Robyn Sysko
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View article: Altered Brain Network Topology during Successful Response Inhibition in Children with Binge Eating
Altered Brain Network Topology during Successful Response Inhibition in Children with Binge Eating Open
Aim Although a risk factor for the later development of eating disorders, few studies examine the neural underpinnings of binge eating (BE) in children. Preliminary evidence suggests a role of the corticostriatal system; the purpose of thi…
View article: Distinct attention network topology and dynamics and their relations with pubertal hormones in preadolescent boys and girls with binge eating
Distinct attention network topology and dynamics and their relations with pubertal hormones in preadolescent boys and girls with binge eating Open
The increased prevalence of binge eating during puberty is predominantly in girls, coinciding with a surge in pubertal hormones. This suggests that hormone-activated alterations in widespread brain networks, such as attention network, can …
View article: Phase‐Transitions in Disgust During Self‐Initiated Eating Among Adolescents With Anorexia Nervosa and Related Low‐Weight Eating Disorders and Matched Controls
Phase‐Transitions in Disgust During Self‐Initiated Eating Among Adolescents With Anorexia Nervosa and Related Low‐Weight Eating Disorders and Matched Controls Open
Background Understanding the emotional context of feeding behavior may help identify causal mechanisms of food avoidance among individuals with anorexia nervosa. Although predominant food avoidance models assume fear of fat drives feeding …
View article: Distinct Topological Properties of the Reward Anticipation Network in Preadolescent Children With Binge Eating Disorder Symptoms
Distinct Topological Properties of the Reward Anticipation Network in Preadolescent Children With Binge Eating Disorder Symptoms Open
Binge eating disorder is the most common eating disorder. One factor that may contribute to binge eating is dysregulation of the reward system in the brain. This study analyzed brain activity during anticipation of monetary rewards in 83 y…
View article: Adapting dose–response methodology to improve clinical trial design for psychotherapies
Adapting dose–response methodology to improve clinical trial design for psychotherapies Open
Objective Conventional randomized controlled trials (RCTs) have long served as the foundation of research in clinical psychology; however, most treatments for eating disorders show only modest effects on reduction of symptoms and maintenan…
View article: Development and initial pilot validation of a treatment fidelity instrument for family-based interoceptive exposure for adolescents with low-weight eating disorders
Development and initial pilot validation of a treatment fidelity instrument for family-based interoceptive exposure for adolescents with low-weight eating disorders Open
Background This pilot study outlines the development and psychometric evaluation of a therapist adherence coding measure for a novel treatment, Family-Based Treatment Interoceptive Exposure (FBT-IE). Methods The IE Adherence Coding Framewo…
View article: An exploratory structural equation modelling (<scp>ESEM</scp>) of the Eating Disorders Examination Questionnaire (<scp>EDE‐Q</scp>) in bariatric patients
An exploratory structural equation modelling (<span>ESEM</span>) of the Eating Disorders Examination Questionnaire (<span>EDE‐Q</span>) in bariatric patients Open
Summary Several studies in clinical and non‐clinical populations indicate differences between rationally and empirically derived subscales for the Eating Disorder Examination Questionnaire (EDE‐Q), including samples of patients seeking bar…
View article: A 2.5-Year Weight Management Program Using Noom Health: Protocol for a Randomized Controlled Trial
A 2.5-Year Weight Management Program Using Noom Health: Protocol for a Randomized Controlled Trial Open
Background Overweight and obesity are serious public health concerns. As the prevalence of excess weight among individuals continues to increase, there is a parallel need for inexpensive, highly accessible, and evidence-based weight loss p…
View article: Genome-wide analysis of binge-eating disorder identifies the first three risk loci and implicates iron metabolism
Genome-wide analysis of binge-eating disorder identifies the first three risk loci and implicates iron metabolism Open
Binge-eating disorder (BED) is the most common eating disorder yet its genetic architecture remains largely unknown. Studying BED is challenging because it is often comorbid with obesity, a common and highly polygenic trait, and it is unde…
View article: A Protocol for a 2.5 Year Weight Management using Noom Health: Randomized Controlled Trial (Preprint)
A Protocol for a 2.5 Year Weight Management using Noom Health: Randomized Controlled Trial (Preprint) Open
BACKGROUND Overweight and obesity are serious public health concerns. As the prevalence of excess weight among individuals continues to increase, there is a parallel need for inexpensive, highly accessible, and evidence-based weight loss …
View article: Treatment fidelity in eating disorders and psychological research: Current status and future directions
Treatment fidelity in eating disorders and psychological research: Current status and future directions Open
