Rongjun Wang
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View article: Detection and genetic diversity of Cryptosporidium in yaks in Xinjiang, China
Detection and genetic diversity of Cryptosporidium in yaks in Xinjiang, China Open
Cryptosporidium spp. is an important protozoan parasite that can cause diarrhea in both humans and animals worldwide. In the present study, a total of 826 yak fecal samples were collected from six counties in Xinjiang and tested for Crypto…
View article: MiR-125b-5p targets Bak1 to regulate HCT-8 cell apoptosis in response to Cryptosporidium parvum infection via mitochondrial pathway
MiR-125b-5p targets Bak1 to regulate HCT-8 cell apoptosis in response to Cryptosporidium parvum infection via mitochondrial pathway Open
Background Cryptosporidium parvum infection can regulate apoptosis of host epithelial cells through both extrinsic and intrinsic apoptotic pathways, potentially involving various microRNAs (miRNAs). This study focuses on the role of miR-12…
View article: Study on Chemical Channeling Control Technology of Hydrocarbon Gas Flooding in Mahu Tight Conglomerate Reservoir
Study on Chemical Channeling Control Technology of Hydrocarbon Gas Flooding in Mahu Tight Conglomerate Reservoir Open
In view of the problem that the enhanced oil recovery of hydrocarbon gas drive is limited by gas channeling between injection and production wells after volume fracturing of horizontal wells in tight reservoirs, this paper combines the geo…
View article: Epidemiological Shifts in Children Respiratory Pathogens in Shenzhen, China: A Comparative Analysis Before and After the Relaxation of COVID‐19 Non‐Pharmaceutical Interventions
Epidemiological Shifts in Children Respiratory Pathogens in Shenzhen, China: A Comparative Analysis Before and After the Relaxation of COVID‐19 Non‐Pharmaceutical Interventions Open
Background The COVID‐19 pandemic and associated non‐pharmaceutical interventions significantly altered the epidemiology of respiratory pathogens. This study aimed to evaluate the changes in the prevalence and distribution of respiratory pa…
View article: Sympatric non-biting flies serve as potential vectors of zoonotic protozoan parasites on pig farms in China
Sympatric non-biting flies serve as potential vectors of zoonotic protozoan parasites on pig farms in China Open
Background Cryptosporidium spp., Enterocytozoon bieneusi , and Blastocystis sp. are common enteric parasites in humans and pigs. Ascertaining whether non-biting flies (NBFs) serve as potential vectors of these parasites on pig farms is a c…
View article: Licochalcone a: A promising antiparasitic drug against giardiasis
Licochalcone a: A promising antiparasitic drug against giardiasis Open
Giardiasis, caused by Giardia duodenalis, is a prevalent and significant zoonotic disease. While nitroimidazole drugs are primarily used to treat giardiasis, the urgent need for the development and formulation of new drugs has arisen due t…
View article: The Development Potential and Challenges of One-Click Generative Artificial Intelligence in Cross-Border E-Commerce
The Development Potential and Challenges of One-Click Generative Artificial Intelligence in Cross-Border E-Commerce Open
This paper explores the development potential and challenges of one-click generative artificial intelligence (AI) in cross-border e-commerce. With the rapid growth of the Internet, cross-border e-commerce has seen significant market expans…
View article: MiR-199a-3p regulates HCT-8 cell autophagy and apoptosis in response to Cryptosporidium parvum infection by targeting MTOR
MiR-199a-3p regulates HCT-8 cell autophagy and apoptosis in response to Cryptosporidium parvum infection by targeting MTOR Open
The microRNAs (miRNAs) of their hosts play an important role in regulating both the innate and adaptive immune responses to Cryptosporidium parvum infection. The mechanisms of autophagy and apoptosis are important components of the defense…
View article: miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway
miR-181d targets BCL2 to regulate HCT-8 cell apoptosis and parasite burden in response to Cryptosporidium parvum infection via the intrinsic apoptosis pathway Open
Cryptosporidium parvum is an important zoonotic pathogen that is studied worldwide. MicroRNAs (miRNAs) act as post-transcriptional regulators and may play a key role in modulating host epithelial responses following Cryptosporidium infecti…
View article: MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection
MiR-3976 regulates HCT-8 cell apoptosis and parasite burden by targeting BCL2A1 in response to Cryptosporidium parvum infection Open
Background Cryptosporidium is second only to rotavirus as a cause of moderate-to-severe diarrhea in young children. There are currently no fully effective drug treatments or vaccines for cryptosporidiosis. MicroRNAs (miRNAs) are involved i…
View article: A marked decline of Taenia solium taeniasis and cysticercosis infections in China: possible reasons from ecological determinant perspectives
