Rodica Pădureanu
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View article: Clinical Evaluation of Oxidative Stress Biomarkers in Cirrhosis: Associations with Child–Pugh Class and Hepatic Encephalopathy
Clinical Evaluation of Oxidative Stress Biomarkers in Cirrhosis: Associations with Child–Pugh Class and Hepatic Encephalopathy Open
Background/Objectives: Oxidative stress contributes to the pathogenesis of cirrhosis, but its value as a clinical biomarker remains uncertain. Methods: We retrospectively analysed 90 patients with decompensated cirrhosis. Serum malondialde…
View article: Bone Mineral Density in HIV-Infected People–the Experience of Craiova Regional Center
Bone Mineral Density in HIV-Infected People–the Experience of Craiova Regional Center Open
Background: Human Immunodeficiency Virus (HIV) is a virus that progressively impairs immune function by depleting CD4 + T-lymphocytes, ultimately leading to acquired immunodeficiency syndrome (AIDS). People living with HIV face a higher ri…
View article: Clinical and Evolutive Features of Tuberculous Meningitis in an Immunosuppressed Adolescent During the COVID 19 Pandemic
Clinical and Evolutive Features of Tuberculous Meningitis in an Immunosuppressed Adolescent During the COVID 19 Pandemic Open
Background/Objectives: Tuberculous meningitis is the most severe form of tuberculosis in children, with a high mortality and morbidity rate if it is not diagnosed and treated in a timely manner. The aim of this study is to highlight the ch…
View article: Perspective Chapter: Metabolic Dysfunction-Associated Steatotic Liver Disease as an Emerging Cardiovascular Risk Factor – Pathophysiology, Implications and Clinical Perspectives
Perspective Chapter: Metabolic Dysfunction-Associated Steatotic Liver Disease as an Emerging Cardiovascular Risk Factor – Pathophysiology, Implications and Clinical Perspectives Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease globally and is now recognized as a key cardiometabolic disorder. Beyond hepatic involvement, MASLD is independently a…
View article: Anti-NMDA Receptor Encephalitis: A Narrative Review
Anti-NMDA Receptor Encephalitis: A Narrative Review Open
Antibodies against the NR1 or NR2 subunits of the NMDA receptor are linked to anti-N-methyl-D-aspartate (NMDA) receptor encephalitis, a type of encephalitis that mainly affects women. Clinicians who treat patients of all ages should be awa…
View article: Nephrological, Pulmonary, and Dermatological Complications in the Context of MAFLD/NAFLD: A Narrative Review
Nephrological, Pulmonary, and Dermatological Complications in the Context of MAFLD/NAFLD: A Narrative Review Open
Background: The most common cause of chronic liver disease is now known to be non-alcoholic fatty liver disease (NAFLD), recently redefined as metabolic-associated fatty liver disease (MAFLD). This review aims to synthesize current evidenc…
View article: Complicated Measles in an HIV-Infected Patient—A Case Report and Review of the Literature
Complicated Measles in an HIV-Infected Patient—A Case Report and Review of the Literature Open
Measles remains an important cause of morbidity and mortality worldwide. Most HIV-infected adults are immune against measles, so titres of measles antibodies should be determined prior to vaccination. A measles vaccine can be administered …
View article: Cardiovascular Manifestations of Patients with Non-Alcoholic Fatty Liver Disease
Cardiovascular Manifestations of Patients with Non-Alcoholic Fatty Liver Disease Open
Background: Non-alcoholic fatty liver disease (NAFLD), more recently redefined as metabolic-associated fatty liver disease (MAFLD), is now recognized as the most prevalent cause of chronic liver disease. Its strong association with cardiov…
View article: COPA Syndrome—From Pathogenesis to Treatment
COPA Syndrome—From Pathogenesis to Treatment Open
Coatomer subunit α (COPA) syndrome is a mendelian autosomal dominant immune dysregulation disease characterized by early onset lung disease in the form of diffuse alveolar hemorrhaging or interstitial lung disease, frequently associated wi…
View article: Risk Factors Involved in Postural Disorders in Children and Adolescents
Risk Factors Involved in Postural Disorders in Children and Adolescents Open
Postural disorders in children and adolescents have an increasing incidence. The aim of this study was to identify the type of postural defects in school-age and preschool children, as well as the external risk factors determined by an ina…
View article: Cardiovascular and Neurological Diseases and Association with Helicobacter Pylori Infection—An Overview
Cardiovascular and Neurological Diseases and Association with Helicobacter Pylori Infection—An Overview Open
This article investigates the link between Helicobacter pylori (H. pylori) infection and cardiovascular and neurological disorders. Recent research suggests that H. pylori may play a role in cardiovascular diseases like atherosclerosis, my…
View article: Diagnostic elements in amyotrophic lateral sclerosis: A case report
Diagnostic elements in amyotrophic lateral sclerosis: A case report Open
Amyotrophic lateral sclerosis (ALS) is a rare neurological disease that involves the degeneration of both upper and lower motor neurons responsible for controlling voluntary muscle activity. Most people with ALS die within 3-5 years due to…
View article: The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium
The Role of Neutrophil-to-Lymphocyte Ratio (NLR) in Urosepsis-Associated Delirium Open
Introduction Urosepsis is a systemic, dysregulated, inflammatory reaction to a urinary tract infection and can have severe effects on all systems, which can often lead to multi-organ failure and death. Sepsis-associated delirium is a commo…
View article: Treatment approaches in autoimmune pancreatitis (Review)
Treatment approaches in autoimmune pancreatitis (Review) Open
