Hypertension: A New Pacing Paradigm? Open
Hypertension (HTN) is a major contributor to cardiovascular mortality. Many patients with drug-resistant hypertension (DRH) also require permanent pacing (PP). This large retrospective study evaluated the effect of PP for conventional PP i…
View article: Shortened radiofrequency delivery time to optimize efficiency and safety of pulmonary vein isolation with the radiofrequency balloon: insights from the COLLABORATE registry
Shortened radiofrequency delivery time to optimize efficiency and safety of pulmonary vein isolation with the radiofrequency balloon: insights from the COLLABORATE registry Open
Aims Previous clinical studies on pulmonary vein isolation (PVI) with a radiofrequency balloon (RFB) reported safe and effective procedures using conventional ablation settings with 20/60 s RF delivery via posterior/anterior (PST/ANT) elec…
View article: Characteristics and Outcome of Patients with or without Previous Implantable Cardioverter Defibrillator Interventions Undergoing Ablation for Ventricular Tachycardia
Characteristics and Outcome of Patients with or without Previous Implantable Cardioverter Defibrillator Interventions Undergoing Ablation for Ventricular Tachycardia Open
Background: Catheter ablation (CA) is a well-established treatment in patients with ventricular tachycardia and appropriate implantable cardioverter defibrillator (ICD) therapies. Methods: We enrolled 57 consecutive carriers of ICD undergo…
View article: Noninvasive electrocardiographic imaging assessment of intraventricular synchrony for conduction system pacing device: a novel algorythm to assess intraventricular synchrony
Noninvasive electrocardiographic imaging assessment of intraventricular synchrony for conduction system pacing device: a novel algorythm to assess intraventricular synchrony Open
Structured Abstract Background Left Bundle branch area pacing has become the procedure of choice for various indications including atrioventricular block and considered to be a physiologic modality of pacing compared to RV apex pacing. Obj…
View article: Remote Monitoring of Cardiac Implantable Electronic Devices in Very Elderly Patients: Advantages and Specific Problems
Remote Monitoring of Cardiac Implantable Electronic Devices in Very Elderly Patients: Advantages and Specific Problems Open
Cardiac implantable electronic devices (CIEDs) offer the benefit of remote monitoring and decision making and find particular applications in special populations such as the elderly. Less transportation, reduced costs, prompt diagnosis, a …
View article: Prognosis of patients undergoing catheter ablation of arrhythmic storm in patients with and without history of previous ICD interventions
Prognosis of patients undergoing catheter ablation of arrhythmic storm in patients with and without history of previous ICD interventions Open
Funding Acknowledgements Type of funding sources: None. Background Catheter ablation (CA) improves prognosis in patients with electrical storm (ES). However, its effectiveness and timing in patients with ventricular tachycardia and appropr…
View article: Clinical Impact of Cardiac Fibrosis on Arrhythmia Recurrence after Ablation in Adults with Congenital Heart Disease
Clinical Impact of Cardiac Fibrosis on Arrhythmia Recurrence after Ablation in Adults with Congenital Heart Disease Open
Background. Adults with congenital heart disease (ACHD) are often affected by cardiac arrhythmias requiring catheter ablation. Catheter ablation in this setting represents the treatment of choice but is flawed by frequent recurrencies. Pre…
View article: A machine-learning based bio-psycho-social model for the prediction of non-obstructive and obstructive coronary artery disease
A machine-learning based bio-psycho-social model for the prediction of non-obstructive and obstructive coronary artery disease Open
View article: Ventricular tachycardia ablation through radiation therapy (VT-ART) consortium: Concept description of an observational multicentric trial via matched pair analysis
Ventricular tachycardia ablation through radiation therapy (VT-ART) consortium: Concept description of an observational multicentric trial via matched pair analysis Open