A marked decline of Taenia solium taeniasis and cysticercosis infections in China: possible reasons from ecological determinant perspectives Open
Taenia solium taeniasis/cysticercosis is an important global food-borne infectious diseases transmitted between humans and pigs. According to both national surveys and field prevalence investigations, the prevalence of the disease in China…
View article: A Marked Decline in Taenia solium Taeniasis and Cysticercosis Infections in China: Possible Reasons from the Ecological Determinants Perspective
A Marked Decline in Taenia solium Taeniasis and Cysticercosis Infections in China: Possible Reasons from the Ecological Determinants Perspective Open
Taenia solium taeniasis/cysticercosis is an important global food-borne infectious disease transmitted between humans and pigs. According to both national surveys and field investigations, the prevalence of the disease in China has signifi…
View article: Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Background Cryptosporidium species are zoonotic protozoans that are important causes of diarrhoeal disease in both humans and animals. Non-coding RNAs (ncRNAs) play an important role in the innate immune defense against Cryptosporidium inf…
View article: MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection
MiR-942-5p targeting the IFI27 gene regulates HCT-8 cell apoptosis via a TRAIL-dependent pathway during the early phase of Cryptosporidium parvum infection Open
Background MicroRNAs (miRNAs) are involved in the regulation of both the innate and adaptive immune response to Cryptosporidium parvum infection. We previously reported that C. parvum upregulated miR‑942‑5p expression in HCT‑8 cells via TL…
View article: Molecular detection and phylogeny of Anaplasma spp. closely related to Anaplasma phagocytophilum in small ruminants from China
Molecular detection and phylogeny of Anaplasma spp. closely related to Anaplasma phagocytophilum in small ruminants from China Open
The genus Anaplasma comprises eight bacterial species that are obligate intracellular pathogens that affect human and animal health. The zoonotic species A. phagocytophilum is the causative agent of tick-borne fever in ruminants, and of gr…
View article: Development of a qPCR to diagnose the genus Eimeria in sheep and goats
Development of a qPCR to diagnose the genus Eimeria in sheep and goats Open
Coccidiosis of sheep and goats is caused by protozoa in the genus Eimeria . These protozoa mainly affect young animals, causing a decrease in production and consequent economic losses. Routine diagnosis is made through morphological observ…
View article: Additional file 4 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 4 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 4: Table S4. The GO and KEGG enrichment analysis of cis‑ and trans- target genes for dif-lncRNAs at 3 hpi and 12 hpi.
View article: Additional file 5 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 5 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 5: Table S5. The GO and KEGG enrichment analysis of dif-mRNAs at 3 hpi and 12 hpi.
View article: Additional file 7 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 7 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 7: Table S7. The GO and KEGG enrichment analysis of sponging miRNA targets for the dif-circRNA at 12 hpi.
View article: Additional file 6 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 6 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 6: Table S6. The GO and KEGG enrichment analysis of target genes for dif-miRNAs at 3 hpi and 12 hpi.
View article: Additional file 2 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 2 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 2: Table S2. The differentially expressed mRNAs, lncRNAs, miRNAs and circRNA at 3 hpi and 12 hpi.
View article: Additional file 3 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum
Additional file 3 of Whole transcriptome analysis of HCT-8 cells infected by Cryptosporidium parvum Open
Additional file 3: Table S3. The cis- and trans- target genes predicted for dif-lncRNAs at 3 hpi and 12 hpi.
View article: Subtyping of Blastocystis infection in common quails (Coturnix coturnix) in Xinxiang city of China
Subtyping of Blastocystis infection in common quails (Coturnix coturnix) in Xinxiang city of China Open
Blastocystis is a unicellular anaerobic intestinal protist primarily of various animal species worldwide, and has been reported to inhabit humans as well. Blastocystis infections and subtype identification have been documented in China, al…
View article: Comparison of 11 respiratory pathogens among hospitalized children before and during the COVID-19 epidemic in Shenzhen, China
Comparison of 11 respiratory pathogens among hospitalized children before and during the COVID-19 epidemic in Shenzhen, China Open
Background The effect of SARS-CoV-2 on existing respiratory pathogens in circulation remains uncertain. This study aimed to assess the impact of SARS-CoV-2 on the prevalence of respiratory pathogens among hospitalized children. Methods Thi…