Ron J. Karni
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View article: Additional evidence from a case report supports a novel hypothesis on the association between complex regional pain syndrome and lymphedema
Additional evidence from a case report supports a novel hypothesis on the association between complex regional pain syndrome and lymphedema Open
A previous report of 4 heterogeneous cases demonstrated that automated manual lymphatic drainage therapy (AMLDT), administered by a novel, pneumatic mat of 16 pressurized air channels that inflate and deflate sequentially to mimic the stre…
View article: Using content validity index methodology for cross-cultural translation of a patient-reported outcome measure for head and neck cancer
Using content validity index methodology for cross-cultural translation of a patient-reported outcome measure for head and neck cancer Open
Introduction Translations of patient-reported measures may not account for structural and cultural differences in shared languages spoken in multiple countries, such as English, Spanish, Arabic, or Russian. The objective of this research w…
View article: Case Report: The effect of automated manual lymphatic drainage therapy on lymphatic contractility in 4 distinct cases
Case Report: The effect of automated manual lymphatic drainage therapy on lymphatic contractility in 4 distinct cases Open
Introduction Automated manual lymphatic drainage therapy (AMLDT) is available for home use in the form of a pneumatic mat of 16 pressurized air channels that inflate and deflate to mimic the stretch and release action of manual lymphatic d…
View article: Synchronous Presentation of Right Parotid Branchial Cleft Cyst and Left Neck HPV-Associated Cystic Metastatic Squamous Cell Carcinoma: A Diagnostic Quandary
Synchronous Presentation of Right Parotid Branchial Cleft Cyst and Left Neck HPV-Associated Cystic Metastatic Squamous Cell Carcinoma: A Diagnostic Quandary Open
Branchial cleft cyst arising within the parotid space is considered an extremely rare phenomenon. In contrast, cystic squamous cell carcinoma in the lateral neck is not an uncommon presentation of HPV-related head and neck cancer. Although…
View article: Infected Ruptured Parathyroid Cyst Presenting with Hypercalcemia and Airway Obstruction: A Case Report
Infected Ruptured Parathyroid Cyst Presenting with Hypercalcemia and Airway Obstruction: A Case Report Open
Parathyroid cysts (PC) are infrequently encountered and characterize less than 1% of all head and neck masses. When present, PCs may present as a palpable neck mass and lead to hypercalcemia and rarely respiratory depression. Furthermore, …
View article: NUT Carcinoma of the Submandibular Gland: A Case at This Uncommon Site with Review of the Literature
NUT Carcinoma of the Submandibular Gland: A Case at This Uncommon Site with Review of the Literature Open
View article: Aerosol Production with Surgical Instrumentation: Implications for Head and Neck Surgery in the COVID-19 Era
Aerosol Production with Surgical Instrumentation: Implications for Head and Neck Surgery in the COVID-19 Era Open
View article: Oligometastatic Parathyroid Carcinoma Presenting as Neck Pain: A Case Report
Oligometastatic Parathyroid Carcinoma Presenting as Neck Pain: A Case Report Open
Background: Parathyroid carcinoma (PC) is an exceedingly rare, slow-growing but progressive endocrine malignancy that represents a diagnostic and therapeutic challenge. Vertebral metastasis of PC is remarkable, with only 3 prior cases of s…
View article: Lymphatic Dissemination and Axillary Web Syndrome in Primary Cutaneous Tuberculosis Secondary to Needlestick Injury
Lymphatic Dissemination and Axillary Web Syndrome in Primary Cutaneous Tuberculosis Secondary to Needlestick Injury Open
Cutaneous tuberculosis secondary to skin inoculation of Mycobacterium tuberculosis is uncommon but it can occur in the health care settings. Herein, we report an unusual case of primary cutaneous tuberculosis of the thumb following a needl…
View article: HSV Pseudotumor of the Hypopharynx: A Diagnostic Challenge
HSV Pseudotumor of the Hypopharynx: A Diagnostic Challenge Open
A 50-year-old male presented with HIV and an ulcerative mass on the hypopharynx. Initially thought to be malignant, multiple biopsies and surgeries over 19 months did not resolve the lesion. Discovery of the cytopathic effect on biopsy led…
View article: Longitudinal effects of a novel advanced pneumatic compression device on patient‐reported outcomes in the management of cancer‐related head and neck lymphedema: A preliminary report
Longitudinal effects of a novel advanced pneumatic compression device on patient‐reported outcomes in the management of cancer‐related head and neck lymphedema: A preliminary report Open
