Explanipedia

Challenges in the Choice of Nonstatin Medications for Low‐Density Lipoprotein‐C Lowering for Cardiovascular Risk Reduction Open

Merle Myerson, Bruce A. Warden, Joseph J. Saseen, Rodis Paparodis · 2025

Atherosclerotic cardiovascular diseases continue to be a leading cause of death globally. Although statin medications remain the cornerstone of treatment for lowering low‐density lipoprotein cholesterol and reducing cardiovascular risk, th…

A Mixed Model of Clinical Characteristics, Strain Elastography and ACR-TIRADS Predicts Malignancy in Small Thyroid Nodules: A Prospective Single-Center Study Open

Nicholas Angelopoulos, Emmanouil Petropoulos, Ioannis Chrisogonidis, Sarantis Livadas, Rodis Paparodis , et al. · 2025

Background and Objectives: To identify clinical, ultrasound (US) and real-time elastography (RTE) characteristics indicative of malignancy in small thyroid lesions. Materials and Methods: 141 consecutive patients with incidentally discover…

SUN-326 The additive value of real-time elastography to thyroid ultrasound in detecting malignancy in nodules over 20 mm in diameter Open

Nikolaos Angelopoulos, Dimitrios G. Goulis, Sarantis Livadas, Rodis Paparodis, Ioannis P. Androulakis , et al. · 2025

Disclosure: N. Angelopoulos: None. D.G. Goulis: None. S. Livadas: None. R. Paparodis: None. I. Androulakis: None. A. Boniakos: None. J.C. Jaume: None. I. Iakovou: None. Purpose. Ultrasonography (US) is the most accurate and cost-effective …

SUN-119 Thyrotropin values do not affect metabolic and hormonal profile in euthyroid women with PCOS Open

Sarantis Livadas, Nikolaos Angelopoulos, Rodis Paparodis, Jelica Bjekić Macut, Ralitsa Robeva , et al. · 2025

Disclosure: S. Livadas: None. N. Angelopoulos: None. R. Paparodis: None. J. Bjekic Macut: None. R. Robeva: None. J. Kuliczkowska-Płaksej: None. A. Vryonidou: None. G. Mastorakos: None. D. Μacut: None. Introduction: Thyroid function is esse…

SAT-344 The Effect of Preexisting Diabetes on the Risk and Features of Thyroid Cancer in Patients Undergoing Thyroidectomy: An International Multicentric Study Open

Rodis Paparodis, Evangelos Karvounis, George Simeakis, Ioannis Androulakis, Dimitrios Askitis , et al. · 2025

Disclosure: R.D. Paparodis: None. E. Karvounis: None. G. Simeakis: None. I. Androulakis: None. D.P. Askitis: None. S. Livadas: None. A. Rizoulis: None. V. Papanikos: None. N. Mastronikolis: None. D. Zianni: None. C. Massouras: None. I. Per…

SAT-342 Interim Analysis of AIBx Software for Thyroid Cancer Diagnosis from Ultrasound Images. A Multicenter International Study Open

Rodis Paparodis, Andreas Rizoulis, Panagiotis Anagnostis, Juan Carlos Jaume, Dimitrios Askitis , et al. · 2025

Disclosure: R.D. Paparodis: None. A. Rizoulis: None. P. Anagnostis: None. J.C. Jaume: None. D.P. Askitis: None. D. Zianni: None. I. Androulakis: None. N. Angelopoulos: None. S. Livadas: None. A. Boniakos: None. D. Bantouna: None. Y.S. Guer…

MON-807 Vitamin D Deficiency Treatment with Long Term High-Dose Intermittent Dosing Appears Equally Safe and More Effective than Daily Dosing. Open

Rodis Paparodis, Dimitra Bantouna, Nicholas Angelopoulos, Sarantis Livadas, Juan Carlos Jaume , et al. · 2025

Disclosure: R.D. Paparodis: None. D. Bantouna: None. N.G. Angelopoulos: None. S. Livadas: None. J.C. Jaume: None. D.T. Papadimitriou: None. INTRODUCTION Vitamin D deficiency (VDD) (25(OH)D < 30ng/ml) is an extremely common endocrine con…

SAT-343 The Role of Preoperative Titers of Thyroglobulin Antibodies in Thyroid Cancer: Data from a Multicentric International Collaboration Open

Rodis Paparodis, Evangelos Karvounis, George Simeakis, Ioannis Androulakis, Dimitrios Askitis , et al. · 2025

