Rola M. Labib
YOU?
Author Swipe
View article: Phytochemical Analysis and In Vivo Anticancer Effect of Becium grandiflorum: Isolation and Characterization of a Promising Cytotoxic Diterpene
Phytochemical Analysis and In Vivo Anticancer Effect of Becium grandiflorum: Isolation and Characterization of a Promising Cytotoxic Diterpene Open
Background:Becium grandiflorum is a fragrant perennial shrub of the Lamiaceae family. Objectives: The current study aimed to explore the cytotoxic potential of the n-hexane fraction from Becium grandiflorum aerial parts and, further, isola…
View article: A Comprehensive Review on Genus <i>Asystasia</i>: Folk Medicinal Uses, Phytoconstituents, and Pharmacological Activities
A Comprehensive Review on Genus <i>Asystasia</i>: Folk Medicinal Uses, Phytoconstituents, and Pharmacological Activities Open
Asystasia belongs to family Acanthaceae, which is a prominent family of dicotyledonous flowering plants encompassing various essential secondary metabolites that are crucial in numerous biological processes. Asystasia gangetica (L.) T. And…
View article: Gas Chromatography‐Mass Spectrometry Profiling of <i>Crateva magna</i> Leaf Lipophilic Extract and Evaluation of Its Anti‐Alzheimer and Cytotoxic Properties
Gas Chromatography‐Mass Spectrometry Profiling of <i>Crateva magna</i> Leaf Lipophilic Extract and Evaluation of Its Anti‐Alzheimer and Cytotoxic Properties Open
Alzheimer's disease (AD), one of the most common types of dementia, is an urgent and growing global challenge. AD pathogenesis is associated with increased activity of the acetylcholinesterase enzyme (AChE) and the β ‐site amyloid precurso…
View article: Family Malvaceae: a potential source of secondary metabolites with chemopreventive and anticancer activities supported with in silico pharmacokinetic and pharmacodynamic profiles
Family Malvaceae: a potential source of secondary metabolites with chemopreventive and anticancer activities supported with in silico pharmacokinetic and pharmacodynamic profiles Open
Introduction Cancer is the second most widespread cause of mortality following cardiovascular disorders, and it imposes a heavy global burden. Nowadays, herbal nutraceutical products with a plethora of bioactive metabolites represent a fou…
View article: Review of: "[Review Article] A Comprehensive Overview on Pharmacological and Therapeutic Insights of Solanum nigrum Linn"
Review of: "[Review Article] A Comprehensive Overview on Pharmacological and Therapeutic Insights of Solanum nigrum Linn" Open
Potential competing interests: No potential competing interests to declare.The review is very summative, but there are few mistakes in formatting.
View article: Review of: "Targeting Alzheimer's disease hallmarks with the Nrf2 activator Isoeugenol"
Review of: "Targeting Alzheimer's disease hallmarks with the Nrf2 activator Isoeugenol" Open
Potential competing interests: No potential competing interests to
View article: Insecticidal activity and phytochemical analysis of Pyrus communis L. extracts against malarial vector, Anopheles pharoensis Theobald, 1901 (Diptera: Culicidae)
Insecticidal activity and phytochemical analysis of Pyrus communis L. extracts against malarial vector, Anopheles pharoensis Theobald, 1901 (Diptera: Culicidae) Open
We aimed at investigating the insecticidal activity of Pyrus communis L. against the malarial vector, Anopheles pharoensis Theobald, 1901 and its phytochemical constituents. Leaves were collected and the crude extracts were prepared using …
View article: Metabolomic Profiles of Essential Oils from Selected Rosa Varieties and Their Antimicrobial Activities
Metabolomic Profiles of Essential Oils from Selected Rosa Varieties and Their Antimicrobial Activities Open
This study aimed to analyze the essential oils of the aerial parts (A) and flowers (F) of Rosa banksiae var. banksiae Ait. (RBW), Rosa polyantha Thunb. “orange fairy” (RPO) and Rosa polyantha Thunb. “white fairy” (RPW), family Rosaceae, an…
View article: The impact of seasonal variation on the volatile profile of leaves and stems of Brownea grandiceps (Jacq.) with evaluation of their anti-mycobacterial and anti-inflammatory activities
The impact of seasonal variation on the volatile profile of leaves and stems of Brownea grandiceps (Jacq.) with evaluation of their anti-mycobacterial and anti-inflammatory activities Open
