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View article: Progression of Established Atherosclerotic Lesions Is Not Inhibited by Endothelial Knockout of Caveolin-1
Progression of Established Atherosclerotic Lesions Is Not Inhibited by Endothelial Knockout of Caveolin-1 Open
BACKGROUND: Eradicating endothelial caveolae by deleting the Cav1 (caveolin-1) gene reduces LDL (low-density lipoprotein) uptake in arteries and efficiently prevents early atherogenesis, but the role in established atherosclerosis is unkno…
View article: Capacity for LDL (Low-Density Lipoprotein) Retention Predicts the Course of Atherogenesis in the Murine Aortic Arch
Capacity for LDL (Low-Density Lipoprotein) Retention Predicts the Course of Atherogenesis in the Murine Aortic Arch Open
Background: To cause atherosclerosis, LDLs (low-density lipoproteins) must first pass through the endothelium and then become retained in the arterial matrix. Which of these two processes is rate-limiting and predicts the topography of pla…
View article: Targeted endothelial knockout of caveolin-1 in established atherosclerosis does not inhibit plaque progression
Targeted endothelial knockout of caveolin-1 in established atherosclerosis does not inhibit plaque progression Open
Mechanoadaptation & Caveolae Biology Lab, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
View article: Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche
Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche Open
We have described multipotent progenitor-like cells within the major pancreatic ducts (MPDs) of the human pancreas. They express PDX1, its surrogate surface marker P2RY1, and the bone morphogenetic protein (BMP) receptor 1A (BMPR1A)/activi…