Rohit Doke
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View article: Polymeric Nanoparticles, Dendrimers, NPs: Versatile Platforms for Sustained Brain Delivery
Polymeric Nanoparticles, Dendrimers, NPs: Versatile Platforms for Sustained Brain Delivery Open
Polymeric nanoparticles, dendrimers, and nanoparticles (NPs) represent a versatile platform for sustained brain delivery of therapeutic agents. These nanocarriers offer unique advantages in overcoming the blood-brain barrier (BBB) and achi…
View article: Advancements in nanotechnology for glaucoma detection and treatment: A focus on biosensors, IOP monitoring, and nano-drug delivery systems
Advancements in nanotechnology for glaucoma detection and treatment: A focus on biosensors, IOP monitoring, and nano-drug delivery systems Open
Biosensors are essential tools designed to monitor physiologically significant data for diverse applications, including environmental pollution detection, food safety, medication research, and disease diagnosis. The integration of microflu…
View article: Advances in neurotransmitter detection and modulation: Implications for neurological disorders
Advances in neurotransmitter detection and modulation: Implications for neurological disorders Open
Neurotransmitters are chemicals that amplify, transmit, and transform cellular impulses, facilitating communication across the neurological system. Over the last century, hundreds of these compounds have been identified, with continuous st…
View article: Demystifying the Role of Neuroinflammatory Mediators as Biomarkers for Diagnosis, Prognosis, and Treatment of Alzheimer’s Disease: A Review
Demystifying the Role of Neuroinflammatory Mediators as Biomarkers for Diagnosis, Prognosis, and Treatment of Alzheimer’s Disease: A Review Open
Neuroinflammatory mediators play a pivotal role in the pathogenesis of Alzheimer's Disease (AD), influencing its onset, progression, and severity. The precise mechanisms behind AD are still not fully understood, leading current treatments …
View article: Therapeutic landscape of natural products and emulgel in psoriasis
Therapeutic landscape of natural products and emulgel in psoriasis Open
Psoriasis, characterized by immune-mediated inflammation triggered by dysfunctions in the immune system, manifests in various skin areas with elevated plaques presenting as common symptoms. Traditional psoriasis treatments often incorporat…
View article: Herbal Emulgel Containing Azadirachta indica (Neem) and Nigella Sativa L. (Black Cumin) Oils in Wound Management: Preclinical Investigations
Herbal Emulgel Containing Azadirachta indica (Neem) and Nigella Sativa L. (Black Cumin) Oils in Wound Management: Preclinical Investigations Open
Context: In wound management, traditional use of plants has received attention by the scientific community, as traditional medicines are a valuable source of affordable, comprehensive medical care. Azadirachta indica A. Juss (Neem) and Nig…
View article: Revolutionizing Dosage Form Design: The Impact of 3D Printing in Pharmaceuticals
Revolutionizing Dosage Form Design: The Impact of 3D Printing in Pharmaceuticals Open
3D printing is revolutionizing pharmaceutical manufacturing by creating personalized dosage forms and intricate drug delivery systems. This technology offers flexibility and precision, enhancing patient compliance, reducing side effects, a…
View article: Transformative trends: A comprehensive review on role of artificial intelligence in healthcare and pharmaceutical research
Transformative trends: A comprehensive review on role of artificial intelligence in healthcare and pharmaceutical research Open
Artificial intelligence (AI) represents a specialized field within computer science, empowering machines to efficiently process and analyze intricate data. The surge in AI-focused research has notably accelerated, particularly in its growi…
View article: Moringa oleifera: A comprehensive review on pharmacology, phytochemistry, and clinical applications
Moringa oleifera: A comprehensive review on pharmacology, phytochemistry, and clinical applications Open
commonly referred to as the "tree of life" or the "miracle tree," holds wide spectrum of medicinal and non-medicinal benefits, and so it is valuable herbal plant. has been traditionally use for treating various disease conditions such as w…