Introduction Monomorphic ventricular tachycardia (VT) is a life-threatening condition often observed in patients with structural heart disease. Ventricular tachycardia ablation through radiation therapy (VT-ART) for sustained monomorphic v…
View article: Mortality after transvenous lead extraction: A risk prediction model for sustainable care delivery
Mortality after transvenous lead extraction: A risk prediction model for sustainable care delivery Open
Background and Aims Transvenous lead extraction (TLE) has become a pivotal part of a comprehensive lead management strategy, dealing with a continuously increasing demand. Nonetheless, the literature about the long‐term impact of TLE on su…
View article: 626 CARDIOVASCULAR DISEASE PHENOTYPES IN PREGNANCY: GESTATION, PERIPARTUM, AND LONG-TERM OUTCOMES
626 CARDIOVASCULAR DISEASE PHENOTYPES IN PREGNANCY: GESTATION, PERIPARTUM, AND LONG-TERM OUTCOMES Open
Background Maternal cardiovascular physiology is affected by changes that may be impaired in women with cardiovascular disease. Management of these pregnancies is challenging, as prevalence of late childbearing and of women with congenital…
View article: 610 EMERGING TRIGGERS OF ARRHYTHMIC EVENTS IN REMOTE MONITORED PATIENTS
610 EMERGING TRIGGERS OF ARRHYTHMIC EVENTS IN REMOTE MONITORED PATIENTS Open
Background and aims Worldwide, air pollution is the fourth leading cause of death. Both brief and long-term exposures to air pollution have been associated with marked increases in cardiovascular-related morbidity and mortality. Previous s…
View article: Predictors of long-term mortality after transvenous lead extraction of an infected cardiac device: a risk prediction model for sustainable care delivery.
Predictors of long-term mortality after transvenous lead extraction of an infected cardiac device: a risk prediction model for sustainable care delivery. Open
Background and aims : Transvenous lead extraction (TLE) has become a pivotal part of a comprehensive lead management strategy, dealing with a continuously increasing demand. Nonetheless, literature about the long-term impact of TLE on surv…
View article: Short-Term Atrioventricular Dysfunction Recovery after Post-TAVI Pacemaker Implantation
Short-Term Atrioventricular Dysfunction Recovery after Post-TAVI Pacemaker Implantation Open
Permanent pacemaker implantation (PPI) represents a frequent complication after transcatheter aortic valve implantation (TAVI) due to atrio-ventricular (AV) node injury. Predictors of early AV function recovery were investigated. We analyz…
View article: Combining 3-Dimensional Electroanatomic Mapping and Cardiac Magnetic Resonance
Combining 3-Dimensional Electroanatomic Mapping and Cardiac Magnetic Resonance Open
We present the case of a 17-year-old asymptomatic boy with a diagnosis of arrhythmogenic cardiomyopathy. Merging of cardiac magnetic resonance imaging and three-dimensional electroanatomic mapping provided striking visualization of the ass…
View article: Atrioventricular conduction in PM recipients after transcatheter aortic valve implantation: Implications using Wenckebach point measurement
Atrioventricular conduction in PM recipients after transcatheter aortic valve implantation: Implications using Wenckebach point measurement Open
Background Atrioventricular (AV) conduction disturbances requiring permanent pacemaker implantation (PPI) are a common complication after transcatheter aortic valve implantation (TAVI). However, a significant proportion of patients might r…
View article: Successful ventricular tachycardia radioablation in a patient with previous chemical pleurodesis: A case report
Successful ventricular tachycardia radioablation in a patient with previous chemical pleurodesis: A case report Open
Introduction Stereotactic arrhythmia radioablation (STAR) is a novel technique for the ablation of ventricular tachycardia in patients with contraindications to standard procedures, i.e., radiofrequency ablation. Case presentation We repor…
View article: Testosterone-to-estradiol ratio and platelet thromboxane release in ischemic heart disease: the EVA project
Testosterone-to-estradiol ratio and platelet thromboxane release in ischemic heart disease: the EVA project Open