Ronald A. Karwoski
YOU?
Author Swipe
View article: Voxel-Wise Comparison of Co-Registered Quantitative CT and Hyperpolarised Gas Diffusion-Weighted MRI Measurements in IPF
Voxel-Wise Comparison of Co-Registered Quantitative CT and Hyperpolarised Gas Diffusion-Weighted MRI Measurements in IPF Open
The patterns of idiopathic pulmonary fibrosis (IPF) lung disease that directly correspond to elevated hyperpolarised gas diffusion-weighted (DW) MRI metrics are currently unknown. This study aims to develop a spatial co-registration framew…
View article: Pulmonary vessel volume in idiopathic pulmonary fibrosis compared with healthy controls aged > 50 years
Pulmonary vessel volume in idiopathic pulmonary fibrosis compared with healthy controls aged > 50 years Open
Idiopathic pulmonary fibrosis (IPF) is characterised by progressive fibrosing interstitial pneumonia with an associated irreversible decline in lung function and quality of life. IPF prevalence increases with age, appearing most frequently…
View article: Evaluation of automated airway morphological quantification for assessing fibrosing lung disease
Evaluation of automated airway morphological quantification for assessing fibrosing lung disease Open
Abnormal airway dilatation, termed traction bronchiectasis, is a typical feature of idiopathic pulmonary fibrosis (IPF). Volumetric computed tomography (CT) imaging captures the loss of normal airway tapering in IPF. We postulated that aut…
View article: Differentiation of Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Related Interstitial Lung Disease Using Quantitative Imaging
Differentiation of Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Related Interstitial Lung Disease Using Quantitative Imaging Open
A usual interstitial pneumonia (UIP) imaging pattern can be seen in both idiopathic pulmonary fibrosis (IPF) and connective tissue disease-related interstitial lung disease (CTD-ILD). The purpose of this multicenter study was to assess whe…
View article: Correction to: Vessel-related structures predict UIP pathology in those with a non-IPF pattern on CT
Correction to: Vessel-related structures predict UIP pathology in those with a non-IPF pattern on CT Open
View article: Generic User-guided Interaction Paradigm for Precise Post-slice-wise Processing of Tomographic Deep Learning Segmentations Utilizing Graph Cut and Graph Segmentation
Generic User-guided Interaction Paradigm for Precise Post-slice-wise Processing of Tomographic Deep Learning Segmentations Utilizing Graph Cut and Graph Segmentation Open
View article: Validation of the BRODERS classifier (Benign<i>versus</i>aggRessive nODule Evaluation using Radiomic Stratification), a novel HRCT-based radiomic classifier for indeterminate pulmonary nodules
Validation of the BRODERS classifier (Benign<i>versus</i>aggRessive nODule Evaluation using Radiomic Stratification), a novel HRCT-based radiomic classifier for indeterminate pulmonary nodules Open
Introduction Implementation of low-dose chest computed tomography (CT) lung cancer screening and the ever-increasing use of cross-sectional imaging are resulting in the identification of many screen- and incidentally detected indeterminate…
View article: Automated CT Analysis of Major Forms of Interstitial Lung Disease
Automated CT Analysis of Major Forms of Interstitial Lung Disease Open
This study aimed to determine diagnostic and prognostic differences in major forms of interstitial lung disease using quantitative CT imaging. A retrospective study of 225 subjects with a multidisciplinary diagnosis of idiopathic pulmonary…
View article: Do we need to see to believe?—radiomics for lung nodule classification and lung cancer risk stratification
Do we need to see to believe?—radiomics for lung nodule classification and lung cancer risk stratification Open
Despite multiple recent advances, the diagnosis and management of lung cancer remain challenging and it continues to be the deadliest malignancy. In 2011, the National Lung Screening Trial (NLST) reported 20% reduction in lung cancer relat…
View article: Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis
Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis Open
Change in the vessel-related structures, a computer-derived CT variable, is a strong predictor of outcome in idiopathic pulmonary fibrosis and can increase power in future drug trials when used as a co-endpoint alongside forced vital ca…
View article: Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD
Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD Open
Presence and severity of emphysema in patients with COPD, as quantified by CT metrics and radiomics can be estimated by mathematical modeling of airway function as derived from standard spirometry.
View article: Computed Tomography–Based Score Indicative of Lung Cancer Aggression (SILA) Predicts the Degree of Histologic Tissue Invasion and Patient Survival in Lung Adenocarcinoma Spectrum
Computed Tomography–Based Score Indicative of Lung Cancer Aggression (SILA) Predicts the Degree of Histologic Tissue Invasion and Patient Survival in Lung Adenocarcinoma Spectrum Open
View article: Sa1659 – Comparison of Changes in Rectal Area and Volume During Mr Evacuation Proctography in Healthy and Constipated Adults
Sa1659 – Comparison of Changes in Rectal Area and Volume During Mr Evacuation Proctography in Healthy and Constipated Adults Open
View article: Comparison of changes in rectal area and volume during MR evacuation proctography in healthy and constipated adults
Comparison of changes in rectal area and volume during MR evacuation proctography in healthy and constipated adults Open
Background During proctography, rectal emptying is visually estimated by the reduction in rectal area. The correlation between changes in rectal area, which is a surrogate measure of volume, is unclear. Our aims were to compare the change …
View article: Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis
Longitudinal prediction of outcome in idiopathic pulmonary fibrosis using automated CT analysis Open
AIMS To evaluate computer-derived (CALIPER) CT variables against FVC change as potential drug trials endpoints in IPF. METHODS 71 Royal Brompton Hospital (discovery cohort) and 23 Mayo Clinic Rochester and 24 St Antonius Hospital Nieuwegei…
View article: Predicting outcomes in rheumatoid arthritis related interstitial lung disease
Predicting outcomes in rheumatoid arthritis related interstitial lung disease Open
The aim of this study was to compare radiology-based prediction models in rheumatoid arthritis-related interstitial lung disease (RAILD) to identify patients with a progressive fibrosis phenotype. RAILD patients had computed tomography (CT…
View article: Correction: Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial
Correction: Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial Open
[This corrects the article DOI: 10.1371/journal.pone.0196910.].
