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View article: Cannabinoid receptor 2 affect the inflammatory response in periodontitis by regulating macrophage M1/M2 polarization
Cannabinoid receptor 2 affect the inflammatory response in periodontitis by regulating macrophage M1/M2 polarization Open
CB2R deficiency exacerbates alveolar bone resorption and inflammatory severity in periodontitis, potentially by dysregulating macrophage M1/M2 polarization and inflammatory cytokine expression.
View article: Source analysis of nitrate pollution in a typical tributary of the upper Yellow River using a combined approach of stable isotopes and DOM fluorescence characteristics
Source analysis of nitrate pollution in a typical tributary of the upper Yellow River using a combined approach of stable isotopes and DOM fluorescence characteristics Open
Identifying the sources and characteristics of water pollution is essential for the protection and management of water environments. Nitrate (NO 3 − ) is a key pollutant affecting water quality in the Qingshui River, a typical semi‐arid tr…
View article: The Magnetometer for the Solar Wind Magnetosphere Ionosphere Link Explorer
The Magnetometer for the Solar Wind Magnetosphere Ionosphere Link Explorer Open
View article: A simulation study of the impact of population-wide lifestyle modifications on life expectancy in the Chinese population
A simulation study of the impact of population-wide lifestyle modifications on life expectancy in the Chinese population Open
View article: Integrative Proteome- and Phenome-Wide Assessment Uncovers Causal Protein Drivers and Drug Targets for Heterogeneous Kidney Diseases
Integrative Proteome- and Phenome-Wide Assessment Uncovers Causal Protein Drivers and Drug Targets for Heterogeneous Kidney Diseases Open
Interpreting proteomic associations with chronic kidney disease (CKD) is challenging due to the disease’s clinical heterogeneity and complex overlap with systemic conditions. We present a framework that identifies causal circulating protei…
View article: Agent Bain vs. Agent McKinsey: A New Text-to-SQL Benchmark for the Business Domain
Agent Bain vs. Agent McKinsey: A New Text-to-SQL Benchmark for the Business Domain Open
In the business domain, where data-driven decision making is crucial, text-to-SQL is fundamental for easy natural language access to structured data. While recent LLMs have achieved strong performance in code generation, existing text-to-S…
View article: Dietary oregano essential oil supplementation improves intestinal barrier function and modulates the cecal microbiota and metabolites of beef cattle
Dietary oregano essential oil supplementation improves intestinal barrier function and modulates the cecal microbiota and metabolites of beef cattle Open
Background The health of the hindgut in beef cattle plays a crucial role in their growth and overall health. Oregano essential oil (OEO) has gained attention as a potential alternative to antibiotics due to its various beneficial propertie…
View article: Coupled non-Hermitian skin effect with exceptional points
Coupled non-Hermitian skin effect with exceptional points Open
View article: lncRNA RNA AC114812 Regulates the Inflammatory Response of Periodontal Ligament Cells via the miR-181a-5p-SPP1 Axis
lncRNA RNA AC114812 Regulates the Inflammatory Response of Periodontal Ligament Cells via the miR-181a-5p-SPP1 Axis Open
By regulating the expression of long non-coding RNA AC114812, the inflammatory response can be alleviated, thereby affecting cell proliferation and migration. The effect may be achieved through the miR-181a-5p-SPP1 axis. These can provide …
View article: Respiratory pathogens in infants and young children with acute respiratory illness: a prospective cohort study, China, 2023–2024
Respiratory pathogens in infants and young children with acute respiratory illness: a prospective cohort study, China, 2023–2024 Open
Background Infants are vulnerable to acute respiratory infections (ARIs), which result in pediatric morbidity and even fatalities. A surge of ARIs among infants and young children was reported in China in 2023, garnering global attention. …
View article: Characterization of the Nicotinamide Adenine Dinucleotide Biosynthesis Pathway and Regulatory Mechanisms in <scp> <i>Streptococcus mutans</i> </scp>
Characterization of the Nicotinamide Adenine Dinucleotide Biosynthesis Pathway and Regulatory Mechanisms in <span> <i>Streptococcus mutans</i> </span> Open
NAD + and its derivatives, which act as redox coenzymes, are crucial for cellular metabolism and energy production. Nevertheless, the processes by which Streptococcus mutans , a bacterium known for causing dental caries, synthesizes NAD + …
View article: Integrating multi‐ancestry genomic and proteomic data to identify blood risk biomarkers and target proteins for breast cancer genetic risk loci
Integrating multi‐ancestry genomic and proteomic data to identify blood risk biomarkers and target proteins for breast cancer genetic risk loci Open
Genome‐wide association studies (GWAS) have identified more than 200 risk loci for breast cancer. However, target genes and their encoded proteins in these loci remain largely unknown. In this study, we utilized genetic prediction models f…
View article: Size-dependent aggregation of erythrocytes by low molecular weight hyaluronic acids of different sizes: bioactivity and quality control potential
Size-dependent aggregation of erythrocytes by low molecular weight hyaluronic acids of different sizes: bioactivity and quality control potential Open
