Roman Lyttleton
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View article: Practically Error-Free Junctions Enable Solving Large Instances of Exact Cover Problems Using Network-Based Biocomputation
Practically Error-Free Junctions Enable Solving Large Instances of Exact Cover Problems Using Network-Based Biocomputation Open
Network-based biocomputing (NBC) presents an energy-efficient, parallel computing approach for solving nondeterministic polynomial time (NP) complete problems by leveraging motor-driven cytoskeletal filaments that explore all possible solu…
View article: Motility of an autonomous protein-based artificial motor that operates via a burnt-bridge principle
Motility of an autonomous protein-based artificial motor that operates via a burnt-bridge principle Open
Inspired by biology, great progress has been made in creating artificial molecular motors. However, the dream of harnessing proteins – the building blocks selected by nature – to design autonomous motors has so far remained elusive. Here w…
View article: Exploitation of Engineered Light-Switchable Myosin XI for Nanotechnological Applications
Exploitation of Engineered Light-Switchable Myosin XI for Nanotechnological Applications Open
For certain nanotechnological applications of the contractile proteins actin and myosin, e.g., in biosensing and network-based biocomputation, it would be desirable to temporarily switch on/off motile function in parts of nanostructured de…
View article: The Effect of Direct Electron Beam Patterning on the Water Uptake and Ionic Conductivity of Nafion Thin Films
The Effect of Direct Electron Beam Patterning on the Water Uptake and Ionic Conductivity of Nafion Thin Films Open
The effect of electron‐beam patterning on the water uptake and ionic conductivity of Nafion films using a combination of X‐ray photoelectron spectroscopy, quartz crystal microbalance studies, neutron reflectometry, and impedance spectrosco…
View article: Solving the 3‐Satisfiability Problem Using Network‐Based Biocomputation
Solving the 3‐Satisfiability Problem Using Network‐Based Biocomputation Open
The 3‐satisfiability Problem (3‐SAT) is a demanding combinatorial problem that is of central importance among the nondeterministic polynomial (NP) complete problems, with applications in circuit design, artificial intelligence, and logisti…
View article: Roadmap for network-based biocomputation
Roadmap for network-based biocomputation Open
Network-based biocomputation (NBC) is an alternative, parallel computation approach that can potentially solve technologically important, combinatorial problems with much lower energy consumption than electronic processors. In NBC, a combi…
View article: Solving the 3-SAT problem using network-based biocomputation
Solving the 3-SAT problem using network-based biocomputation Open
The 3-Satisfiability Problem (3-SAT) is a demanding combinatorial problem, of central importance among the non-deterministic polynomial (NP) complete problems, with applications in circuit design, artificial intelligence and logistics. Eve…
View article: Through the Eyes of Creators: Observing Artificial Molecular Motors
Through the Eyes of Creators: Observing Artificial Molecular Motors Open
Inspired by molecular motors in biology, there has been significant progress in building artificial molecular motors, using a number of quite distinct approaches. As the constructs become more sophisticated, there is also an increasing nee…
View article: Prolonged function and optimization of actomyosin motility for upscaled network-based biocomputation
Prolonged function and optimization of actomyosin motility for upscaled network-based biocomputation Open
Significant advancements have been made towards exploitation of naturally available molecular motors and their associated cytoskeletal filaments in nanotechnological applications. For instance, myosin motors and actin filaments from muscle…
View article: Prospects for single-molecule electrostatic detection in molecular motor gliding motility assays
Prospects for single-molecule electrostatic detection in molecular motor gliding motility assays Open
Molecular motor gliding motility assays based on myosin/actin or kinesin/microtubules are of interest for nanotechnology applications ranging from cargo-trafficking in lab-on-a-chip devices to novel biocomputation strategies. Prototype sys…
View article: Prospects for single-molecule electrostatic detection in molecular motor gliding motility assays
Prospects for single-molecule electrostatic detection in molecular motor gliding motility assays Open
Molecular motor gliding motility assays based on myosin/actin or kinesin/microtubules are of interest for nanotechnology applications ranging from cargo-trafficking in lab-on-a-chip devices to novel biocomputation strategies. Prototype sys…
View article: Integrated bioelectronic proton-gated logic elements utilizing nanoscale patterned Nafion
Integrated bioelectronic proton-gated logic elements utilizing nanoscale patterned Nafion Open
We report fully monolithic, nanoscale logic elements featuring n- and p-type nanowires as electronic channels that are proton-gated by electron-beam patterned Nafion giving DC gain exceeding 5 and frequency response up to 2 kHz.
View article: Achieving short high-quality gate-all-around structures for horizontal nanowire field-effect transistors
Achieving short high-quality gate-all-around structures for horizontal nanowire field-effect transistors Open
We introduce a fabrication method for gate-all-around nanowire field-effect transistors. Single nanowires were aligned perpendicular to underlying bottom gates using a resist-trench alignment technique. Top gates were then defined aligned …
View article: Using Ultrathin Parylene Films as an Organic Gate Insulator in Nanowire Field-Effect Transistors
Using Ultrathin Parylene Films as an Organic Gate Insulator in Nanowire Field-Effect Transistors Open
We report the development of nanowire field-effect transistors featuring an ultrathin parylene film as a polymer gate insulator. The room temperature, gas-phase deposition of parylene is an attractive alternative to oxide insulators prepar…