Robin Wijsman
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Author Swipe
View article: “AI tumor delineation for all breathing phases in early-stage NSCLC”
“AI tumor delineation for all breathing phases in early-stage NSCLC” Open
The Swin + Dyn Net algorithm, trained on the maximum expiration CT-scan effectively delineated gross tumor volumes in all breathing phases and the resulting ITV showed a good agreement with the ground truth (surface DSC = 0.79 ± 0.16 using…
View article: Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation
Association between dose to cardiac structures and overall survival: A multivariable analysis in a large, multi-institutional database of stage III NSCLC patients with external validation Open
View article: Recovery of quality of life in 574 patients with inoperable lung cancer undergoing (chemo)radiotherapy
Recovery of quality of life in 574 patients with inoperable lung cancer undergoing (chemo)radiotherapy Open
Patients experienced a temporary increase in complaints after finishing (chemo)radiotherapy, QoL returned to baseline level and remained stable up to five years of follow-up.
View article: Rising incidence of radiation pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiotherapy
Rising incidence of radiation pneumonitis after adjuvant durvalumab in NSCLC patients treated with concurrent chemoradiotherapy Open
Background and purpose: Adding adjuvant durvalumab to chemoradiotherapy (CRT) improves overall survival (OS) rates in locally advanced Non-Small-Cell Lung Cancer (NSCLC). However, recent data suggests that this new modality increases the i…
View article: Robustness Evaluation in proton therapy: An ESTRO Delphi consensus
Robustness Evaluation in proton therapy: An ESTRO Delphi consensus Open
View article: Real-World Acute Toxicity and 90-Day Mortality in Patients With Stage I NSCLC Treated With Stereotactic Body Radiotherapy
Real-World Acute Toxicity and 90-Day Mortality in Patients With Stage I NSCLC Treated With Stereotactic Body Radiotherapy Open
View article: Baseline Blood CD8+ T Cell Activation Potency Discriminates Responders from Non-Responders to Immune Checkpoint Inhibition Combined with Stereotactic Radiotherapy in Non-Small-Cell Lung Cancer
Baseline Blood CD8+ T Cell Activation Potency Discriminates Responders from Non-Responders to Immune Checkpoint Inhibition Combined with Stereotactic Radiotherapy in Non-Small-Cell Lung Cancer Open
Background: Tumor-infiltrating immune cells have been correlated with prognosis for patients treated with immune checkpoint inhibitor (ICI) treatment of various cancers. However, no robust biomarker has been described to predict treatment …
View article: A planning study of proton therapy dose escalation for non-small cell lung cancer
A planning study of proton therapy dose escalation for non-small cell lung cancer Open
View article: FIRST EXPERIENCE WITH IN VIVO RANGE PROBING QUALITY CONTROL PROCEDURE FOR MOVING TARGETS TREATED WITH INTENSITY-MODULATED PROTON THERAPY
FIRST EXPERIENCE WITH IN VIVO RANGE PROBING QUALITY CONTROL PROCEDURE FOR MOVING TARGETS TREATED WITH INTENSITY-MODULATED PROTON THERAPY Open
View article: Probability maps for deep learning-based head and neck tumor segmentation: Graphical User Interface design and test
Probability maps for deep learning-based head and neck tumor segmentation: Graphical User Interface design and test Open
This study shows that DL-generated tumor probability maps are explainable, transparent, intuitive and a better alternative to the single output of tumor segmentation models.
View article: Continuous and bilevel positive airway pressure may improve radiotherapy delivery in patients with intra-thoracic tumors
Continuous and bilevel positive airway pressure may improve radiotherapy delivery in patients with intra-thoracic tumors Open
View article: Association between Dose to Cardiac Structures and Overall Survival: a Multivariable Analysis in a Large, Multi-Institutional Database of Stage III NSCLC Patients with External Validation
Association between Dose to Cardiac Structures and Overall Survival: a Multivariable Analysis in a Large, Multi-Institutional Database of Stage III NSCLC Patients with External Validation Open
View article: Estimating how contouring differences affect normal tissue complication probability modelling
Estimating how contouring differences affect normal tissue complication probability modelling Open
Our methodology can be used to estimate whether a given contouring model is fit for NTCP model development. For the heart in comparable datasets, average Dice should be at least as high as between our manual and deep learning contours for …
View article: Proton and photon radiotherapy in stage III NSCLC: Effects on hematological toxicity and adjuvant immune therapy
Proton and photon radiotherapy in stage III NSCLC: Effects on hematological toxicity and adjuvant immune therapy Open
View article: External validation of NTCP-models for radiation pneumonitis in lung cancer patients treated with chemoradiotherapy
External validation of NTCP-models for radiation pneumonitis in lung cancer patients treated with chemoradiotherapy Open
View article: Adjuvant durvalumab after concurrent chemoradiotherapy for patients with unresectable stage III NSCLC harbouring uncommon genomic alterations
Adjuvant durvalumab after concurrent chemoradiotherapy for patients with unresectable stage III NSCLC harbouring uncommon genomic alterations Open
View article: Clinical 3D/4D cumulative proton dose assessment methods for thoracic tumours with large motion
Clinical 3D/4D cumulative proton dose assessment methods for thoracic tumours with large motion Open
View article: Safety and tolerability of stereotactic radiotherapy combined with durvalumab with or without tremelimumab in advanced non-small cell lung cancer, the phase I SICI trial
Safety and tolerability of stereotactic radiotherapy combined with durvalumab with or without tremelimumab in advanced non-small cell lung cancer, the phase I SICI trial Open
The combination of SBRT to the primary tumor and double immunotherapy in advanced NSCLC patients is safe and feasible.