Objective The evaluation and use of treatment fidelity procedures are rare in the development and implementation of psychological interventions. This article aims to review the construct of treatment fidelity, highlight limitations to curr…
View article: Lessons learned developing and testing <scp>family‐based</scp> interoceptive exposure for adolescents with l<scp>ow‐weight</scp> eating disorders
Lessons learned developing and testing <span>family‐based</span> interoceptive exposure for adolescents with l<span>ow‐weight</span> eating disorders Open
Background Anorexia nervosa (AN) usually develops in early adolescence and is characterized by high rates of morbidity and mortality. Family‐based therapy (FBT) is the leading evidence‐based treatment for adolescents with AN, but not all p…
View article: Patient descriptions of loss of control and eating episode size interact to influence expert diagnosis of ICD-11 binge-eating disorder
Patient descriptions of loss of control and eating episode size interact to influence expert diagnosis of ICD-11 binge-eating disorder Open
Background Although data suggest that the sense of “loss of control” (LOC) is the most salient aspect of binge eating, the definition of LOC varies widely across eating disorder assessments. The WHO ICD-11 diagnostic guidelines for binge e…
View article: Randomized Controlled Trial Comparing Health Coach-Delivered Smartphone-Guided Self-Help With Standard Care for Adults With Binge Eating
Randomized Controlled Trial Comparing Health Coach-Delivered Smartphone-Guided Self-Help With Standard Care for Adults With Binge Eating Open
These results suggest that CBT-GSH plus Noom Monitor delivered via telemedicine by routine-practice health coaches in a nonacademic health care system yields reductions in symptoms and impairment over 52 weeks compared with standard care.
View article: Applying the disgust conditioning model of food avoidance: A case study of acceptance‐based interoceptive exposure
Applying the disgust conditioning model of food avoidance: A case study of acceptance‐based interoceptive exposure Open
Objective The current case report details the treatment of a 16‐year‐old adolescent with anorexia nervosa utilizing a novel adjunct, acceptance‐based interoceptive exposure, prior to family‐based treatment (FBT) for eating disorders. Metho…
View article: 92 Effects of Smartphone Coaching Intervention on Dietary Intake for Bariatric Surgery Candidates: A Pilot Randomized Controlled Trial
92 Effects of Smartphone Coaching Intervention on Dietary Intake for Bariatric Surgery Candidates: A Pilot Randomized Controlled Trial Open
Introduction Bariatric surgery outcomes are variable, often with suboptimal weight loss and/or weight relapse. Smartphone coaching applications offer a potential window of affecting behavioral change to improve outcomes in a widespread and…
View article: Development of a methodology to combine fMRI and EMG to measure emotional responses in patients with anorexia nervosa
Development of a methodology to combine fMRI and EMG to measure emotional responses in patients with anorexia nervosa Open
Objective Individuals with eating disorders are theorized to have basic impairments in affective appraisal and social–emotional processing that contribute to pathogenesis of the disease. We aimed to determine if facial electromyography cou…
View article: Randomized controlled trial comparing smartphone assisted versus traditional guided self‐help for adults with binge eating
Randomized controlled trial comparing smartphone assisted versus traditional guided self‐help for adults with binge eating Open
Objective Guided self‐help treatments based on cognitive‐behavior therapy (CBT‐GSH) are efficacious for binge eating. With limited availability of CBT‐GSH in the community, mobile technology offers a means to increase use of these interven…
View article: Who seeks bariatric surgery? Psychosocial functioning among adolescent candidates, other treatment‐seeking adolescents with obesity and healthy controls
Who seeks bariatric surgery? Psychosocial functioning among adolescent candidates, other treatment‐seeking adolescents with obesity and healthy controls Open
Summary Limited data are available on the characteristics of adolescents with obesity who seek bariatric surgery. Existing data suggest that adolescent surgery candidates have a higher body mass index ( BMI ) than comparison adolescents wi…
View article: Mild, moderate, meaningful? Examining the psychological and functioning correlates of DSM‐5 eating disorder severity specifiers
Mild, moderate, meaningful? Examining the psychological and functioning correlates of DSM‐5 eating disorder severity specifiers Open
Objective This study evaluated the DSM‐5 severity specifiers for treatment‐seeking groups of participants with anorexia nervosa (AN), the purging form of bulimia nervosa (BN), and binge‐eating disorder (BED). Method Hundred and sixty‐two p…
View article: Using Factor Mixture Models to Evaluate the Type A/B Classification of Alcohol Use Disorders in a Heterogeneous Treatment Sample
Using Factor Mixture Models to Evaluate the Type A/B Classification of Alcohol Use Disorders in a Heterogeneous Treatment Sample Open
Background The type A/B classification model for alcohol use disorders ( AUD s) has received considerable empirical support. However, few studies examine the underlying latent structure of this subtyping model, which has been challenged as…