Introduction Hyaluronic acid (HA) is a crucial biological molecule whose diverse functions are strongly influenced by its molecular weight. In particular, low molecular weight HA (LMW-HA) fragments—such as HA60 (average 60 kDa), HA35 (aver…
View article: High-accuracy vertical wind profiling up to 12 km using a 1064 nm coherent Doppler Lidar with 10 mJ pulsed laser
High-accuracy vertical wind profiling up to 12 km using a 1064 nm coherent Doppler Lidar with 10 mJ pulsed laser Open
We present a high-performance coherent Doppler wind Lidar (CDWL) system designed for long-range vertical and horizontal wind field detection. The system utilizes a self-developed single-frequency pulsed Nd:YAG laser operating at 1064 nm, d…
View article: Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants
Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants Open
Kidney dysfunction is a major cause of mortality, but its genetic architecture remains elusive. In this study, we conducted a multiancestry genome-wide association study in 2.2 million individuals and identified 1026 (97 previously unknown…
View article: Implementation and Comparative Analysis of Surface Acoustic Wave Sensor Readout Circuit Architectures: Delay-Line Versus Resonator Configurations
Implementation and Comparative Analysis of Surface Acoustic Wave Sensor Readout Circuit Architectures: Delay-Line Versus Resonator Configurations Open
View article: A Study on the Impact of Professional Identity on Learning Engagement of Chinese English Normal Students
A Study on the Impact of Professional Identity on Learning Engagement of Chinese English Normal Students Open
View article: Recovery and environmental driving mechanisms of attached algae communities during the near-natural restoration of urban rivers
Recovery and environmental driving mechanisms of attached algae communities during the near-natural restoration of urban rivers Open
View article: Investigating the Influence of Heterogeneous Fracture Permeability on Egs Performance Using Supercritical Co2 as Working Fluid
Investigating the Influence of Heterogeneous Fracture Permeability on Egs Performance Using Supercritical Co2 as Working Fluid Open
View article: An Extended Euler-Bernoulli Beam Principle in Bi-Component Metamaterial Towards Programmable Poisson's Ratio
An Extended Euler-Bernoulli Beam Principle in Bi-Component Metamaterial Towards Programmable Poisson's Ratio Open
View article: Synergistic Effect of Ag Nanoparticles and Oxygen Vacancies: Towards Efficient Co2 Reduction of Biobr in Gas-Solid Phase
Synergistic Effect of Ag Nanoparticles and Oxygen Vacancies: Towards Efficient Co2 Reduction of Biobr in Gas-Solid Phase Open
View article: Trapping nanoscale particles <i>via</i> quasi-Scholte mode in acoustofluidics
Trapping nanoscale particles <i>via</i> quasi-Scholte mode in acoustofluidics Open
A thin-foil-based quasi-Scholte wave acoustofluidic device is developed for stable nanoscale particle trapping, offering a low-frequency, simple and scalable platform for bioengineering and nanofabrication.
View article: A Rapid Field-Visualization Detection Platform for Genetically Modified Soybean ‘Zhonghuang 6106’ Based on RPA-CRISPR
A Rapid Field-Visualization Detection Platform for Genetically Modified Soybean ‘Zhonghuang 6106’ Based on RPA-CRISPR Open
Genetically modified (GM) herbicide-tolerant soybean ‘Zhonghuang 6106’, which introduces a glyphosate-resistant gene, ensures soybean yield while allowing farmers to reduce the use of other herbicides, thereby reducing weed management cost…
View article: Real-Time and Ultrasensitive Prostate-Specific Antigen Sensing Using Love-Mode Surface Acoustic Wave Immunosensor Based on MoS2@Cu2O-Au Nanocomposites
Real-Time and Ultrasensitive Prostate-Specific Antigen Sensing Using Love-Mode Surface Acoustic Wave Immunosensor Based on MoS2@Cu2O-Au Nanocomposites Open
Prostate-specific antigen (PSA) is a well-established tumour marker for prostatic carcinoma. In this study, we present a novel, real-time, and ultrasensitive Love-mode surface acoustic wave (L-SAW) immunosensor for PSA detection enhanced b…
View article: Atherosclerotic renal artery stenosis, mediating biomarkers, and risk of cardiac among individuals with hypertension: A real-world study
Atherosclerotic renal artery stenosis, mediating biomarkers, and risk of cardiac among individuals with hypertension: A real-world study Open
View article: High-Performance Ammonia QCM Sensor Based on SnO2 Quantum Dots/Ti3C2Tx MXene Composites at Room Temperature
High-Performance Ammonia QCM Sensor Based on SnO2 Quantum Dots/Ti3C2Tx MXene Composites at Room Temperature Open
Ammonia (NH3) gas is prevalent in industrial production as a health hazardous gas. Consequently, it is essential to develop a straightforward, reliable, and stable NH3 sensor capable of operating at room temperature. This paper presents an…
View article: Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction
Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction Open
View article: <i>GLP1R</i> Gene Expression and Kidney Disease Progression
<i>GLP1R</i> Gene Expression and Kidney Disease Progression Open
Importance Glucagon-like peptide 1 receptor agonists (GLP-1RAs) may have nephroprotective properties beyond those related to weight loss and glycemic control. Objective To investigate the association of genetically proxied GLP-1RAs with ki…
View article: Experimental study on recycling rubber to increase the impact resistance of cement mortar
Experimental study on recycling rubber to increase the impact resistance of cement mortar Open
View article: Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes
Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes Open