Background Head and neck cancer (HNC) survivors experience head and neck lymphedema (HNL), which requires treatment to prevent morbidity. We explore the self‐reported outcomes and satisfaction of patients with HNC receiving treatment for H…
View article: Assessing lymphatic route of CSF outflow and peripheral lymphatic contractile activity during head‐down tilt using near‐infrared fluorescence imaging
Assessing lymphatic route of CSF outflow and peripheral lymphatic contractile activity during head‐down tilt using near‐infrared fluorescence imaging Open
Evidence overwhelmingly suggests that the lymphatics play a critical role in the clearance of cerebrospinal fluid (CSF) from the cranial space. Impairment of CSF outflow into the lymphatics is associated with a number of pathological condi…
View article: Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework
Povidone-iodine solution as SARS-CoV-2 prophylaxis for procedures of the upper aerodigestive tract a theoretical framework Open
Background The COVID-19 pandemic has raised concerns of inadvertent SARS-CoV-2 transmission to healthcare workers during routine procedures of the aerodigestive tract in asymptomatic COVID-19 patients. Current efforts to mitigate this risk…
View article: Head and Neck Lymphedema: Treatment Response to Single and Multiple Sessions of Advanced Pneumatic Compression Therapy
Head and Neck Lymphedema: Treatment Response to Single and Multiple Sessions of Advanced Pneumatic Compression Therapy Open
Ten head and neck cancer survivors diagnosed with head and neck lymphedema (HNL) were imaged using near‐infrared fluorescence lymphatic imaging (NIRFLI) prior to and immediately after an initial advance pneumatic compression device treatme…
View article: Metastatic parathyroid carcinoma presenting as an osteolytic cervical vertebral mass 5 years after parathyroidectomy
Metastatic parathyroid carcinoma presenting as an osteolytic cervical vertebral mass 5 years after parathyroidectomy Open
Introduction: Parathyroid carcinoma is a rare malignancy that is challenging to diagnose, with metastasis regarded as the only true way to differentiate parathyroid carcinoma from adenoma. Case presentation: A 63 year-old woman presented t…
View article: Morphoproteomics, E6/E7 in-situ hybridization, and biomedical analytics define the etiopathogenesis of HPV-associated oropharyngeal carcinoma and provide targeted therapeutic options
Morphoproteomics, E6/E7 in-situ hybridization, and biomedical analytics define the etiopathogenesis of HPV-associated oropharyngeal carcinoma and provide targeted therapeutic options Open
Background Human papillomavirus (HPV) has been identified as an etiopathogenetic factor in oropharyngeal squamous cell carcinoma. The HPV E6 and E7 oncogenes are instrumental in promoting proliferation and blocking differentiation leading …
View article: Interpretation of Tc-99m sestamibi parathyroid SPECT-CT scans made easy for better surgical outcomes in patients with primary hyperparathyroidism
Interpretation of Tc-99m sestamibi parathyroid SPECT-CT scans made easy for better surgical outcomes in patients with primary hyperparathyroidism Open
Objective: This study aims to evaluate the accuracy of Tc-99m sestamibi parathyroid scan (SPS) with single-photon emission computerized tomography/computerized tomography (SPECT/CT) in patients with primary hyperparathyroidism after optimi…
View article: Comparing success rates of anesthesia providers versus trauma surgeons in their use of palpation to identify the cricothyroid membrane in female subjects: a prospective observational study
Comparing success rates of anesthesia providers versus trauma surgeons in their use of palpation to identify the cricothyroid membrane in female subjects: a prospective observational study Open
View article: Dermal Backflow Seen Through Near-Infrared Fluorescence Imaging: An Early Response to Cancer Treatments in Head and Neck for the Detection of Lymphedema
Dermal Backflow Seen Through Near-Infrared Fluorescence Imaging: An Early Response to Cancer Treatments in Head and Neck for the Detection of Lymphedema Open
View article: Morphoproteomics Identifies the EZH2 Pathways as a Potential Therapeutic Target of Human Papillomavirus–Associated Oropharyngeal Cancer
Morphoproteomics Identifies the EZH2 Pathways as a Potential Therapeutic Target of Human Papillomavirus–Associated Oropharyngeal Cancer Open
View article: Medrobotics Flex System for Laryngeal Surgery: A Feasible Study in Two Cadavers
Medrobotics Flex System for Laryngeal Surgery: A Feasible Study in Two Cadavers Open
Objective To report the feasibility of Medrobotics Flex® System for laryngeal surgery. Materials and methods Cadaver study in research laboratory. Results The Medrobotics Flex System was utilized with the Medrobotics Flex Retractor to eval…