Rohan Bir Singh
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View article: Current Landscape and Future Prospects of Corneal Regenerative Medicine
Current Landscape and Future Prospects of Corneal Regenerative Medicine Open
Corneal disorders are among the leading causes of visual impairment worldwide, with corneal transplantation historically serving as the cornerstone of surgical treatment. However, the global shortage of donor tissue, risk of immune rejecti…
View article: Prevalence of Age-Related Macular Degeneration (AMD) in the United States: A Medicare-Based Analysis from 2014 to 2021.
Prevalence of Age-Related Macular Degeneration (AMD) in the United States: A Medicare-Based Analysis from 2014 to 2021. Open
Purpose: To assess the prevalence of age-related macular degeneration (AMD) among U.S. individuals aged 65 years and older. Design: Retrospective cohort study using data from the Vision and Eye Health Surveillance System (VEHSS), which inc…
View article: Clinical characteristics and treatment patterns of elderly patients living with Mantle Cell Lymphoma
Clinical characteristics and treatment patterns of elderly patients living with Mantle Cell Lymphoma Open
Background: Mantle Cell Lymphoma (MCL) is an incurable subtype of non-Hodgkin lymphoma with a median age of 68 yrs at diagnosis. While clinical trials have historically divided patients with MCL by eligibility for autologous stem cell tran…
View article: Effect of finisher Gentlefile Brush, XP-Endo Finisher and Passive Ultrasonic Irrigation in removing radiopaque double antibiotic paste from the root canal
Effect of finisher Gentlefile Brush, XP-Endo Finisher and Passive Ultrasonic Irrigation in removing radiopaque double antibiotic paste from the root canal Open
The complete elimination of double antibiotic paste (DAP) before obturation is a critical clinical challenge in endodontics. This study evaluated three systems for removing radiopaque DAP from root canals. After being instrumented and fill…
View article: Global Burden, Risk Factors, Causative Organisms and Antibiotic Susceptibility Patterns in Bacterial Keratitis
Global Burden, Risk Factors, Causative Organisms and Antibiotic Susceptibility Patterns in Bacterial Keratitis Open
Summary Background Bacterial keratitis (BK) is a leading cause of corneal ulceration and vision loss worldwide. We aimed to synthesize global data on BK prevalence, risk factors, causative pathogens, and antibiotic susceptibility through a…
View article: Orthopedic Surgery Residency Match Trends in 2024: Step Scores and Research on the Rise
Orthopedic Surgery Residency Match Trends in 2024: Step Scores and Research on the Rise Open
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View article: Prevalence, Demographics, and Mortality/Morbidity of Thrombotic Events: A nationwide study of SLE patients in the United States
Prevalence, Demographics, and Mortality/Morbidity of Thrombotic Events: A nationwide study of SLE patients in the United States Open
Background: Thromboembolic events (TE) cause significant morbidity and mortality in SLE patients. Comprehensive data on various types of thromboembolic events and their variation by gender, region, and hospital status are scant. Objective:…
View article: Personalized glucose prediction using in situ data only
Personalized glucose prediction using in situ data only Open
The worldwide rise in blood glucose levels is a major health concern, as various metabolic diseases become increasingly common. Diet, a modifiable health behaviour, is a primary target for the preventive management of glucose levels. Recen…
View article: Amniotic Membrane Transplantation for Wound Healing, Tissue Regeneration and Immune Modulation
Amniotic Membrane Transplantation for Wound Healing, Tissue Regeneration and Immune Modulation Open
View article: Clinical Efficacy of Ex Vivo Cross-Linking on Neovascularization of the Donor Cornea Carrier Tissue for the Boston Type I Keratoprosthesis
Clinical Efficacy of Ex Vivo Cross-Linking on Neovascularization of the Donor Cornea Carrier Tissue for the Boston Type I Keratoprosthesis Open
View article: Künstliche Intelligenz (KI) zur Früherkennung von Netzhauterkrankungen
Künstliche Intelligenz (KI) zur Früherkennung von Netzhauterkrankungen Open
Künstliche Intelligenz (KI) hat sich zu einem transformativen Werkzeug auf dem Gebiet der Augenheilkunde entwickelt und revolutioniert die Diagnose und Behandlung von Krankheiten. Diese Arbeit gibt einen umfassenden Überblick über KI-Anwen…
View article: Readability of Hospital Online Patient Education Materials Across Otolaryngology Specialties
Readability of Hospital Online Patient Education Materials Across Otolaryngology Specialties Open
Introduction This study evaluates the readability of online patient education materials (OPEMs) across otolaryngology subspecialties, hospital characteristics, and national otolaryngology organizations, while assessing AI alternatives. Met…
View article: Antioxidants in Age-Related Macular Degeneration: Lights and Shadows
Antioxidants in Age-Related Macular Degeneration: Lights and Shadows Open
Age-related macular degeneration (AMD) is a leading cause of vision impairment worldwide, primarily driven by oxidative stress and inflammation. This review examines the role of antioxidants in mitigating oxidative damage, emphasizing both…
View article: Comparative Assessment of Vital Physiological Parameters FollowingVarious Feeding Techniques in Preterm Neonates
Comparative Assessment of Vital Physiological Parameters FollowingVarious Feeding Techniques in Preterm Neonates Open
Background: Feeding preterm neonates poses unique challenges due to their immature physiological systems.Various feeding methods such as gavage, spoon, and paladai feeding are commonly employed in neonatalintensive care units (NICUs). Thes…
View article: Assessment of central and peripheral contrast sensitivity in myopes using Spaeth/Richman contrast sensitivity
Assessment of central and peripheral contrast sensitivity in myopes using Spaeth/Richman contrast sensitivity Open
