Roland Diggelmann
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View article: Synchronization of visual perception within the human fovea
Synchronization of visual perception within the human fovea Open
The human brain constructs a model of the world by processing sensory signals with distinct temporal characteristics that may differ in generation and transmission speed within a single sensory modality. To perceive simultaneous events as …
View article: Multi-Functional HD-MEA Platform for High-Resolution Impedance Imaging and Electrophysiological Recordings of Brain Slices
Multi-Functional HD-MEA Platform for High-Resolution Impedance Imaging and Electrophysiological Recordings of Brain Slices Open
We present a high-resolution impedance imaging and electrophysiological recording platform and demonstrate its capabilities with brain slices. The platform is easy to operate featuring an efficient data acquisition system and user-friendly…
View article: Propagation speeds of action potentials in the human retina compensate for traveling distances
Propagation speeds of action potentials in the human retina compensate for traveling distances Open
Timing between action potentials is crucial for information processing in real neural networks. However, the physical axonal lengths largely determine the time necessary for action potentials to reach postsynaptic neurons. Retinal ganglion…
View article: Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map
Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map Open
Summary How closely human organoids recapitulate cell-type diversity and cell-type maturation of their target organs is not well understood. We developed human retinal organoids with multiple nuclear and synaptic layers. We sequenced the R…
View article: Automatic spike sorting for high-density microelectrode arrays
Automatic spike sorting for high-density microelectrode arrays Open
High-density microelectrode arrays can be used to record extracellular action potentials from hundreds to thousands of neurons simultaneously. Efficient spike sorters must be developed to cope with such large data volumes. Most existing sp…
View article: Effective benchmarking of high-density MEA spike-sorters
Effective benchmarking of high-density MEA spike-sorters Open
Event Abstract Back to Event Effective benchmarking of high-density MEA spike-sorters Roland Diggelmann1, 2*, Andreas R. Hierlemann1 and Felix Franke1 1 ETH Zürich, D-BSSE, Switzerland 2 Friedrich Miescher Institute for Biomedical Research…
View article: Large field-of-view HD-MEA setup for ex vivo mouse retina electrophysiological recordings
Large field-of-view HD-MEA setup for ex vivo mouse retina electrophysiological recordings Open
Event Abstract Back to Event Large field-of-view HD-MEA setup for ex vivo mouse retina electrophysiological recordings Matej Žnidarič1, 2*, Annalisa Bucci1, 2*, Roland Diggelmann1, 2, Andreas Hierlemann1 and Felix Franke1 1 ETH Zürich, Dep…
View article: UnitBrowser - A Tool to Evaluate and Post-Process Units Sorted by Automatic Spike Sorting Algorithms
UnitBrowser - A Tool to Evaluate and Post-Process Units Sorted by Automatic Spike Sorting Algorithms Open
Event Abstract Back to Event UnitBrowser - A Tool to Evaluate and Post-Process Units Sorted by Automatic Spike Sorting Algorithms Saad Idrees1*, Felix Franke2, Roland Diggelmann3, Andreas Hierlemann3 and Thomas Münch1 1 Eberhard Karls Univ…
View article: Using High-Density MEAs For High-Throughput Retinal Ganglion Cell Type Classification
Using High-Density MEAs For High-Throughput Retinal Ganglion Cell Type Classification Open
Event Abstract Back to Event Using High-Density MEAs For High-Throughput Retinal Ganglion Cell Type Classification Roland Diggelmann1*, Michele Fiscella1, Antonia Drinnenberg2, Felix Franke1, Botond Roska3 and Andreas Hierlemann4 1 ETH Zur…