Partha Haldar
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View article: Impact of Medical and Surgical Treatment on Stigma among Persons with Epilepsy: A Systematic Review
Impact of Medical and Surgical Treatment on Stigma among Persons with Epilepsy: A Systematic Review Open
View article: Psychometric Evaluation of the Hindi Version of the Stigma Scale of Epilepsy: Results from an Exploratory Factor Analysis
Psychometric Evaluation of the Hindi Version of the Stigma Scale of Epilepsy: Results from an Exploratory Factor Analysis Open
View article: Patterns and predictors of cancer-associated ischemic stroke
Patterns and predictors of cancer-associated ischemic stroke Open
Objectives: Cancer-associated stroke (CAS) represents a unique ischemic stroke subtype with distinct mechanisms and poor prognosis. Our study aimed to evaluate CAS patient demographics, stroke patterns, and prognostic factors with a focus …
View article: Targeting a Tau Kinase Cdk5, Cyclin-Dependent Kinase: A Blood-Based Diagnostic Marker and Therapeutic Earmark for Alzheimer’s Disease
Targeting a Tau Kinase Cdk5, Cyclin-Dependent Kinase: A Blood-Based Diagnostic Marker and Therapeutic Earmark for Alzheimer’s Disease Open
Protein kinases are important molecules of Alzheimer’s Disease (AD), driving neuronal demise and the emergence of the disease’s destructive hallmarks. Cdk5 has recently been highlighted as a key therapeutic target for AD. This study evalua…
View article: Stigma, HIV Risk Behavior, and HIV Seropositivity among Hijra and Transgender in India: Insights from Integrated Biological and Behavioral Surveillance
Stigma, HIV Risk Behavior, and HIV Seropositivity among Hijra and Transgender in India: Insights from Integrated Biological and Behavioral Surveillance Open
Background: The hijra and transgender (H/TG) persons have enhanced risk of HIV infection. Objectives: We aimed to explore whether there were any associations between stigma, HIV risk behaviors, and HIV seropositivity among H/TG persons in …
View article: Efficacy of ketamine versus etomidate for rapid sequence intubation, among critically ill patients in terms of mortality and success rate: A systematic review and meta-analysis of randomized controlled trials
Efficacy of ketamine versus etomidate for rapid sequence intubation, among critically ill patients in terms of mortality and success rate: A systematic review and meta-analysis of randomized controlled trials Open
There is no difference in mortality outcomes for ketamine vs etomidate, when used for RSI in critically ill patients. ketamine, however, is associated with higher risk of post induction hypotension.
View article: Equitable Collaboration Between <scp>LMIC</scp> and <scp>HIC</scp> Researchers, Part I: A Preliminary Framework for Capacity Building in Psychiatric Genetics Research
Equitable Collaboration Between <span>LMIC</span> and <span>HIC</span> Researchers, Part I: A Preliminary Framework for Capacity Building in Psychiatric Genetics Research Open
International collaborations between high‐income countries (HICs) and low‐ and middle‐income countries (LMICs) have become increasingly essential in advancing global health, particularly within psychiatric research. These partnerships not …
View article: Anti-Inflammatory Peptide Prevents Aβ25–35-Induced Inflammation in Rats via Lipoxygenase Inhibition
Anti-Inflammatory Peptide Prevents Aβ25–35-Induced Inflammation in Rats via Lipoxygenase Inhibition Open
Neuroinflammation, triggered by lipoxygenase (LOX), contributes to Alzheimer’s disease (AD) progression. Overexpression of LOX-5 in patients with AD serum highlights its role. This study assessed the efficacy of the LOX-inhibitor-peptide Y…
View article: Assessment of Acute Stroke Care, Metrics and Outcomes: Analysis from the Pre-implementation Phase of the IMPETUS Study
Assessment of Acute Stroke Care, Metrics and Outcomes: Analysis from the Pre-implementation Phase of the IMPETUS Study Open
Background Stroke is a major cause of death and disability in India. Despite national programs and guidelines, stroke care continues to face challenges. Many stroke patients seek care at government medical colleges. To date, there are no s…
View article: Effect of prophylactic phenylephrine versus norepinephrine on foeto-maternal outcomes in caesarean delivery under neuraxial anaesthesia: A systematic review and meta-analysis with trial sequential analysis
Effect of prophylactic phenylephrine versus norepinephrine on foeto-maternal outcomes in caesarean delivery under neuraxial anaesthesia: A systematic review and meta-analysis with trial sequential analysis Open
Background and Aims: The prevention of hypotension in parturients scheduled for caesarean section is of utmost importance for improving foeto-maternal outcomes. We compared the prophylactic use of phenylephrine (PE) and norepinephrine (NE)…
View article: A randomised trial to assess the efficacy of add on therapy with aspirin or clopidogrel to the standard medical therapy alone in patients with tubercular meningitis: ACT TBM
