Rong‐Bin Liang
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View article: Correction: Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights
Correction: Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights Open
View article: Assessing the quality of myopia prevention videos on Chinese short video platforms: a cross-sectional content analysis by source
Assessing the quality of myopia prevention videos on Chinese short video platforms: a cross-sectional content analysis by source Open
Objectives The prevalence of myopia has been rising, whereas prevention efforts have shown limited success. Educational short videos have become crucial sources for health information; however, their quality regarding myopia prevention is …
View article: Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights
Adipose-derived stem cells extracellular vesicles enhance diabetic wound healing via CCN2/PI3K/AKT pathway: therapeutic potential and mechanistic insights Open
Background Adipose-derived stem cells extracellular vesicles (ADSCs-EVs) hold significant promise in tissue repair and regeneration. While they have been reported to enhance diabetic wound healing, the precise mechanisms remain unclear. Me…
View article: Structural changes in the retina and choroid in patients with different degrees of myopia
Structural changes in the retina and choroid in patients with different degrees of myopia Open
View article: Cancer antigen 153: A risk factor for ocular metastases in patients with breast cancer
Cancer antigen 153: A risk factor for ocular metastases in patients with breast cancer Open
Ocular metastasis (OM) in breast cancer (BC) always predicts poor prognosis. The present study explored differences in tumor markers in patients with BC with and without OM, and attempted to determine risk factors for OM in patients with B…
View article: VEGFA may be a potential marker of myopic choroidal thickness and vascular density changes
VEGFA may be a potential marker of myopic choroidal thickness and vascular density changes Open
View article: Causal relationships between inflammatory cytokines and myopia: an analysis of genetic and observational studies
Causal relationships between inflammatory cytokines and myopia: an analysis of genetic and observational studies Open
Objective: This study aims to explore the causal relationship between inflammatory markers and myopia through the use of bidirectional Mendelian randomization (MR) and myopia animal models. Methods: The authors utilized data from a compreh…
View article: Proteomic insights into myopia development: Differential protein expression and the role of calcium signaling in form deprivation myopia in Guinea pigs
Proteomic insights into myopia development: Differential protein expression and the role of calcium signaling in form deprivation myopia in Guinea pigs Open
This study aims to explore the changes in the vitreous proteomics of form deprivation myopia (FDM) in guinea pigs, in order to reveal the molecular mechanisms involved in the onset and development of myopia. The myopia model in guinea pigs…
View article: Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia
Effect of exogenous calcitriol on myopia development and axial length in guinea pigs with form deprivation myopia Open
The annual increase in myopia prevalence poses a significant economic and health challenge. Our study investigated the effect of calcitriol role in myopia by inducing the condition in guinea pigs through form deprivation for four weeks. Un…
View article: Targeting scleral remodeling and myopia development in form deprivation myopia through inhibition of EFEMP1 expression
Targeting scleral remodeling and myopia development in form deprivation myopia through inhibition of EFEMP1 expression Open
The role of extracellular matrix (ECM) remodeling in the axial elongation associated with myopia has not been fully elucidated, although it is considered a significant factor. EFEMP1, a regulator of ECM, has been associated with various pa…
View article: Altered brain network centrality in patients with orbital fracture: A resting‑state functional MRI study
Altered brain network centrality in patients with orbital fracture: A resting‑state functional MRI study Open
The present study aimed to investigate potential functional network brain-activity abnormalities in individuals with orbital fracture (OF) using the voxel-wise degree centrality (DC) technique. The present study included 20 patients with O…
View article: Ocular microvascular alteration in Sjögren’s syndrome treated with hydroxychloroquine: an OCTA clinical study
Ocular microvascular alteration in Sjögren’s syndrome treated with hydroxychloroquine: an OCTA clinical study Open
Background: Sjögren’s syndrome (SjS) is a rare autoimmune disease, and despite our knowledge of SjS, we still lack effective treatments. Chloroquine drugs used to treat autoimmune diseases are still the primary medicine for SjS but increas…
View article: VEGFA may be a potential marker of myopic choroidal thickness and vascular density changes
VEGFA may be a potential marker of myopic choroidal thickness and vascular density changes Open
Introduction: To evaluate the changes of choroidal thickness（CT） and blood flow related to myopia, and its effects of vascular endothelial growth factor (VEGFA) on choroidal vessels in myopia. Methods: 137 subjects were included and divide…
View article: The Predictive Value of CA-125 and Hb for Ocular Metastasis in Hepatocellular Carcinoma Patients
The Predictive Value of CA-125 and Hb for Ocular Metastasis in Hepatocellular Carcinoma Patients Open
Our data suggest that CA-125 and Hb are risk indicators in hepatocellular carcinoma patients with OM, and that CA-125+Hb has potentially greater utility in diagnosing hepatocellular carcinoma.
