Explanipedia

Pregnancy after kidney and liver transplantation Open

Amy Wise, Nina Diana, B Bobat, Robin Saggers, Shastra Bhoora , et al. · 2024

Pregnancy in kidney and liver transplant recipients presents unique challenges and risks for both maternal and fetal health. This article examines the management of pregnancy in kidney and liver transplant recipients, focusing on pre-pregn…

Impact of COVID-19 Lockdowns on Rates of Adolescent Pregnancies: A Systematic Review Open

Lauren Hookham, Jackeline Alger, Margit Endler, Michael Enwere, Deborah Eskenazi , et al. · 2024

Background: Education is known to protect adolescent girls from unplanned pregnancy. School closures were component of COVID-19 “lockdown measures”. The impact of these measures on adolescent pregnancy worldwideis unknown. Methods: We perf…

Impact of COVID-19 Lockdowns on Rates of Adolescent Pregnancies: A Systematic Review Open

Laurens Hookham, Jackeline Alger, Margit Endler, Michael Enwere, Deborah Eskenazi , et al. · 2024

Challenges Facing PICUs in Low- and Middle-Income Countries in the Treatment of Emerging Multidrug-Resistant Organisms: a Review and Perspective from a South African PICU Open

Robin Saggers, Lesego M. Mothibi, Adam Irwin, Kuban D. Naidoo · 2023

Purpose of Review Antimicrobial resistance continues to increase throughout the world, with the impact on critically ill children in low- and middle-income paediatric intensive care units largely unknown. Recent Findings There has been a g…

Implementation and maintenance of a voluntary data contribution system to an international network: The Vermont Oxford Network at Charlotte Maxeke Johannesburg Academic Hospital Open

Rossella Bandini, Tanusha Ramdin, Robin Saggers, Daynia Ballot · 2023

Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoOBS) Open

Neal Russell, Wolfgang Stöhr, Nishad Plakkal, Aislinn Cook, James A. Berkley , et al. · 2023

Background There is limited data on antibiotic treatment in hospitalized neonates in low- and middle-income countries (LMICs). We aimed to describe patterns of antibiotic use, pathogens, and clinical outcomes, and to develop a severity sco…

Epidemiology, risk factors and outcomes associated with candidaemia in very low birth weight infants at a tertiary South African Hospital over a 7-year period (2013–2019) Open

Tanusha Ramdin, Vindana Chibabhai, Robin Saggers, Rossella M. Bandini, Daynia Ballot · 2023

Introduction: Candidaemia is a significant problem in neonatal units and is associated with high morbidity, including long-term neurodevelopmental impairment in survivors, and high mortality of very low birth weight infants (VLBWI). Method…

Myositis ossificans in a child athlete: a case study Open

Romy Sapire, Radina Nenova, Perusha Gounder, Alka Rampersad, Vhonani Maboho , et al. · 2022

Background: A 13-year-old female athlete presented with a painful lesion in her right buttock for which she had been receiving physiotherapy. It was keeping her from participating in sports. Aim: To report on a case of traumatic myositis o…

Association between regular physical activity and the protective effect of vaccination against SARS-CoV-2 in a South African case–control study Open

Shirley Collie, Robin Saggers, Rossella M. Bandini, Lizelle Steenkamp, Jared Champion , et al. · 2022

Background Both vaccination and physical activity have been shown to independently decrease the likelihood of severe COVID-19 infection. Objective To assess the association between regular physical activity and vaccination against COVID-19…

Factors influencing survival and short-term outcomes of very low birth weight infants in a tertiary hospital in Johannesburg Open

Kristin Ingemyr, Anders Elfvin, Elisabet Hentz, Robin Saggers, Daynia Ballot · 2022

Background The neonatal mortality rate in South Africa is lower than the global average, but still approximately five times higher than some European and Scandinavian countries. Prematurity, and its complications, is the main cause (35%) o…

The NeoSep Severity and Recovery scores to predict mortality in hospitalized neonates and young infants with sepsis derived from the global NeoOBS observational cohort study Open

Neal Russell, Wolfgang Stöhr, Aislinn Cook, James A. Berkley, B. Adhisivam , et al. · 2022

Background Sepsis severity scores are used in clinical practice and trials to define risk groups. There are limited data to derive hospital-based sepsis severity scores for neonates and young infants in high-burden low- and middle-income c…

Neurodevelopmental Outcomes of Extremely Low Birth Weight Survivors in Johannesburg, South Africa Open

Tanusha Ramdin, Robin Saggers, Rossella M. Bandini, Yoliswa Magadla, Aripfani V. Mphaphuli , et al. · 2022

Background: Improved survival in extremely low birth weight infants (ELBWI) in Sub-Saharan Africa has raised the question whether these survivors have an increased chance of adverse neurodevelopmental outcomes. Objectives To describe neuro…

A Pandemic We Continue to Ignore: South Africa’s Disease Burden of Physical Inactivity Open