Disclosure: R.D. Paparodis: None. E. Karvounis: None. G. Simeakis: None. I. Androulakis: None. D.P. Askitis: None. S. Livadas: None. A. Rizoulis: None. V. Papanikos: None. N.S. Mastronikolis: None. D. Zianni: None. C. Massouras: None. I. P…

SAT-749 Greek Nationwide Study of HypOPArathyroidism (The OPA study): Preliminary Data on Morbidity, Care Gaps and Treatment Efficacy Open

Rodis Paparodis, Ioannis P. Androulakis, Nicholas Angelopoulos, Dimitrios Askitis, Anastasios Boniakos , et al. · 2025

Disclosure: R.D. Paparodis: None. I. Androulakis: None. N.G. Angelopoulos: None. D.P. Askitis: None. A. Boniakos: None. A. Rizoulis: None. D. Zianni: None. G. Simeakis: None. D.T. Papadimitriou: None. S. Livadas: None. J.C. Jaume: None. In…

Integrating Clinical Parameters into Thyroid Nodule Malignancy Risk: A Retrospective Evaluation Based on ACR TI-RADS Open

Nicholas Angelopoulos, Ioannis Androulakis, Dimitrios Askitis, Nicolas Valvis, Rodis Paparodis , et al. · 2025

Background/Objectives: Thyroid nodules are commonly found through sensitive imaging methods like ultrasonography. While most nodules are benign and asymptomatic, certain characteristics may indicate malignancy, prompting fine needle aspira…

Dramatic Deterioration of Subclinical Hyperparathyroidism in Children and Adolescents During the Post-COVID-19 Period Open

Maria Loutsou, Eleni Dermitzaki, Rodis Paparodis, Aspasia N. Michoula, Nicholas Angelopoulos , et al. · 2025

Background: Vitamin D is a steroid hormone, essential for the immune system and bone health. Since the sun is meant to provide at least 80% of daily vitamin D requirements, the COVID-19 pandemic is likely to have induced a considerable inf…

Conversion of T Effector Cells Into T Regulatory Cells in Type 1 Diabetes/Latent Autoimmune Diabetes of Adults by Inhibiting eIF5A and Notch Pathways Open

Shafiya Imtiaz Rafiqi, Ahmad Aldasouqi, Rodis Paparodis, Sandesh Dewan, Aneeba Farooqi , et al. · 2025

A unique population of proinflammatory cytokines expressing intermediate Tregs (CD4⁺CD25^-IFNg⁺IL17⁺FOXP3⁺) was characterized in T1D/LADA patients and found significantly increased comp…

Effects of a Novel Dispersible Supplement Containing 2500 IU of Vitamin D and 1000 µg of B12 in Restoring Vitamin D and B12 Insufficiency: A Multicenter, Randomized Controlled Trial Open

Nicholas Angelopoulos, Rodis Paparodis, Ioannis P. Androulakis, Anastasios Boniakos, Sarantis Livadas · 2025

Background/Objectives: Vitamins D and B12 play a crucial role in maintaining bone health, immune function, and neurological integrity. Combined deficiencies in these vitamins can lead to severe health consequences. Current treatment approa…

Radiofrequency Ablation for Locoregional Structural Incomplete Response in Differentiated Thyroid Cancer: Initial Experience in Greece Open

George Simeakis, Aikaterini Kapama, Rodis Paparodis, Pyrros Gkousis, Panayiotis Koursaros , et al. · 2025

Background/Objectives: Structural incomplete response (SIR) (persistence/recurrence) may occur in 2–6% of low-risk differentiated thyroid cancer (DTC)-cases and in 67–75% of high risk. Regarding locoregional disease, surgery is the optimal…

Radiofrequency Ablation for Locoregional Structural Incomplete Response in Differentiated Thyroid Cancer; initial experience in Greece Open

George Simeakis, Aikaterini Kapama, Rodis Paparodis, Pyrros Gkousis, Panayiotis Koursaros , et al. · 2024

Background/Objectives: Structural incomplete response (SIR) (persistence/recurrence) may occur in 2-6% of low-risk differentiated thyroid cancer (DTC)-cases and in 67-75% of high-risk. Regarding locoregional disease, surgery is the optimal…

7466 The Effects of Various Forms of Diabetes on Features of Tumor Aggressiveness in Thyroid Cancer Open

Rodis Paparodis, Evangelos Karvounis, Aikaterini Kapezanou, Sarantis Livadas, George Simeakis , et al. · 2024

