Roland Coppens
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View article: Switch to generic formulation of temozolomide results in statistically significant increase in grade 3 and 4 bone marrow toxicity in glioma patients in the province of Alberta
Switch to generic formulation of temozolomide results in statistically significant increase in grade 3 and 4 bone marrow toxicity in glioma patients in the province of Alberta Open
Background Temozolomide (TMZ) is an oral, systemic chemotherapy used chiefly for treating high-grade glioma. Due to the rising costs of systemic chemotherapy, many jurisdictions have replaced brand name with generic formulations. The aim o…
View article: Tamoxifen for Recurrent High-Grade Glioma: A Retrospective Study
Tamoxifen for Recurrent High-Grade Glioma: A Retrospective Study Open
The management of recurrence in patients with high-grade glioma remains controversial. The lack of clear molecular targets to guide systemic therapy for patients has resulted in the use of various systemic agents with modest efficacy but w…