A randomised trial to assess the efficacy of add on therapy with aspirin or clopidogrel to the standard medical therapy alone in patients with tubercular meningitis: ACT TBM Open
View article: Prevalence of Restless Legs Syndrome in Patients Who Underwent Percutaneous Coronary Intervention in a Tertiary Care Hospital: A Cross-Sectional Study
Prevalence of Restless Legs Syndrome in Patients Who Underwent Percutaneous Coronary Intervention in a Tertiary Care Hospital: A Cross-Sectional Study Open
Background and Objectives: Restless legs syndrome (RLS) is a risk for cardiovascular diseases and increases the risk of adverse cardiovascular outcomes following percutaneous coronary intervention (PCI). We aimed to determine the prevalenc…
View article: Optimal Systolic Blood Pressure Control After Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis
Optimal Systolic Blood Pressure Control After Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-analysis Open
Background and Objectives: The optimal systolic blood pressure (SBP) control after endovascular thrombectomy (EVT) is unclear. This study aimed to determine whether intensive SBP control (<140 mmHg) within 24 h post-EVT, compared to conven…
View article: Pregnancy and postpartum cardiometabolic outcomes among women with overt diabetes compared to women with normoglycaemia, gestational diabetes and pre‐existing diabetes: A systematic review and meta‐analysis
Pregnancy and postpartum cardiometabolic outcomes among women with overt diabetes compared to women with normoglycaemia, gestational diabetes and pre‐existing diabetes: A systematic review and meta‐analysis Open
Background and Aim Overt diabetes in pregnancy (ODiP) is a condition identified by the International Association of Diabetes and Pregnancy Study Groups (IADPSG) in 2010. Despite the clinical significance, our knowledge regarding its impact…
View article: Endovascular treatment for acute ischemic stroke due to medium vessel occlusion: A systematic review with meta-analysis and trial sequential analysis
Endovascular treatment for acute ischemic stroke due to medium vessel occlusion: A systematic review with meta-analysis and trial sequential analysis Open
Introduction A significant number of patients with acute ischemic stroke (AIS) due to medium vessel occlusion (MeVO) fail to achieve favourable functional outcomes despite the best medical treatment (BMT) currently available. The efficacy …
View article: Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors
Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors Open
Introduction: The optimal treatment of estrogen receptor-positive (ER +) metastatic breast cancer (MBC) after progression on cyclin-dependent 4/6 kinase inhibitors (CDK4/6i) is unknown. Methods: We conducted a systematic review and network…
View article: Serum Klotho: Unraveling its association with diagnosis and prognosis of breast cancer
Serum Klotho: Unraveling its association with diagnosis and prognosis of breast cancer Open
This study contributes a novel finding of serum Klotho protein in BC pathogenesis and explores its utility as a blood-based biomarker.
View article: Yoga as an Intervention for Tobacco Cessation - A Randomized Controlled Trial
Yoga as an Intervention for Tobacco Cessation - A Randomized Controlled Trial Open
View article: Effectiveness of Home-Based Self-monitoring of Blood Pressure in a Primary Care set-up of India (EASE-BP): Protocol for an Open-Label Randomized Controlled Trial
Effectiveness of Home-Based Self-monitoring of Blood Pressure in a Primary Care set-up of India (EASE-BP): Protocol for an Open-Label Randomized Controlled Trial Open
Background and Objectives: Rising hypertension from inadequate detection, noncompliance with treatment, and poor control presents a major public health challenge. Previously, adopting the strategy of self-monitoring of blood pressure (SMBP…
View article: Optimal Systolic Blood pressure control after thrombectomy in acute ischemic stroke-a systematic review and meta-analysis
Optimal Systolic Blood pressure control after thrombectomy in acute ischemic stroke-a systematic review and meta-analysis Open
Background and Objectives Although endovascular thrombectomy(EVT) is the standard of care for acute large vessel occlusions(LVO), optimal systolic blood pressure (SBP) control post procedure has remained elusive. Our study aimed to address…
View article: Human Immunodeficiency Virus Preexposure Prophylaxis Awareness and Acceptability among Men Who Have Sex with Men and Transgender Persons in India: Systematic Review and Meta-analysis
Human Immunodeficiency Virus Preexposure Prophylaxis Awareness and Acceptability among Men Who Have Sex with Men and Transgender Persons in India: Systematic Review and Meta-analysis Open
With increasing importance being given to preexposure prophylaxis (PrEP) for human immunodeficiency virus prevention among men who have sex with men (MSM) and transgender persons (TG), we undertook a systematic review and meta-analysis of …
