Explanipedia

Survey of the International Pain and Spine Interventional Society on Genicular Nerve Radiofrequency Treatment Open

Shawn Fernandez, Reza Ehsanian, Amanda Cooper, Daniel M. Cushman, Rohit Aiyer , et al. · 2025

Genicular nerve radiofrequency ablation practice patterns: A survey study of the International Pain and Spine Interventional Society Open

Reza Ehsanian, Shawn Fernandez, Amanda Cooper, Daniel M. Cushman, Aaron Conger , et al. · 2024

Effectiveness of Erector Spinae Plane Block as Perioperative Analgesia in Midline Sternotomies: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open

Nimesh Patel, Mohamed Fayed, Wissam Maroun, Hannah Milad, Katie Adlaka , et al. · 2024

With the advancements in regional anesthesia and ultrasound techniques, the use of non-neuraxial blocks like the erector spinae plane block (ESPB) has been increasing in cardiac surgeries with promising outcomes. A total of 3,264 articles …

Artificial Intelligence and Pain Medicine: An Introduction Open

Jonathan M. Hagedorn, Tony K. George, Rohit Aiyer, Keith T. Schmidt, John Halamka , et al. · 2024

Artificial intelligence was introduced 60 years ago and has evolved immensely since that time. While artificial intelligence is found in nearly all aspects of our life, the use of artificial intelligence in the healthcare industry has only…

Transcranial magnetic stimulation for the treatment of chronic low back pain: a narrative review Open

Camille Olechowski, Maricar Gener, Rohit Aiyer, Nicholas Mischel · 2023

Background Chronic low back pain is a debilitating condition that impacts millions of individuals around the world, and also has an enormous economic impact. The impact of chronic pain does not only involve physical health, but can also pl…

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain Open

Dawood Sayed, Jay S. Grider, Natalie Strand, Jonathan M. Hagedorn, Steven Falowski , et al. · 2022

The ASPN Back Guideline represents the first comprehensive analysis and grading of the existing and emerging interventional treatments available for low back pain. This will be a living document which will be periodically updated to the cu…

The American Society of Pain and Neuroscience (ASPN) Evidence-Based Clinical Guideline of Interventional Treatments for Low Back Pain [Corrigendum] Open

Dawood Sayed, Jay Grider, Natalie Strand, Jonathan M. Hagedorn, Steven Falowski , et al. · 2022

[This corrects the article DOI: 10.2147/JPR.S386879.].

Balloon Kyphoplasty vs Vertebroplasty: A Systematic Review of Height Restoration in Osteoporotic Vertebral Compression Fractures Open

Nimesh Patel, David R. Jacobs, Jessin John, Mohamed Fayed, Lakshmi Akhila Nerusu , et al. · 2022

Balloon kyphoplasty and vertebroplasty are effective treatments for vertebral compression fractures and this review suggests that balloon kyphoplasty may be favored for vertebral height restoration. Further studies are needed to conclude w…

Corrigendum to: A Systematic Literature Review of Spine Neurostimulation Therapies for the Treatment of Pain Open

Timothy R. Deer, Jay S. Grider, Tim J. Lamer, Jason E. Pope, Steven Falowski , et al. · 2020

A Systematic Literature Review of Dorsal Root Ganglion Neurostimulation for the Treatment of Pain Open

Timothy R. Deer, Corey Hunter, Pankaj Mehta, Dawood Sayed, Jay S. Grider , et al. · 2020

Objective To conduct a systematic literature review of dorsal root ganglion (DRG) stimulation for pain. Design Grade the evidence for DRG stimulation. Methods An international, interdisciplinary work group conducted a literature search for…

A Systematic Literature Review of Peripheral Nerve Stimulation Therapies for the Treatment of Pain Open

Timothy R. Deer, Michael Esposito, W. Porter McRoberts, Jay S. Grider, Dawood Sayed , et al. · 2020

Objective To conduct a systematic literature review of peripheral nerve stimulation (PNS) for pain. Design Grade the evidence for PNS. Methods An international interdisciplinary work group conducted a literature search for PNS. Abstracts w…

A Systematic Literature Review of Spine Neurostimulation Therapies for the Treatment of Pain Open

Timothy R. Deer, Jay S. Grider, Tim J. Lamer, Jason E. Pope, Steven Falowski , et al. · 2019