View article: Altered regional homogeneity of spontaneous brain activity in patients with toothache: A resting-state functional magnetic resonance imaging study
Altered regional homogeneity of spontaneous brain activity in patients with toothache: A resting-state functional magnetic resonance imaging study Open
Toothache (TA) is a common and severe pain, but its effects on the brain are somewhat unclear. In this study, functional magnetic resonance imaging (fMRI) was used to compare regional homogeneity (ReHo) between TA patients and a normal con…
View article: Microvascular alterations in the diagnosis of systemic sclerosis: a new approach
Microvascular alterations in the diagnosis of systemic sclerosis: a new approach Open
The study investigated the conjunctival and fundus retinal vascular density changes in individuals with systemic sclerosis (SSc) by optical coherence tomography angiography (OCTA) to clarify the relationship between these changes and clini…
View article: Retinal microvasculature alteration in patients with systemic sclerosis and chloroquine treatment
Retinal microvasculature alteration in patients with systemic sclerosis and chloroquine treatment Open
The OCTA results suggest that retinal MIR density is decreased in SSc patients, and that long-term use of chloroquine will aggravate this damage, resulting in a further decrease in retinal MIR density.
View article: Detection of Abnormal Spontaneous Brain Activity Patterns in Patients With Orbital Fractures Using Fractional Amplitude of Low Frequency Fluctuation
Detection of Abnormal Spontaneous Brain Activity Patterns in Patients With Orbital Fractures Using Fractional Amplitude of Low Frequency Fluctuation Open
Background To date, no in-depth study has been conducted on the intrinsic pathological relationship between altered brain activity and related behavioral changes in patients with orbital fracture (OF). Purpose The present research aimed to…
View article: Corrigendum: Characteristics of the Fractional Amplitude of Low-Frequency Fluctuation in Ocular Hypertension Patients: A Resting-State fMRI Study
Corrigendum: Characteristics of the Fractional Amplitude of Low-Frequency Fluctuation in Ocular Hypertension Patients: A Resting-State fMRI Study Open
[This corrects the article DOI: 10.3389/fmed.2021.687420.].