View article: Long-Term Kinetics of SARS-CoV-2 Neutralizing and Anti-Receptor Binding Domain Antibodies among Laboratory-Confirmed COVID-19 Cases in Delhi National Capital Region, India: A Prospective, One-Year Follow-Up Study
Long-Term Kinetics of SARS-CoV-2 Neutralizing and Anti-Receptor Binding Domain Antibodies among Laboratory-Confirmed COVID-19 Cases in Delhi National Capital Region, India: A Prospective, One-Year Follow-Up Study Open
Background: This study was conducted with the objective of measuring the neutralizing and anti-receptor binding domain antibody levels against SARS-CoV-2 among laboratory-confirmed COVID-19 cases and exploring its long-term kinetics over a…
View article: Epidemiology of Geriatric Syndromes and Multimorbidity and Their Impact on Life Satisfaction: An Analysis of Longitudinal Ageing Study of India (LASI)
Epidemiology of Geriatric Syndromes and Multimorbidity and Their Impact on Life Satisfaction: An Analysis of Longitudinal Ageing Study of India (LASI) Open
View article: Anti-SARS-CoV-2 antibody kinetics up to 6 months of follow-up: Result from a nation-wide population-based, age stratified sero-epidemiological prospective cohort study in India
Anti-SARS-CoV-2 antibody kinetics up to 6 months of follow-up: Result from a nation-wide population-based, age stratified sero-epidemiological prospective cohort study in India Open
Repeated serological testing tells about the change in the overall infection in a community. This study aimed to evaluate changes in antibody prevalence and kinetics in a closed cohort over six months in different sub-populations in India.…
View article: Cell-Mediated Immunity (CMI) for SARS-CoV-2 Infection Among the General Population of North India: A Cross-Sectional Analysis From a Sub-sample of a Large Sero-Epidemiological Study
Cell-Mediated Immunity (CMI) for SARS-CoV-2 Infection Among the General Population of North India: A Cross-Sectional Analysis From a Sub-sample of a Large Sero-Epidemiological Study Open
Background Cell-mediated immunity (CMI), or specifically T-cell-mediated immunity, is proven to remain largely preserved against the variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including Omicron. The persisten…
View article: Description of HIV risk behavior among adolescent female sex workers: Findings from the nationwide cross-sectional integrated biological and behavioral surveillance (IBBS) 2014–15 survey for HIV in India
Description of HIV risk behavior among adolescent female sex workers: Findings from the nationwide cross-sectional integrated biological and behavioral surveillance (IBBS) 2014–15 survey for HIV in India Open
Introduction: Adolescent female sex workers are at high risk of acquiring human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection. There was paucity of information regarding their sexual practices. The main o…
View article: Utilization of HIV testing services among men who have sex with men inNew Delhi, India: A qualitative study on barriers and facilitators
Utilization of HIV testing services among men who have sex with men inNew Delhi, India: A qualitative study on barriers and facilitators Open
Background & objectives: In India, the prevalence of HIV among men who have sex with men (MSM), a core risk group for HIV was estimated to be 4.3%, 16 times higher than the national average. In Delhi, the estimated prevalence among MSM was…
View article: Effect of endovascular therapy in large anterior circulation ischaemic strokes: A systematic review and meta-analysis of randomised controlled trials
Effect of endovascular therapy in large anterior circulation ischaemic strokes: A systematic review and meta-analysis of randomised controlled trials Open
Introduction: The benefit of endovascular treatment in large anterior circulation ischaemic strokes with low ASPECTS score (<6) is uncertain. Recent randomised studies have demonstrated the benefit of endovascular treatment (EVT) in large …
View article: Risk factors associated with traumatic dental injuries in individuals with special healthcare needs—A systematic review and meta‐analysis
Risk factors associated with traumatic dental injuries in individuals with special healthcare needs—A systematic review and meta‐analysis Open
Background/Aim Individuals with special healthcare needs (SHCN) are more likely to sustain traumatic dental injuries (TDIs) due to distinct risk factors. The aim of this review was to assess various risk factors associated with TDIs in ind…
View article: Anti-SARS-CoV-2 Antibody Kinetics up to 6 months of follow-up: Result from a Nation-wide Population-based, Age Stratified Sero-Epidemiological Prospective Cohort Study in India
Anti-SARS-CoV-2 Antibody Kinetics up to 6 months of follow-up: Result from a Nation-wide Population-based, Age Stratified Sero-Epidemiological Prospective Cohort Study in India Open
Repeated serological testing tells about the change in the overall infection in a community. This study aimed to evaluate changes in antibody prevalence and kinetics in a closed cohort over six months in different sub-populations in India.…