Jon Patricios, Robin Saggers, Georgia Torres · 2022

The benefits of regular physical activity (PA) in mitigating the effects of non-communicable diseases have been well described. More recently, highlighted by a global need to protect large populations against the COVID-19 pandemic, the imm…

Small steps, strong shield: directly measured, moderate physical activity in 65 361 adults is associated with significant protective effects from severe COVID-19 outcomes Open

Lizelle Steenkamp, Robin Saggers, Rossella M. Bandini, Saverio Stranges, Yun‐Hee Choi , et al. · 2022

Objective To determine the association between directly measured physical activity and hospitalisation, intensive care unit (ICU) admission, ventilation and mortality rates in patients with a confirmed diagnosis of COVID-19. Methods Direct…

Sirenomelia with major cardiac anomalies Open

Robin Saggers, Charlton Rw, Phumza Nongena, Sithembiso Velaphi · 2021

Sirenomelia is a rare and serious congenital anomaly characterised by fusion of the lower limbs, usually a single umbilical artery and malformations of the genitourinary and gastrointestinal tracts. In this report, we present clinical and …

Recommendations for the return of spectators to sport stadiums: A South African Sports Medicine Association (SASMA) position statement – Part 4 Open

Lervasen Pillay, Jon Patricios, Dina C. Janse van Rensburg, Robin Saggers, Dimakatso Ramagole , et al. · 2021

All sports were discontinued in 2020 with the arrival of COVID-19. Since then most have been reinstated, albeit without spectators. However, several countries have put together a number of different risk-mitigating strategies to allow spec…

Recommendations for athletes and COVID-19 vaccinations: A South African Sports Medicine Association (SASMA) position statement – Part 3 Open

Lervasen Pillay, Jon Patricios, Dina C. Janse van Rensburg, Robin Saggers, Dimakatso Ramagole , et al. · 2021

The COVID-19 pandemic initially led to the shutdown of all sport at a high cost to both the economy and athlete health. As risk-mitigating protocols evolved and were implemented, the playing of sport returned slowly to normal. The introduc…

The effects of exposure to HIV in neonates at a referral hospital in South Africa Open

Helena Mellqvist, Robin Saggers, Anders Elfvin, Elisabet Hentz, Daynia Ballot · 2021

Global research priorities for COVID-19 in maternal, reproductive and child health: Results of an international survey Open

Melanie Etti, Jackeline Alger, Sofía P. Salas, Robin Saggers, Tanusha Ramdin , et al. · 2021

Background The World Health Organization’s “ Coordinated Global Research Roadmap : 2019 Novel Coronavirus ” outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the …

Global research priorities for COVID-19 in maternal, reproductive and child health: results of an international survey Open

Melanie Etti, Jackeline Alger, Sofía P. Salas, Robin Saggers, Tanusha Ramdin , et al. · 2021

Background The World Health Organization’s “ Coordinated Global Research Roadmap: 2019 Novel Coronavirus ” outlined the need for research that focuses on the impact of COVID-19 on pregnant women and children. More than one year after the f…

Considerations for COVID-19 vaccination in pregnancy. Open

Jarrod Zamparini, Lyle Murray, Robin Saggers, Amy Wise, Hennie Lombaard · 2021

Pregnant women are at greater risk of severe COVID-19 than non-pregnant women. Despite limited safety data on use of COVID-19 vaccines in pregnancy, many international societies have recommended their use when pregnant women are at particu…

Working out: lockdown's lessons to increase physical activity Open

Jon Patricios, Robin Saggers, Zaid Saeed, Mosima Mabunda, Deepak S. Patel · 2021

COVID-19 and Multisystem Inflammatory Syndrome in Children Open

Robin Saggers · 2021

Setting : A literature review was undertaken to provide an overview of the evidence of COVID-19 in the paediatric population with special interest in the South African situation. Key Messages : Children of all ages are susceptible to COVID…

Neurodevelopmental outcome in extremely low birth weight infants in Johannesburg, South Africa Open

Tanusha Ramdin, Yoliswa Magadla, Robin Saggers, Aripfani Veronica Mphaphuli, Rossella M. Bandini , et al. · 2020

Background: Improved survival in preterm infants whether due to technological progress or treatment like antenatal steroids, surfactant administration or nasal continuous positive airway pressure (NCPAP) and aggressive resuscitation have r…

‘Make exercise the elixir across an economic divide’: A message to COVID-19 decision makers Open

Jon Patricios, Robin Saggers, Jarrad Van Zuydam, Brad Gelbart · 2020

South Africa, like other countries around the world, has used a lockdown strategy to address the initial phases of the COVID- 19 epidemic. The significant restrictions on population movement have included initially limiting exercis…

COVID-19 Preparedness in a Neonatal Unit at a Tertiary Hospital in Johannesburg, South Africa Open

Robin Saggers, Tanusha Ramdin, Rossella M. Bandini, Daynia Ballot · 2020

Background: The novel coronavirus disease 2019 (COVID-19) pandemic has spread to South Africa and poses an infection risk in pregnant women and their newborns, as well as health-care workers and other patients. Objective: To discuss the im…

Robin Saggers YOU? Author Swipe