Disclosure: R.D. Paparodis: None. E. Karvounis: None. A. Kapezanou: None. S. Livadas: None. G. Simeakis: None. D.P. Askitis: None. I. Androulakis: None. N.G. Angelopoulos: None. D. Zianni: None. A. Rizoulis: None. A. Boniakos: None. I. Per…

7642 A Mixed Model of Clinical Characteristics and Ultrasound ACR-TIRADS Predicts Malignancy in Thyroid Micro Lesions Open

Nikolaos Angelopoulos, Ιoannis Iakovou, Dimitrios G. Goulis, Rodis Paparodis, Sarantis Livadas , et al. · 2024

Disclosure: N. Angelopoulos: None. I. Iakovou: None. D. Goulis: None. R. Paparodis: None. S. Livadas: None. A. Boniakos: None. J.C. Jaume: None. Background: The frequency of papillary thyroid carcinoma (PTC) has increased, mainly due to th…

7466 The Effects Of Various Forms Of Diabetes On Features Of Tumor Aggressiveness In Thyroid Cancer Open

Rodis Paparodis, Evangelos Karvounis, Aikaterini Kapezanou, Sarantis Livadas, George Simeakis , et al. · 2024

Disclosure: R.D. Paparodis: None. E. Karvounis: None. A. Kapezanou: None. S. Livadas: None. G. Simeakis: None. D.P. Askitis: None. I. Androulakis: None. N.G. Angelopoulos: None. D. Zianni: None. A. Rizoulis: None. A. Boniakos: None. I. Per…

7144 Lack of TPO Antibodies Heralds “Immune Escape” of Aggressive Thyroid Cancers of Follicular Origin: An International Retrospective Analysis of 1,943 Consecutive Thyroidectomy Cases Open

Rodis Paparodis, Evangelos Karvounis, Aikaterini Kapezanou, Dimitra Bantouna, Sarantis Livadas , et al. · 2024

Disclosure: R.D. Paparodis: None. E. Karvounis: None. A. Kapezanou: None. D. Bantouna: None. S. Livadas: None. G. Simeakis: None. D.P. Askitis: None. I. Androulakis: None. N.G. Angelopoulos: None. D. Zianni: None. I. Perogamvros: None. A. …

7175 Vitamin D Restoration with a Treat-To-Goal Clinical Strategy: A Retrospective, Quality of Care, Controlled Study of 3,871 Cases in a Real-World Setting Open

Dimitra Bantouna, Nicholas Angelopoulos, Sarantis Livadas, Juan Carlos Jaume, Evangelos Karvounis , et al. · 2024

Disclosure: D. Bantouna: None. N.G. Angelopoulos: None. S. Livadas: None. J.C. Jaume: None. E. Karvounis: None. D.T. Papadimitriou: None. S. Karras: None. R.D. Paparodis: None. Introduction: Vitamin D deficiency (VDD) (< 30ng/ml) is a g…

7144 Lack Of TPO Antibodies Heralds “Immune Escape” Of Aggressive Thyroid Cancers Of Follicular Origin: An International Retrospective Analysis Of 1,943 Consecutive Thyroidectomy Cases Open

Rodis Paparodis, Evangelos Karvounis, Aikaterini Kapezanou, Dimitra Bantouna, Sarantis Livadas , et al. · 2024

Disclosure: R.D. Paparodis: None. E. Karvounis: None. A. Kapezanou: None. D. Bantouna: None. S. Livadas: None. G. Simeakis: None. D.P. Askitis: None. I. Androulakis: None. N.G. Angelopoulos: None. D. Zianni: None. I. Perogamvros: None. A. …

12622 Molecular Physiology And Compensatory Response In Maladapted Pancreatic Islets Of Humanized Mice Model For Type 1 Diabetes Open

Ashaq Hussain, Ahmad Aldasouqi, Shafiya Imtiaz Rafiqi, Saira Khan, Rodis Paparodis , et al. · 2024

Disclosure: A. Hussain: None. A. Aldasouqi: None. S. Rafiqi: None. S.S. Khan: None. R. Paparodis: None. J.C. Jaume: None. S. Imam: None. Genetic predisposition linked with specific HLA (DR and DQ) alleles, environmental factors, and other …

Secondary Cardiovascular Disease Prevention Deficit Persists over the Years: A Multicenter Cross-Sectional Study Involving 1003 Consecutive Patients from Greece Open