View article: Abnormal Fractional Amplitude of Low Frequency Fluctuation Changes in Patients With Dry Eye Disease: A Functional Magnetic Resonance Imaging Study
Abnormal Fractional Amplitude of Low Frequency Fluctuation Changes in Patients With Dry Eye Disease: A Functional Magnetic Resonance Imaging Study Open
Purpose To investigate spontaneous brain activity in patients with dry eye (DE) and healthy control (HC) using the fractional amplitude of low frequency fluctuation (fALFF) technique with the aim of elucidating the relationship between the…
View article: Correction for: Altered regional brain white matter in dry eye patients: a brain imaging study
Correction for: Altered regional brain white matter in dry eye patients: a brain imaging study Open
View article: Neuron-Specific Enolase and Hemoglobin as Risk Factors of Intraocular Metastasis in Patients with Renal Cell Carcinoma
Neuron-Specific Enolase and Hemoglobin as Risk Factors of Intraocular Metastasis in Patients with Renal Cell Carcinoma Open
Renal cell carcinoma (RCC) appears to be a high risk of spread. This research investigated the correlation between a different range of clinical features and intraocular metastasis (IOM) in RCC patients and attempted to determine potential…
View article: Characteristics of the Fractional Amplitude of Low-Frequency Fluctuation in Ocular Hypertension Patients: A Resting-State fMRI Study
Characteristics of the Fractional Amplitude of Low-Frequency Fluctuation in Ocular Hypertension Patients: A Resting-State fMRI Study Open
Background The fractional amplitude of low-frequency fluctuation (fALFF) method has been underutilized in research on the pathogenesis and clinical manifestations of ocular hypertension (OH). Purpose This study uses resting state functiona…
View article: Altered Spontaneous Brain Activity Patterns in Children With Strabismic Amblyopia After Low-Frequency Repetitive Transcranial Magnetic Stimulation: A Resting-State Functional Magnetic Resonance Imaging Study
Altered Spontaneous Brain Activity Patterns in Children With Strabismic Amblyopia After Low-Frequency Repetitive Transcranial Magnetic Stimulation: A Resting-State Functional Magnetic Resonance Imaging Study Open
Objective Previous studies have demonstrated altered brain activity in strabismic amblyopia (SA). In this study, low-frequency repetitive transcranial magnetic stimulation (rTMS) was applied in children with strabismic amblyopia after they…
View article: Altered Brain Activity in Patients With Comitant Strabismus Detected by Analysis of the Fractional Amplitude of Low-Frequency Fluctuation: A Resting-State Functional MRI Study
Altered Brain Activity in Patients With Comitant Strabismus Detected by Analysis of the Fractional Amplitude of Low-Frequency Fluctuation: A Resting-State Functional MRI Study Open
More and more studies showed that strabismus is not simply an ocular disease, but a neuro-ophthalmology disease. To analyze potential changes in brain activity and their relationship to behavioral performance in comitant strabismus patient…
View article: Altered regional brain white matter in dry eye patients: a brain imaging study
Altered regional brain white matter in dry eye patients: a brain imaging study Open
This study aimed to investigate the regional changes of brain white matter (WM) in DE patients using diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). A total of 25 dry eye patients (PAT) and 25…
View article: Abnormal fractional amplitude of low-frequency fluctuations in MOG-lgG optic neuritis patients: a resting-state functional MRI study
Abnormal fractional amplitude of low-frequency fluctuations in MOG-lgG optic neuritis patients: a resting-state functional MRI study Open
Optic neuritis (ON) is a general term for inflammation of any part of the optic nerve resulting from demyelination or infection. The number of patients with MOG-lgG antibody-related optic neuritis is increasing recently. Our study uses the…
View article: Functional Connectivity Hypointensity of Middle Cingulate Gyrus and Thalamus in Age-Related Macular Degeneration Patients: A Resting-State Functional Magnetic Resonance Imaging Study
Functional Connectivity Hypointensity of Middle Cingulate Gyrus and Thalamus in Age-Related Macular Degeneration Patients: A Resting-State Functional Magnetic Resonance Imaging Study Open
Objective Age-related macular degeneration (AMD) causes visual damage and blindness globally. The purpose of this study was to investigate changes in functional connectivity (FC) in AMD patients using resting-state functional magnetic reso…
View article: The Correlation Between Atmospheric Conditions and Clinical Dry Eye
The Correlation Between Atmospheric Conditions and Clinical Dry Eye Open
Objective: To explore the correlation between dry eye and levels of the atmospheric pollutants ozone (O 3 ) and nitric dioxide (NO 2 ), and its application in the prediction, prevention and personalized medical treatment of dry eye. Method…
View article: Abnormal Intrinsic Functional Hubs in Corneal Ulcer: Evidence from a Voxel-Wise Degree Centrality Analysis
Abnormal Intrinsic Functional Hubs in Corneal Ulcer: Evidence from a Voxel-Wise Degree Centrality Analysis Open
Background: Numerous anterior neuroimaging researches have revealed that corneal ulcers (CU) are related to changes in cerebral anatomic structure and functional area. Nonetheless, functional characteristics of the brain’s network organiza…