View article: Through the eyes of Parkinson\'s: A narrative review of clinical spectrum and ophthalmological challenges in Parkinson’s disease
Through the eyes of Parkinson\'s: A narrative review of clinical spectrum and ophthalmological challenges in Parkinson’s disease Open
The ophthalmic non-motor dysfunctions are most common among individuals with Parkinson’s disease, manifesting both prior to motor symptoms and throughout the progression of the neurodegenerative condition. Detecting these impairments early…
View article: Oxidative stress and neurodegenerative diseases: Exploring natural antioxidants for therapeutic potential
Oxidative stress and neurodegenerative diseases: Exploring natural antioxidants for therapeutic potential Open
Neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, are a growing global health challenge with no definitive cure. Oxidative stress is implicated in these disorders, and antioxidants have emerged as a promisin…
View article: Recent advances in nanotherapeutics for epilepsy and neurodegenerative diseases
Recent advances in nanotherapeutics for epilepsy and neurodegenerative diseases Open
This review focuses on the potential of nanotherapeutics in the diagnosis and treatment of neuronal abnormal conditions particularly epilepsy, alzheimer's disease (AD), and Parkinson's disease (PD). The advancements in nanotechnology have …
View article: Navigating the cellular pathways: Chaperone-mediated autophagy as a targeted approach for management of parkinson\\\'s disease
Navigating the cellular pathways: Chaperone-mediated autophagy as a targeted approach for management of parkinson\\\'s disease Open
Parkinson's disease (PD) is a common neurodegenerative condition marked by the degeneration of dopaminergic neurons and the amassing of α-synuclein protein in Lewy bodies. Chaperone-mediated autophagy (CMA), a selective form of autophagy, …
View article: Novel therapeutic delivery for neurodegenerative diseases: Strategies to overcome CNS barriers
Novel therapeutic delivery for neurodegenerative diseases: Strategies to overcome CNS barriers Open
The incidence of central nervous system (CNS) diseases is expected to rise significantly due to increasing lifespan and changing population demographics. Among CNS diseases, neurodegenerative diseases (ND’s) entail a significant challenge …
View article: Endometrial cancer: Pathophysiology, diagnosis and management
Endometrial cancer: Pathophysiology, diagnosis and management Open
The most prevalent gynecologic disease is cancer of the endometrium, In the US, it is the fourth most prevalent malignancy in women after breast, lung, and colorectal malignancies. Despite a steady prevalence of sickness, during the past 2…
View article: Covid-19 Pandemic: A Curse to World
Covid-19 Pandemic: A Curse to World Open
The evolving coronavirus disease (COVID-19) spread across the world, affecting more than 200 countries and territories.The genomic analysis proposed that the COVID-19 virus first observed in bats and later spread to humans through unidenti…
View article: Foxo6 – A Novel Target for Parkinson’s Disease
Foxo6 – A Novel Target for Parkinson’s Disease Open
Introduction Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting more than 2% of people over the age of 50. There are more than 6 million cases of PD worldwide [1]. Over the past few years the prevalence…
View article: Herb drug interaction of Tinospora cordifolia (Willd.) Miers extract and Glimepiride: In vivo and in silico studies
Herb drug interaction of Tinospora cordifolia (Willd.) Miers extract and Glimepiride: In vivo and in silico studies Open
Tinospora cordifolia (Willd.) Miers (TC), family Menispermaceae is a well-known traditional herb reported in traditional Indian literature for the treatment of various disorders such as diabetes and cardiovascular diseases. Berberine, the …
View article: Natural products: An emerging tool in parkinson’s disease therapeutics
Natural products: An emerging tool in parkinson’s disease therapeutics Open
Natural products: An emerging tool in parkinson’s disease therapeutics - IJN- Print ISSN No: - 2581-8236 Online ISSN No:- 2581-916X Article DOI No:- 10.18231/j.ijn.2019.014, IP Indian Journal of Neurosciences-IP Indian J Neurosci