Rodis Paparodis, Ioannis Androulakis, Dimitrios Askitis, Ilias Perogamvros, Nicholas Angelopoulos , et al. · 2024

Purpose: Lipid lowering treatments (LLTs) can reduce the risk of atherosclerotic cardiovascular disease (ASCVD). Despite the availability of potent LLTs, our clinical observations suggest an inadequate use of such agents. To evaluate this …

Hypercalcemic Crisis Due to a Giant Intrathyroidal Parathyroid Adenoma, with Postsurgical Severe Hypocalcemia and Hungry Bone Syndrome: A Case Report Open

Vasileios Papanikos, Elli Papadodima, Dimitra Bantouna, Rodis Paparodis, Sarantis Livadas , et al. · 2024

Background: Parathyroid adenoma is the most common cause of hypercalcemia and rarely leads to a hypercalcemic crisis, which is an unusual endocrine emergency that requires timely surgical excision. Case presentation: A 67-year-old male was…

Intense Testing and Use of Vitamin D Supplements Leads to Slow Improvement in Vitamin D Adequacy Rates: A Cross-Sectional Analysis of Real-World Data Open

Rodis Paparodis, Dimitra Bantouna, Evangelos Karvounis, Ioannis Zoupas, Sarantis Livadas , et al. · 2023

Background: Vitamin D testing (VDT) and supplement use (VDS) are on the rise, but most patients remain deficient (3000 IU/day)), intake duration (short-term (<12 months) and long-term use (≥12 months)), and timing of use (current use, form…

A Nutritional Approach to Optimizing Pump Therapy in Type 1 Diabetes Mellitus Open

Evdoxia Gitsi, Sarantis Livadas, Nicholas Angelopoulos, Rodis Paparodis, Marina Raftopoulou , et al. · 2023

Achieving optimal glucose control in individuals with type 1 diabetes (T1DM) continues to pose a significant challenge. While continuous insulin infusion systems have shown promise as an alternative to conventional insulin therapy, there r…

Clinical Aspects in Subacute Thyroiditis: A Real-Life Study on 226 Cases in Greece Amid the COVID-19 Pandemic Open

Nicholas Angelopoulos, Dimitrios Askitis, Ioannis P. Androulakis, Nicolas Valvis, Rodis Paparodis , et al. · 2023

Purpose: This study aimed to evaluate various therapeutic approaches, identify potential predictive factors for the recurrence and development of hypothyroidism, and examine specific clinical and laboratory characteristics of patients with…

FRI085 Lipid Lowering Therapy Deficits In Secondary Cardiovascular Prevention In A Large Cohort From Eight Busy Clinics In Greece Over 12 Years Open

Rodis Paparodis, Ioannis Androulakis, Dimitrios Askitis, Ilias Perogamvros, Nikolaos Angelopoulos , et al. · 2023

Disclosure: R.D. Paparodis: None. I. Androulakis: None. D.P. Askitis: None. I. Perogamvros: None. N. Angelopoulos: None. A. Rizoulis: None. S. Livadas: None. A. Boniakos: None. Background: The increasing availability of aggressive lipid lo…

FRI469 Natural History Of de Quervain’s Thyroiditis In The Era Of COVID -19: The Greek Experience Of 226 Cases Open

Nikolaos Angelopoulos, Dimitrios Askitis, Ioannis P. Androulakis, Nicolas Valvis, Rodis Paparodis , et al. · 2023

Disclosure: N. Angelopoulos: None. D.P. Askitis: None. I. Androulakis: None. N. Valvis: None. R. Paparodis: None. V. Petkova: None. A. Boniakos: None. D. Zianni: None. I. Perogamvros: None. K.A. Toulis: None. S. Livadas: None. Background: …

THU399 Increasing Testing And Use Of Vitamin D Supplements Leads To Slow Progress In Restoring Vitamin D Adequacy: An Interim Analysis Of The "Vitamin D Deficiency In Western Greece" Real World Data Study Open

Rodis Paparodis, Dimitra Bantouna, Evangelos Karvounis, Sarantis Livadas, Nicholas Angelopoulos , et al. · 2023

Disclosure: R.D. Paparodis: None. D. Bantouna: None. E. Karvounis: None. S. Livadas: None. N.G. Angelopoulos: None. I. Zoupas: None. S. Imam: None. J.C. Jaume: None. Introduction: Vitamin D testing and use of supplements (VDS) has been ris…

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