Explanipedia

Topical anaesthesia and decongestion in rhinology Open

Samuel J. M. Hale, R Kim, R. Gordon Douglas · 2023

Medicine

Topical anaesthesia and decongestion of the sinonasal mucosa are used commonly in rhinology practice to facilitate nasal endoscopy, as well as debridement and biopsies. Topical agents used for sinonasal anaesthesia include lignocaine, tetr…

Cross-Strain Neutralizing and Protective Monoclonal Antibodies against EEEV or WEEV Open

Amanda Phelps, Lyn M. O’Brien, David Ulaeto, Frederick W. Holtsberg, Grant C. Liao , et al. · 2021

Biology

The three encephalitic alphaviruses, namely, the Venezuelan, eastern, and western equine encephalitis viruses (VEEV, EEEV, and WEEV), are classified by the Centers for Disease Control and Prevention (CDC) as biothreat agents. Currently, no…

FILIAL PIETY BEYOND THE NUCLEAR FAMILY: A QUALITATIVE ANALYSIS Open

Yuebin Xu, Guanghe Li, Y Zhang, XinQi Dong, Stephanie Bergren , et al. · 2016

Psychology Sociology

abuse screen results (OR: 1.88, 95% CI 1.18-2.98).Being physically hurt (r=0.13,p<.01), insulted (r=0.15,p<.001), threatened (r=0.12,p<.01) and screamed at (r=0.18, p<.001) as a child were significantly correlated with caregiver abuse scre…

EMPOWERING HEALTHCARE TEAMS TO CHAMPION CULTURE CHANGE TO IMPROVE NATIONAL ADULT IMMUNIZATION RATES Open

Yan Xu, Guanghe Li, Y Zhang, XinQi Dong, Stephanie Bergren , et al. · 2016

Business Political science Medicine

abuse screen results (OR: 1.88, 95% CI 1.18-2.98).Being physically hurt (r=0.13,p<.01), insulted (r=0.15,p<.001), threatened (r=0.12,p<.01) and screamed at (r=0.18, p<.001) as a child were significantly correlated with caregiver abuse scre…

ASSOCIATION BETWEEN SOCIODEMOGRAPHIC CHARACTERISTICS AND CAREGIVER BURDEN Open

Yanjun Xu, Guanghe Li, Y Zhang, XinQi Dong, Stephanie Bergren , et al. · 2016

Psychology Medicine

abuse screen results (OR: 1.88, 95% CI 1.18-2.98).Being physically hurt (r=0.13,p<.01), insulted (r=0.15,p<.001), threatened (r=0.12,p<.01) and screamed at (r=0.18, p<.001) as a child were significantly correlated with caregiver abuse scre…

Safety and Immunogenicity of a Parenterally Administered, Structure-Based Rationally Modified Recombinant Staphylococcal Enterotoxin B Protein Vaccine, STEBVax Open

Wilbur H. Chen, Marcela F. Pasetti, Rajan P. Adhikari, Holly Baughman, R. Gordon Douglas , et al. · 2016

Medicine Biology

Staphylococcus aureus produces several enterotoxins and superantigens, exposure to which can elicit profound toxic shock. A recombinant staphylococcal enterotoxin B (rSEB) containing 3 distinct mutations in the major histocompatibility com…

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein Open

Zhen–Yong Keck, Sven Enterlein, Katie A. Howell, Hong Vu, Sergey Shulenin , et al. · 2015

Biology

Filoviruses cause highly lethal viral hemorrhagic fever in humans and nonhuman primates. Current immunotherapeutic options for filoviruses are mostly specific to Ebola virus (EBOV), although other members of Filoviridae such as Sudan virus…

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses Open

Frederick W. Holtsberg, Sergey Shulenin, Hong Vu, Katie A. Howell, Sonal Patel , et al. · 2015

Biology

The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses. Monoclonal antibody (MAb) cocktails have shown great potential as EVD therapeutics; howe…

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