Objective To conduct a systematic literature review of spinal cord stimulation (SCS) for pain. Design Grade the evidence for SCS. Methods An international, interdisciplinary work group conducted literature searches, reviewed abstracts, and…

Incidence and risk factors for development of persistent postsurgical pain following total knee arthroplasty Open

Semih Güngör, Kara G. Fields, Rohit Aiyer, Alejandro González Della Valle, Edwin P. Su · 2019

Persistent postsurgical pain (PPP) is defined as the discomfort that lasts >3 months postoperatively. The primary aim of this retrospective study was to estimate the risk of developing moderate-to-severe PPP after primary total knee arthro…

Extrapyramidal signs occurring after sympathetic block for complex regional pain syndrome responding to diphenhydramine Open

Semih Güngör, Rohit Aiyer · 2018

Sympathetic blockade may interfere with the adaptive autonomic reflex circuits of the motor balance homeostasis in patients with complex regional pain syndrome. Disinhibition of extrapyramidal system may lead to immediate expression of ext…

Sympathetic blocks for the treatment of complex regional pain syndrome Open

Semih Güngör, Rohit Aiyer, Buse Baykoca-Arslan · 2018

Treatment options are limited and there is lack of high quality research regarding the efficacy of sympathetic blocks in the treatment of complex regional pain syndrome. As presented in this case series, sympathetic blocks maybe very effec…

Pyogenic Odontoid Osteomyelitis with Sinus Thrombosis Open

Rohit Aiyer, Janice Hwang, Edward H. Yu · 2017

71/F presented with left sided headaches and neck pain with nuchal rigidity progressively worsening over 3 weeks with no other neurologic symptoms. Odontoid osteomyelitis with epidural abscess was discovered on further workup with neuroima…

Treatment of Neuropathic Pain with Venlafaxine: A Systematic Review Open

Rohit Aiyer, Robert L. Barkin, Anurag Bhatia · 2016

Objective To investigate the efficacy of venlafaxine for neuropathic pain and review literature to determine if the medication provides adequate neuropathic pain relief. Methods Literature was reviewed on MEDLINE using various key words. T…

An Overview of Arachnoid Webs Open

Rohit Aiyer · 2016

Arachnoid webs are abnormal formations of arachnoid membrane in the spinal subarachnoid space that prevents movement of cerebrospinal fluid (CSF) in the longitudinal direction 1 .These webs represent intradural extramedullary transverse ba…

Dorsal thoracic arachnoid web presenting as neuropathic pain: ‘Scalpel’ sign found on MRI Open

Rohit Aiyer, Yasir El‐Sherif, L. Voutsinas · 2016

Dorsal thoracic arachnoid webs are due to a deformity in the formation of arachnoid membrane in the spinal arachnoid space. These webs usually occur in the upper thoracic spine and are viewed on imaging as a pathogonomic ‘scalpel’ sign bec…

Dysphagia and anorexia as presentations of leptomeningeal carcinomatosis Open

Rohit Aiyer, Ester Engelman, Wei Xue, Edward H. Yu · 2016

A 61-year-old woman presented to the emergency department, with a 4-day history of isolated oropharyngeal dysphagia associated with anorexia and weight loss over the previous 4 weeks. She had no other focal neurological symptoms and no def…

Does health-related content in a major Ugandan newspaper reflect the changing burden of disease in East Africa? Open

Max Cooper, Rohit Aiyer, Sangeetha Sornalingam, David Lawrence · 2016

Disease burden in urban sub-Saharan Africa is changing rapidly. Mortality and morbidity from chronic physical disease (e.g. heart, disease, stroke and cancer) is rising rapidly and believed to be as great as from infections (e.g. malaria, …

Rare Case of Posterior Reversible Leukoencephalopathy Syndrome Secondary to Acute Chest Syndrome Open

Rohit Aiyer, Daniel Klein, Yasir El‐Sherif · 2016

We present a case of 29/m with a history of sickle cell disease who presented to the emergency department with sudden onset of chest, trunk, extremity, and back pain, consistent in quality and severity with the patient’s usual pain crises.…

Valproic Acid Induced Hyperammonemia in a Long Time Treated Patient Open

Rohit Aiyer, Margaret Seide, Robert G. Stern · 2016

We report a case of a patient who had been on long time valproic acid for treatment of bipolar affective disorder. While being an inpatient, serology ammonia level testing revealed a very high ammonia level despite being asymptomatic. Dual…

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