Rodrigo Cuenca
YOU?
Author Swipe
View article: Dual-excitation multispectral fluorescence lifetime imaging handheld endoscope for label-free metabolic and biochemical imaging of the oral mucosa
Dual-excitation multispectral fluorescence lifetime imaging handheld endoscope for label-free metabolic and biochemical imaging of the oral mucosa Open
This work introduces a dual-excitation, multispectral-detection, frequency-domain fluorescence lifetime imaging (FLIM) handheld endoscopy system for comprehensive autofluorescence imaging of the oral mucosa. The excitation wavelengths and …
View article: Contrastive Clustering-Based Patient Normalization to Improve Automated In Vivo Oral Cancer Diagnosis from Multispectral Autofluorescence Lifetime Images
Contrastive Clustering-Based Patient Normalization to Improve Automated In Vivo Oral Cancer Diagnosis from Multispectral Autofluorescence Lifetime Images Open
Background: Multispectral autofluorescence lifetime imaging systems have recently been developed to quickly and non-invasively assess tissue properties for applications in oral cancer diagnosis. As a non-traditional imaging modality, the a…
View article: Computer-assisted discrimination of cancerous and pre-cancerous from benign oral lesions based on multispectral autofluorescence imaging endoscopy
Computer-assisted discrimination of cancerous and pre-cancerous from benign oral lesions based on multispectral autofluorescence imaging endoscopy Open
This study demonstrates the potentials of a computer-assisted detection system based on multispectral autofluorescence imaging endoscopy for the early detection of cancerous and precancerous oral lesions.
View article: Aligning Small Datasets Using Domain Adversarial Learning: Applications in Automated in Vivo Oral Cancer Diagnosis
Aligning Small Datasets Using Domain Adversarial Learning: Applications in Automated in Vivo Oral Cancer Diagnosis Open
Deep learning approaches for medical image analysis are limited by small data set size due to factors such as patient privacy and difficulties in obtaining expert labelling for each image. In medical imaging system development pipelines, p…
View article: Clinical label-free endoscopic imaging of biochemical and metabolic autofluorescence biomarkers of benign, precancerous, and cancerous oral lesions
Clinical label-free endoscopic imaging of biochemical and metabolic autofluorescence biomarkers of benign, precancerous, and cancerous oral lesions Open
Early detection is critical for improving the survival rate and quality of life of oral cancer patients; unfortunately, dysplastic and early-stage cancerous oral lesions are often difficult to distinguish from oral benign lesions during st…
View article: Machine-Learning Assisted Discrimination of Precancerous and Cancerous from Healthy Oral Tissue Based on Multispectral Autofluorescence Lifetime Imaging Endoscopy
Machine-Learning Assisted Discrimination of Precancerous and Cancerous from Healthy Oral Tissue Based on Multispectral Autofluorescence Lifetime Imaging Endoscopy Open
Multispectral autofluorescence lifetime imaging (maFLIM) can be used to clinically image a plurality of metabolic and biochemical autofluorescence biomarkers of oral epithelial dysplasia and cancer. This study tested the hypothesis that ma…
View article: Handheld tunable focus confocal microscope utilizing a double-clad fiber coupler for <i>in vivo</i> imaging of oral epithelium
Handheld tunable focus confocal microscope utilizing a double-clad fiber coupler for <i>in vivo</i> imaging of oral epithelium Open
A reflectance confocal endomicroscope with double-clad fiber coupler and electrically tunable focus lens is applied to imaging of the oral mucosa. The instrument is designed to be lightweight and robust for clinical use. The tunable lens a…
View article: Objective Detection of Oral Carcinoma with Multispectral Fluorescence Lifetime Imaging <i>In Vivo</i>
Objective Detection of Oral Carcinoma with Multispectral Fluorescence Lifetime Imaging <i>In Vivo</i> Open
Successful early detection and demarcation of oral carcinoma can greatly impact the associated morbidity and mortality rates. Current methods for detection of oral cancer include comprehensive visual examination of the oral cavity, typical…
View article: A novel multimodal optical imaging system for early detection of oral cancer
A novel multimodal optical imaging system for early detection of oral cancer Open