Roman Teimer
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A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex Open
Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs), which are formed from multiple copies of ~30 different nucleoporins (Nups) and inserted into the double nuclear membrane. Many of these Nups are organized into subco…
View article: Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Molecular architecture of the inner ring scaffold of the human nuclear pore complex Open
Blueprint for a macromolecular machine Nuclear pore complexes (NPCs) consist of around 1000 protein subunits, are embedded in the membrane that surrounds the nucleus, and regulate transport between the nucleus and the cytoplasm. Although t…