Rolf Gedeborg
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View article: Optimised comorbidity indices can reflect patient performance status in register based studies of prostate cancer
Optimised comorbidity indices can reflect patient performance status in register based studies of prostate cancer Open
Eastern Cooperative Oncology Group Performance Status (ECOG-PS) is commonly used in cancer trials to select a study population with good performance, but ECOG-PS is rarely available in health-care registers. We assessed if patient age and …
View article: Discriminative Ability of the Charlson Comorbidity Index for Long-Term Mortality in a General Population: Nationwide, Population-Based Study of 10 Million Adults in Sweden
Discriminative Ability of the Charlson Comorbidity Index for Long-Term Mortality in a General Population: Nationwide, Population-Based Study of 10 Million Adults in Sweden Open
The CCI discriminated risk of death best using a look-back period of at least 5 years and performed better in women than in men in most age groups. Our findings offer insights into both the practical utility of the CCI and the interpretati…
View article: Urinary tract events after radical radiotherapy (RT) for prostate cancer according to pre‐RT International Prostate Symptom Score
Urinary tract events after radical radiotherapy (RT) for prostate cancer according to pre‐RT International Prostate Symptom Score Open
Objective To describe the risk of urinary tract events after radical radiotherapy (RT) according to pre‐RT (IPSS) overall and within subgroups of prostate volume, type of RT, and use of neoadjuvant androgen‐deprivation therapy (ADT), as me…
View article: Prostate cancer characteristics in fathers and risk of early onset high‐risk prostate cancer in sons
Prostate cancer characteristics in fathers and risk of early onset high‐risk prostate cancer in sons Open
A family history of prostate cancer in first‐degree relatives is an established risk factor for prostate cancer, but the specific associations between prostate cancer characteristics in fathers and the risk of high‐risk prostate cancer in …
View article: Figure S1 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Figure S1 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
The figure describes consequences of calendar time on the selection of study population for the sensitivity analyses.
View article: Figure S3 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Figure S3 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
A Kaplan-Meier plot describing the time to prostate cancer death, comparing men with and without a family history of prostate cancer.
View article: Table S1 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S1 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
The table describes the operational definition of prostate cancer risk categories used in the study, in relation to the National Comprehensive Cancer Network (NCCN) definitions.
View article: Table S3 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S3 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results of sensitivity analyses restricted to men whose fathers were born after 1920
View article: Data from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Data from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Background:A family history (FH) of prostate cancer increases the risk of prostate cancer, but its association with prostate cancer mortality remains unclear.Methods:FH was defined as having a first-degree relative who was diagnosed before…
View article: Table S10 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S10 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results from sensitivity analysis restricted to men diagnosed before 75 years of age.
View article: Table S5 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S5 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results of sensitivity analysis where exposure was handled as a time-varying covariate, i.e., handle the situation if father or a brother was diagnosed with PCa after the man in the study was diagnosed with PCa.
View article: Figure S2 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Figure S2 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
The figure is a flow chart describing the extraction of the study population(s).
View article: Table S9 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S9 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results from sensitivity analysis restricted to men diagnosed before 66 years of age.
View article: Table S6 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S6 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Sensitivity analysis for associations a family history using two mutually exclusive exposure groups: (i) A stronger exposure definition requiring family history to early onset or lethal prostate cancera, and (ii) a weaker exposure definiti…
View article: Table S2 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S2 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
The table describes details of family history in the study population, comparing men with and without early onset (age
View article: Table S8 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S8 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results from sensitivity analyses for the association between family history and characteristics at diagnosis, restricted to men whose fathers were born after 1920.
View article: Table S4 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S4 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results of sensitivity analysis where follow-up was censored if exposure status changed, i.e., the father or a brother being diagnosed with PCa after the man in the study was diagnosed with PCa.
View article: Figure S4 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Figure S4 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
A Directed Acyclic Graph (DAG) describing a hypothesized causal structure between family history of prostate cancer and prostate cancer death
View article: Table S7 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Table S7 from Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Results of sensitivity analysis restricted to men diagnosed before January 1, 2010.
View article: Potential gains from radical treatment of men with prostate cancer according to life expectancy
Potential gains from radical treatment of men with prostate cancer according to life expectancy Open
Objectives To investigate the impact of age and life expectancy on treatment decisions and its consequences for outcomes among men with intermediate and high‐risk prostate cancer (PCa). Materials and methods We studied men in Prostate Canc…
View article: Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden
Family History of Early Onset or Lethal Prostate Cancer and the Risk of Prostate Cancer Death in Sweden Open
Background: A family history (FH) of prostate cancer increases the risk of prostate cancer, but its association with prostate cancer mortality remains unclear. Methods: FH was defined as having a first-degree relative who was diagnosed bef…
View article: A comparison of comorbidity indices and estimates of life expectancy for men with prostate cancer
A comparison of comorbidity indices and estimates of life expectancy for men with prostate cancer Open
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View article: Prostate cancer incidence in Sweden before, during and after the COVID-19 pandemic. Population-based study
Prostate cancer incidence in Sweden before, during and after the COVID-19 pandemic. Population-based study Open
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View article: Radical Treatment for Prostate Cancer in Men With Limited Life Expectancy in Sweden
Radical Treatment for Prostate Cancer in Men With Limited Life Expectancy in Sweden Open
This cohort study compares rates of radical treatment for prostate cancer, despite current guideline recommendations that discourage its use for men with limited life expectancy, in Sweden and the US.
View article: Non‐steroidal anti‐inflammatory drugs and risk of kidney cancer: A Swedish nationwide cohort study in the general and high‐use populations
Non‐steroidal anti‐inflammatory drugs and risk of kidney cancer: A Swedish nationwide cohort study in the general and high‐use populations Open
Background Data on the association between non‐steroidal anti‐inflammatory drugs (NSAIDs) and kidney cancer (KC) are conflicting. This study aimed to evaluate this association in the general population and in patients with extensive NSAID …
View article: Improved adherence to prostate cancer guidelines concomitant with public reporting. Nationwide population-based study
Improved adherence to prostate cancer guidelines concomitant with public reporting. Nationwide population-based study Open
Background: Swedish national guidelines provide evidence-based recommendations for standard of care; however, little is known about adherence to them. The aim of this study was to assess adherence to management guidelines for prostate canc…
View article: Functional outcomes after primary vs delayed robot-assisted radical prostatectomy following active surveillance
Functional outcomes after primary vs delayed robot-assisted radical prostatectomy following active surveillance Open
Background It is unknown if a period of active surveillance before prostatectomy for prostate cancer (PCa) worsens functional outcomes. The aim of this study was to compare functional outcomes after primary vs delayed robot-assisted radica…
View article: Incidence and prognostic implications of prostate-specific antigen persistence and relapse after radical prostatectomy: population-based study
Incidence and prognostic implications of prostate-specific antigen persistence and relapse after radical prostatectomy: population-based study Open
Background There has been a wide range in incidence of prostate-specific antigen (PSA) persistence and relapse after radical prostatectomy (RP) for prostate cancer (PCa). We aimed to describe incidence and prognostic implications of PSA pe…
View article: Assessment of variability in life expectancy in older men by use of new comorbidity indices. A nationwide population-based study
Assessment of variability in life expectancy in older men by use of new comorbidity indices. A nationwide population-based study Open
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