BACKGROUND: Assessing central and peripheral contrast sensitivity (CS) in myopic patients with varying degrees of refractive error using Spaeth/Richman contrast sensitivity test (SPARCS) and compared it with emmetropic individuals. MATERIA…
View article: Pulmonary lymphangitic carcinomatosis mimicking interstitial lung disease
Pulmonary lymphangitic carcinomatosis mimicking interstitial lung disease Open
View article: Utility of ChatGPT as a preparation tool for the Orthopaedic In‐Training Examination
Utility of ChatGPT as a preparation tool for the Orthopaedic In‐Training Examination Open
Purpose Chat Generative Pre‐Trained Transformer (ChatGPT) may have implications as a novel educational resource. There are differences in opinion on the best resource for the Orthopaedic In‐Training Exam (OITE) as information changes from …
View article: Spinal accessory nerve transfer for shoulder abduction has no benefit over supraclavicular exploration and nerve grafting in brachial plexus birth injury: a systematic review
Spinal accessory nerve transfer for shoulder abduction has no benefit over supraclavicular exploration and nerve grafting in brachial plexus birth injury: a systematic review Open
Introduction Brachial plexus birth injury (BPBI) has an incidence of 0.9 per 1,000 live births in the population. Techniques for repair classically include supraclavicular exploration and nerve grafting (SENG) and more recently nerve trans…
View article: Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention
Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention Open
Refractive errors, particularly myopia, are among the most prevalent visual impairments globally, with rising incidence in children and adolescents. This review explores the epidemiology and risk factors associated with the development of …
View article: Increased Serum Vitamin D and Decreased Serum Cholesterol Are Associated with Development of Squamous Cell Carcinoma in Actinic Keratosis Patients: A Retrospective Machine-Learning Analysis of the All of Us Database
Increased Serum Vitamin D and Decreased Serum Cholesterol Are Associated with Development of Squamous Cell Carcinoma in Actinic Keratosis Patients: A Retrospective Machine-Learning Analysis of the All of Us Database Open
View article: Acquired immunostimulatory phenotype of migratory CD103+ DCs promotes alloimmunity following corneal transplantation
Acquired immunostimulatory phenotype of migratory CD103+ DCs promotes alloimmunity following corneal transplantation Open
After transplantation, Th1-mediated immune rejection is the predominant cause of graft failure. Th1 cell sensitization occurs through complex and context-dependent interaction among antigen-presenting cell subsets, particularly CD11b+ DCs …
View article: Minimum Days Estimation for Reliable Dietary Intake Information: Findings from a Digital Cohort
Minimum Days Estimation for Reliable Dietary Intake Information: Findings from a Digital Cohort Open
Accurate dietary assessment is crucial for understanding diet-health relationships, but variability in daily food intake poses challenges in capturing precise data. This study leveraged data from 958 participants of the “Food & You“ digita…
View article: Assessment of Corneal Graft Outcomes in a Murine Model of Endothelial Keratoplasty
Assessment of Corneal Graft Outcomes in a Murine Model of Endothelial Keratoplasty Open
Objectives: In this study, we establish a protocol for evaluating the outcomes of endothelial keratoplasty, including graft survival, rejection, or failure. Additionally, we also evaluate the alloimmune response in graft recipients. Method…
View article: Neuropeptide alpha-Melanocyte stimulating hormone preserves corneal endothelial morphology in a murine model of Fuchs dystrophy
Neuropeptide alpha-Melanocyte stimulating hormone preserves corneal endothelial morphology in a murine model of Fuchs dystrophy Open
View article: Potential applications of mesenchymal stem cells in ocular surface immune-mediated disorders
Potential applications of mesenchymal stem cells in ocular surface immune-mediated disorders Open
View article: Ocular Implications of COVID-19 Infection and Vaccine-Related Adverse Events
Ocular Implications of COVID-19 Infection and Vaccine-Related Adverse Events Open
The COVID-19 pandemic, caused by SARS-CoV-2, has significantly impacted various organ systems, including the eyes. Initially considered a primarily respiratory disease, it is now evident that COVID-19 can induce a range of ocular symptoms.…
View article: Thyroid Eye Disease: Advancements in Orbital and Ocular Pathology Management
Thyroid Eye Disease: Advancements in Orbital and Ocular Pathology Management Open
Thyroid Eye Disease (TED) is a debilitating autoimmune condition often associated with thyroid dysfunction, leading to significant ocular and orbital morbidity. This review explores recent advancements in the management of TED, focusing on…
View article: Whole-eye transplantation: Current challenges and future perspectives
Whole-eye transplantation: Current challenges and future perspectives Open
Whole-eye transplantation emerges as a frontier in ophthalmology, promising a transformative approach to irreversible blindness. Despite advancements, formidable challenges persist. Preservation of donor eye viability post-enucleation nece…
View article: Personalized glucose prediction using in situ data only
Personalized glucose prediction using in situ data only Open
The worldwide rise in blood glucose levels is a major health concern, as various metabolic diseases become increasingly common. Diet, a modifiable health behavior, is a primary target for the preventive management of glucose levels. Recent…
View article: The Comparative Diagnostic Capability of Large Language Models in Otolaryngology
The Comparative Diagnostic Capability of Large Language Models in Otolaryngology Open
Objectives Evaluate and compare the ability of large language models (LLMs) to diagnose various ailments in otolaryngology. Methods We collected all 100 clinical vignettes from the second edition of Otolaryngology Cases—The University of C…