View article: Inter- and intrafractional 4D dose accumulation for evaluating ΔNTCP robustness in lung cancer
Inter- and intrafractional 4D dose accumulation for evaluating ΔNTCP robustness in lung cancer Open
View article: Survival prediction for stage I-IIIA non-small cell lung cancer using deep learning
Survival prediction for stage I-IIIA non-small cell lung cancer using deep learning Open
Multivariable analysis showed that age and clinical stage were significant prognostic clinical factors for 2-year OS. Using these two clinical variables in combination with image features from pre-treatment CT scans, the hybrid model achie…
View article: The Dutch Lung Cancer Audit-Radiotherapy (DLCA-R): Real-World Data on Stage III Non-Small Cell Lung Cancer Patients Treated With Curative Chemoradiation
The Dutch Lung Cancer Audit-Radiotherapy (DLCA-R): Real-World Data on Stage III Non-Small Cell Lung Cancer Patients Treated With Curative Chemoradiation Open
View article: Deep learning–based 4D‐synthetic CTs from sparse‐view CBCTs for dose calculations in adaptive proton therapy
Deep learning–based 4D‐synthetic CTs from sparse‐view CBCTs for dose calculations in adaptive proton therapy Open
Background Time‐resolved 4D cone beam–computed tomography (4D‐CBCT) allows a daily assessment of patient anatomy and respiratory motion. However, 4D‐CBCTs suffer from imaging artifacts that affect the CT number accuracy and prevent accurat…
View article: Corrigendum to “Trends and variations in the treatment of stage I-III small cell lung cancer from 2008 to 2019: A nationwide population-based study from the Netherlands” [Lung Cancer 162C (2021) 61–70]
Corrigendum to “Trends and variations in the treatment of stage I-III small cell lung cancer from 2008 to 2019: A nationwide population-based study from the Netherlands” [Lung Cancer 162C (2021) 61–70] Open
View article: Clinical suitability of deep learning based synthetic CTs for adaptive proton therapy of lung cancer
Clinical suitability of deep learning based synthetic CTs for adaptive proton therapy of lung cancer Open
Purpose Adaptive proton therapy (APT) of lung cancer patients requires frequent volumetric imaging of diagnostic quality. Cone‐beam CT (CBCT) can provide these daily images, but x‐ray scattering limits CBCT‐image quality and hampers dose c…
View article: Trends and variations in the treatment of stage I-III small cell lung cancer from 2008 to 2019: A nationwide population-based study from the Netherlands
Trends and variations in the treatment of stage I-III small cell lung cancer from 2008 to 2019: A nationwide population-based study from the Netherlands Open
Objectives: Recent treatment patterns for small cell lung cancer (SCLC) in the Netherlands were unknown. This nationwide population-based study describes trends and variations in the treatment of stage I-III SCLC in the Netherlands over th…
View article: Deep learning model for automatic contouring of cardiovascular substructures on radiotherapy planning CT images: Dosimetric validation and reader study based clinical acceptability testing
Deep learning model for automatic contouring of cardiovascular substructures on radiotherapy planning CT images: Dosimetric validation and reader study based clinical acceptability testing Open
This model can be used to contour the heart, cardiac chambers, and great vessels in large datasets of RT planning thoracic CT images accurately, quickly, and consistently. Additionally, the model can be used as a time-saving tool for conto…
View article: P21.03 Dutch Lung Cancer Audit-Radiotherapy: Real-World Data on Stage III Non-Small Cell Lung Cancer Treated With Radiotherapy Only
P21.03 Dutch Lung Cancer Audit-Radiotherapy: Real-World Data on Stage III Non-Small Cell Lung Cancer Treated With Radiotherapy Only Open
View article: Towards the clinical implementation of intensity-modulated proton therapy for thoracic indications with moderate motion: Robust optimised plan evaluation by means of patient and machine specific information
Towards the clinical implementation of intensity-modulated proton therapy for thoracic indications with moderate motion: Robust optimised plan evaluation by means of patient and machine specific information Open
View article: Pericardial effusion after radiotherapy for Non-Small Cell Lung Cancer
Pericardial effusion after radiotherapy for Non-Small Cell Lung Cancer Open
View article: Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours
Evaluation of continuous beam rescanning versus pulsed beam in pencil beam scanned proton therapy for lung tumours Open
The treatment of moving targets with pencil beam scanned proton therapy (PBS-PT) may rely on rescanning strategies to smooth out motion induced dosimetric disturbances. PBS-PT machines, such as Proteus®Plus (PPlus) and Proteus®One (POne), …