View article: Assessment of Interstitial Lung Disease Using Lung Ultrasound Surface Wave Elastography
Assessment of Interstitial Lung Disease Using Lung Ultrasound Surface Wave Elastography Open
Purpose: Optimal strategies to detect early interstitial lung disease (ILD) are unknown. ILD is frequently subpleural in distribution and affects lung elasticity. Lung ultrasound surface wave elastography (LUSWE) is a noninvasive method of…
Assessing the inter-observer variability of Computer-Aided Nodule Assessment and Risk Yield (CANARY) to characterize lung adenocarcinomas Open
View article: Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions
Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions Open
The majority of incidentally and screen-detected lung cancers are adenocarcinomas. Optimal management of these tumors is clinically challenging due to variability in tumor histopathology and behavior. Invasive adenocarcinoma (IA) is genera…
View article: Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial
Novel high-resolution computed tomography-based radiomic classifier for screen-identified pulmonary nodules in the National Lung Screening Trial Open
[This corrects the article DOI: 10.1371/journal.pone.0196910.].
View article: Predicting Outcomes in Idiopathic Pulmonary Fibrosis Using Automated Computed Tomographic Analysis
Predicting Outcomes in Idiopathic Pulmonary Fibrosis Using Automated Computed Tomographic Analysis Open
Our study has validated a new quantitative CT measure in patients with IPF fulfilling drug trial entry criteria-the VRS score-that outperformed current gold standard measures of outcome. When used for cohort enrichment in an IPF drug trial…
View article: CANARY Segmentation of Lung Adenocarcinoma v1
CANARY Segmentation of Lung Adenocarcinoma v1 Open
Computer-Aided Nodule Assessment and Risk Yield (CANARY) is a novel computed tomography (CT) tool developed at Mayo Clinic (Rochester, MN) that characterizes earlylung adenocarcinoma by detecting nine distinct voxel classes, representing a…
View article: Likelihood of pulmonary hypertension in patients with idiopathic pulmonary fibrosis and emphysema
Likelihood of pulmonary hypertension in patients with idiopathic pulmonary fibrosis and emphysema Open
Background and objective This study evaluated whether patients with combined pulmonary fibrosis and emphysema (CPFE) have an increased likelihood of pulmonary hypertension (PHT) when compared with idiopathic pulmonary fibrosis (IPF) patien…
View article: Unclassifiable-interstitial lung disease: Outcome prediction using CT and functional indices
Unclassifiable-interstitial lung disease: Outcome prediction using CT and functional indices Open
View article: Functional and prognostic effects when emphysema complicates idiopathic pulmonary fibrosis
Functional and prognostic effects when emphysema complicates idiopathic pulmonary fibrosis Open
This study aimed to investigate whether the combination of fibrosis and emphysema has a greater effect than the sum of its parts on functional indices and outcome in idiopathic pulmonary fibrosis (IPF), using visual and computer-based (CAL…
View article: Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis
Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis Open
Pulmonary vessel volume can identify CHP patients at risk of aggressive disease and a poor IPF-like prognosis.
View article: Evaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study
Evaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study Open
CALIPER-derived pulmonary vessel volume is an independent predictor of mortality across all CTD-ILD patients. Furthermore, automated stratification of CALIPER CT variables represents a novel method of prognostication at least as robust as …
View article: Mortality prediction in idiopathic pulmonary fibrosis: evaluation of computer-based CT analysis with conventional severity measures
Mortality prediction in idiopathic pulmonary fibrosis: evaluation of computer-based CT analysis with conventional severity measures Open
Computer-based computed tomography (CT) analysis can provide objective quantitation of disease in idiopathic pulmonary fibrosis (IPF). A computer algorithm, CALIPER, was compared with conventional CT and pulmonary function measures of dise…
View article: Appreciating the shades of gray: a case for Computer-Aided Nodule Assessment and Risk Yield (CANARY)-based risk stratification of lung adenocarcinomas
Appreciating the shades of gray: a case for Computer-Aided Nodule Assessment and Risk Yield (CANARY)-based risk stratification of lung adenocarcinomas Open
We read with great interest the invited commentary by Drs. Wilson and Pu on our computed tomography (CT)-based quantitative imaging tool for the non-invasive risk stratification of lung adenocarcinomas: Computer-Aided Nodule Assessment and…