Brownea species were used in folk medicine for the treatment of tuberculosis in South America. Volatile oils prepared by hydro-distillation from fresh leaves and stems of Brownea grandiceps Jacq. (Fabaceae) collected in different seasons w…
View article: A new stilbene from Agonis flexuosa leaves and verification of its histamine release inhibitory activity using in silico and in vitro studies
A new stilbene from Agonis flexuosa leaves and verification of its histamine release inhibitory activity using in silico and in vitro studies Open
This study aimed to explore the phytoconstituents of Agonis flexuosa, F. Myrtaceae and its biological activity. A thorough phytochemical investigation of its leaves led to the isolation of one new stilbene glycoside; (Z)-2,3-dihydroxystilb…
View article: Appraisal on the wound healing potential of Melaleuca alternifolia and Rosmarinus officinalis L. essential oil-loaded chitosan topical preparations
Appraisal on the wound healing potential of Melaleuca alternifolia and Rosmarinus officinalis L. essential oil-loaded chitosan topical preparations Open
The present study investigates the wound healing potential of three chitosan-based topical preparations loaded with either tea tree essential oil, rosemary essential oil or a mixture of both oils in vivo. Essential oils of M. alternifolia …
View article: Genus <i>Spondias</i>: A Phytochemical and Pharmacological Review
Genus <i>Spondias</i>: A Phytochemical and Pharmacological Review Open
It is believed that many degenerative diseases are due to oxidative stress. In view of the limited drugs available for treating degenerative diseases, natural products represent a promising therapeutic strategy in the search for new and ef…
View article: Chemical Composition of Pinus roxburghii Bark Volatile Oil and Validation of Its Anti-Inflammatory Activity Using Molecular Modelling and Bleomycin-Induced Inflammation in Albino Mice
Chemical Composition of Pinus roxburghii Bark Volatile Oil and Validation of Its Anti-Inflammatory Activity Using Molecular Modelling and Bleomycin-Induced Inflammation in Albino Mice Open
The chemical composition of Pinus roxburghii bark essential oil (PRO) was qualitatively and quantitatively determined using GC/FID and GC/MS. The anti-inflammatory activity was assessed in vitro by evaluating the binding percentages on the…
View article: Identification of phenolic secondary metabolites from <i>Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i>
Identification of phenolic secondary metabolites from <i>Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i> Open
Background Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied. The present work aimed at profiling the major phenolics compounds present in the hydro-alco…
View article: Identification of phenolic secondary metabolites from<i> Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i>
Identification of phenolic secondary metabolites from<i> Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i> Open
Background: Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied.The present work aimed at profiling the major phenolics compounds present in the hydro-alco…
View article: Identification of phenolic secondary metabolites from <i>Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i>
Identification of phenolic secondary metabolites from <i>Schotia brachypetala</i> Sond. (Fabaceae) and demonstration of their antioxidant activities in <i>Caenorhabditis elegans</i> Open
Background: Schotia brachypetala Sond. (Fabaceae) is an endemic tree of Southern Africa whose phytochemistry and pharmacology were slightly studied.The present work aimed at profiling the major phenolics compounds present in the hydro-alco…
View article: Ursolic Acid, a Natural Pentacylcic Triterpene from <i>Ochrosia elliptica</i> and Its Role in The Management of Certain Neglected Tropical Diseases.
Ursolic Acid, a Natural Pentacylcic Triterpene from <i>Ochrosia elliptica</i> and Its Role in The Management of Certain Neglected Tropical Diseases. Open
The fresh leaves of Ochrosia elleptica Labill., family Apocyanaceae are a reliable source of ursolic acid.Ursolic acid displayed considerable antitrypanosomal and antileishmanial activities. It showed superior antitrypanosomal activity as …