Ryan M. Richards
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View article: Identification of novel, potent, and selective JAK2V617F inhibitors
Identification of novel, potent, and selective JAK2V617F inhibitors Open
The predominant oncogenic variant driving myeloproliferative neoplasms (MPNs) is the JAK2V617F substitution, where valine is replaced by phenylalanine in Janus kinase 2 (JAK2). Approximately 95% of polycythemia vera (PV) patients, and in o…
View article: Machine learning informed rational design of high entropy double perovskite oxide universal air/steam electrodes for solid oxide electrochemical cells
Machine learning informed rational design of high entropy double perovskite oxide universal air/steam electrodes for solid oxide electrochemical cells Open
View article: Influence of Co and Mn Doping on the Surface Reconstruction of Faceted NiO(111) Nanosheets after the Oxygen Evolution Reaction
Influence of Co and Mn Doping on the Surface Reconstruction of Faceted NiO(111) Nanosheets after the Oxygen Evolution Reaction Open
Understanding dynamic surface reconstruction processes on transition metal oxides for the oxygen evolution reaction (OER) in alkaline electrolytes is crucial to the development of more active catalysts in water electrolysis technologies. E…
View article: Defining preclinical efficacy with the DNAPK inhibitor AZD7648 in combination with olaparib: a minimal systems pharmacokinetic–pharmacodynamic model
Defining preclinical efficacy with the DNAPK inhibitor AZD7648 in combination with olaparib: a minimal systems pharmacokinetic–pharmacodynamic model Open
View article: Collaborative Learning in Virtual Computer Laboratory Exercises
Collaborative Learning in Virtual Computer Laboratory Exercises Open
View article: Molten salt synthesis of increased (100)-facet and polycrystalline nickel oxide nanoparticles for the oxygen evolution reaction: impact of facet and crystallinity on electrocatalysis
Molten salt synthesis of increased (100)-facet and polycrystalline nickel oxide nanoparticles for the oxygen evolution reaction: impact of facet and crystallinity on electrocatalysis Open
Nickel oxide nanocubes with increased (100) surface facet presence (NiO(100)) were synthesized through a molten salt synthesis procedure in order to investigate the relationship between the surface facet and OER performance.
View article: The first year of <i>RSC Applied Interfaces</i>: a retrospective
The first year of <i>RSC Applied Interfaces</i>: a retrospective Open
Shelley A. Claridge, Jianbin Huang, Serena Margadonna, Ryan Richards and Federico Rosei share their retrospective in an editorial celebrating the first year of publication of RSC Applied Interfaces .
View article: Bifunctionality of supported metal hydrodeoxygenation catalysts
Bifunctionality of supported metal hydrodeoxygenation catalysts Open
The transition to sustainable energy relies on innovative methods to convert biomass-derived compounds into viable biofuels.
View article: Supercritical preparation of doped (111) facetted nickel oxide for the oxygen evolution reaction
Supercritical preparation of doped (111) facetted nickel oxide for the oxygen evolution reaction Open
Herein a unique NiO(111) nanosheet pre-catalyst has been doped with Fe, Mn, or Co to reduce its OER overpotential. Dopant inclusion resulted in changes to the NiO bulk and surface properties which resulted in varying activities towards the…
View article: Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors
Synthetic chemistry enabling the discovery and development of a series of pyrazoles as HPK1 inhibitors Open
Late-stage pyrazole functionalization was used to rapidly explore SAR and led to the identification of a potent HPK1 inhibitor.
View article: Can Hume-Rothery rules predict single-phase high-entropy rocksalt oxide phases?
Can Hume-Rothery rules predict single-phase high-entropy rocksalt oxide phases? Open
In the quest for understanding and tailoring the formation and properties of entropically stabilised ceramics, rocksalt-structured (MgNiCoCuZn)O occupies a central place. To date, most of the reported high-entropy rocksalt oxides (HERSOs) …
View article: Influence of Annealing Temperature on the OER Activity of NiO(111) Nanosheets Prepared via Microwave and Solvothermal Synthesis Approaches
Influence of Annealing Temperature on the OER Activity of NiO(111) Nanosheets Prepared via Microwave and Solvothermal Synthesis Approaches Open
Earth-abundant transition metal oxides are promising alternatives to precious metal oxides as electrocatalysts for the oxygen evolution reaction (OER) and are intensively investigated for alkaline water electrolysis. OER electrocatalysis, …
View article: Mining electronics waste: Experimental and computational mechanistic insights into organic aqua regia as an extraction method
Mining electronics waste: Experimental and computational mechanistic insights into organic aqua regia as an extraction method Open
In the previous decade, organic aqua regia (OAR) was discovered as a mixture of pyridine and thionyl chloride that has been observed to surprisingly yet notably selectively dissolve precious metals, dissolution‐resistant gold. Given the no…
View article: Catalysis at the intersection of sustainable chemistry and a circular economy
Catalysis at the intersection of sustainable chemistry and a circular economy Open
View article: Targeted synthesis, characterization, and electrochemical analysis of transition-metal-oxide catalysts for the oxygen evolution reaction
Targeted synthesis, characterization, and electrochemical analysis of transition-metal-oxide catalysts for the oxygen evolution reaction Open
View article: Light-driven interfaces for PFAS detection and destruction
Light-driven interfaces for PFAS detection and destruction Open
Due to exposure risks and health concerns, global limitations on per- and polyfluoroalkyl substances (PFAS) have become increasingly restrictive. Light-driven technologies can potentially destroy and detect PFAS, addressing these limitatio…
View article: Editorial: Small‐Structure Innovation of Catalysis Powers a Sustainable Future
Editorial: Small‐Structure Innovation of Catalysis Powers a Sustainable Future Open
To tackle the grand twin challenges of sustainable energy supply and climate change, Small Structures of the advanced catalysts can play a central role in not only promoting the energy conversion such as green hydrogen production and energ…
View article: Supplementary Figure 5 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 5 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure validates the tumor data in a second mouse experiment.
View article: Supplementary Figure 4 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 4 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure reports additional RPPA data.
View article: Supplementary Figure 2 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 2 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure validates the tumor growth data with another autophagy gene.
View article: Supplementary Table 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Table 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Table lists primers used for RQ-PCR.
View article: Supplementary Figure 3 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 3 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure show alternative analysis for cell death in the tumors.
View article: Supplementary Figure 2 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 2 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure validates the tumor growth data with another autophagy gene.
View article: Supplementary Figure 4 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 4 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure reports additional RPPA data.
View article: Data from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Data from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
Beclin 1 has nonautophagic functions that include its ability to regulate endocytic receptor trafficking. However, the contribution of this function to tumor suppression is poorly understood. Here, we provide in vivo evidence that B…
View article: Supplementary Figure 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure validates Beclin 1 regulation of HRS phosphorylation.
View article: Supplementary Figure 6 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 6 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure show analysis of shATG5 tumors.
View article: Supplementary Figure 3 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 3 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure show alternative analysis for cell death in the tumors.
View article: Supplementary Figure 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure 1 from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
This Figure validates Beclin 1 regulation of HRS phosphorylation.
View article: Supplementary Figure legends from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation
Supplementary Figure legends from Beclin 1 Promotes Endosome Recruitment of Hepatocyte Growth Factor Tyrosine Kinase Substrate to Suppress Tumor Proliferation Open
Supplementary Figure legends