Autoimmune pancreatitis (AIP) is a rare disease. There are two distinct types of AIP: AIP type 1 (AIP-1), a pancreatic manifestation of a multi-organ disease linked to immunoglobulin (Ig)G4, and AIP type 2 (AIP-2), a pancreas-specific dise…
View article: Clostridium difficile infection in pediatric patients (Review)
Clostridium difficile infection in pediatric patients (Review) Open
Clostridium difficile (C. difficile) infection (CDI) is the most common cause of healthcare-associated diarrhea and among adults, the worldwide incidence rate of the infection is increasing. There is a small amount of data in the literatur…
View article: Prothrombotic status in COVID‑19 with diabetes mellitus (Review)
Prothrombotic status in COVID‑19 with diabetes mellitus (Review) Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused an important social and health impact worldwide and the coronavirus disease-19 (COVID-19) has elicited devastating economy problems. The pathogenesis of SARS…
View article: Quality of life three months post‑stroke among stroke patients and their caregivers in a single center study from Romania during the COVID‑19 pandemic: A prospective study
Quality of life three months post‑stroke among stroke patients and their caregivers in a single center study from Romania during the COVID‑19 pandemic: A prospective study Open
The aim of the present study was to determine the health-related quality of life of stroke patients and their caregivers during the fifth wave of the COVID-19 pandemic. A total of 70 patients who had been diagnosed with stroke between Octo…
View article: Role of the SARS‑COV2 infection in the evolution of acute pancreatitis (Review)
Role of the SARS‑COV2 infection in the evolution of acute pancreatitis (Review) Open
Acute pancreatitis is characterized as an inflammatory illness that is life-threatening and causes necrosis as well as simple edema when pancreatic enzymes are activated intraglandularly. It is not known whether severe acute respiratory sy…
View article: Role of antioxidants and oxidative stress in the evolution of acute pancreatitis (Review)
Role of antioxidants and oxidative stress in the evolution of acute pancreatitis (Review) Open
Acute pancreatitis (AP) is a severe disease with a high prevalence and 3 to 15% mortality worldwide, which can represent an important challenge for the physician. Oxidative stress and antioxidants are involved in AP progression. The mechan…
View article: Neutrophil to Lymphocyte Ratio (NLR)—A Useful Tool for the Prognosis of Sepsis in the ICU
Neutrophil to Lymphocyte Ratio (NLR)—A Useful Tool for the Prognosis of Sepsis in the ICU Open
Sepsis is a life-threatening medical emergency induced by the body′s extreme response to an infection. Despite well-defined and constantly updated criteria for diagnosing sepsis, it is still underdiagnosed worldwide. Among various markers …
View article: New strategies of diagnostic and therapeutic approach to emergencies in the evolution of patients with diabetes mellitus (Review)
New strategies of diagnostic and therapeutic approach to emergencies in the evolution of patients with diabetes mellitus (Review) Open
Diabetes mellitus, known as the most widespread disease in the world, along with four other chronic diseases, involves major expenditures and significant human resources for care, thus representing a burden on any type of health care syste…
View article: Insulin resistance quantified by the value of HOMA‑IR and cardiovascular risk in patients with type 2 diabetes
Insulin resistance quantified by the value of HOMA‑IR and cardiovascular risk in patients with type 2 diabetes Open
Cardiovascular disease (CVD) is recognized as a leading cause of death worldwide. Obesity, dyslipidemia, insulin resistance (IR), interconnected pathological conditions constitute risk factors that are closely associated with CVD. The aim …
View article: Homocysteine as a Predictor Tool in Multiple Sclerosis
Homocysteine as a Predictor Tool in Multiple Sclerosis Open
Multiple sclerosis (MS) is a progressive and irreversible disease which affects the central nervous system (CNS) with still unknown etiology. Our study aimes to establish the homocysteine pattern that can predict the MS diseases progressio…
View article: Non‑alcoholic fatty liver disease and hematologic manifestations (Review)
Non‑alcoholic fatty liver disease and hematologic manifestations (Review) Open
Non-alcoholic fatty liver disease (NAFLD) is a multisystem disease, and it is associated with numerous extra-hepatic manifestations or additional co-occurring diseases. The aim of the present review was the identification and management of…
View article: Rheumatic Immune-Related Adverse Events—A Consequence of Immune Checkpoint Inhibitor Therapy
Rheumatic Immune-Related Adverse Events—A Consequence of Immune Checkpoint Inhibitor Therapy Open
The advent of immunotherapy has changed the management and therapeutic methods for a variety of malignant tumors in the last decade. Unlike traditional cytotoxic chemotherapy, which works by interfering with cancer cell growth via various …
View article: A nontraumatic myositis ossificans case of the forearm: Case report and literature review
A nontraumatic myositis ossificans case of the forearm: Case report and literature review Open
Myositis ossificans (MO) is a rare, benign ossifying lesion characterized by focal formation of heterotopic bone and cartilage in extraskeletal soft-tissue that most commonly occurs in young adults. In most cases, no causative factor can b…
View article: Influence of multidisciplinary therapeutic approach on fibromyalgia patients
Influence of multidisciplinary therapeutic approach on fibromyalgia patients Open
There is no specific cure for fibromyalgia (FM), but combined non-pharmacologic and pharmacologic treatments may mitigate symptoms and improve quality of life in patients. The aim of the present study was to monitor patient response to sev…